Brief Information of the Compound and Protein
Compound Name
1-[[7-[5-chloro-2-[(3R,4S)-4-fluoropyrrolidin-3-yl]oxy-3-methylphenyl]thieno[3,2-b]pyridin-2-yl]methyl]pyrrolidine-2,5-dione
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PubChem ID
CID: 138610287
Canonical SMILES
Cc1cc(Cl)cc(c1O[C@@H]1CNC[C@@H]1F)-c1ccnc2cc(CN3C(=O)CCC3=O)sc12
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Compound Formula C23H21ClFN3O3S
Compound Structure
Protein Name
Ubiquitin carboxyl-terminal hydrolase 7
Protein Classification
Enzyme
>
Protease
>
Cysteine protease
>
Cysteine protease CA clan
>
Cysteine protease C19 family
Uniprot ID
Q93009
Gene Name
USP7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000189 RKO Homo sapiens (Human)  1
1
EC50 = 560 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.2 nM