Brief Information of the Compound and Protein
Compound Name
3-[[7-[5-chloro-3-methyl-2-(piperidin-3-ylamino)phenyl]thieno[3,2-b]pyridin-2-yl]methyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2,4-dione
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PubChem ID
CID: 156013528
Canonical SMILES
Cc1cc(Cl)cc(c1NC1CCCNC1)-c1ccnc2cc(CN3C(=O)C4C(C3=O)C4(C)C)sc12
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Compound Formula C27H29ClN4O2S
Compound Structure
Protein Name
Ubiquitin carboxyl-terminal hydrolase 7
Protein Classification
Enzyme
>
Protease
>
Cysteine protease
>
Cysteine protease CA clan
>
Cysteine protease C19 family
Uniprot ID
Q93009
Gene Name
USP7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000189 RKO Homo sapiens (Human)  1
1
EC50 = 33 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.78 nM