Brief Information of the Compound and Protein
Compound Name
3-[[7-[5-chloro-3-methyl-2-[(3S,4R)-3-methylpiperidin-4-yl]oxyphenyl]thieno[3,2-b]pyridin-2-yl]methyl]-1-(2,2,2-trifluoroethyl)pyrimidine-2,4-dione
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PubChem ID
CID: 138610213
Canonical SMILES
C[C@H]1CNCC[C@H]1Oc1c(C)cc(Cl)cc1-c1ccnc2cc(Cn3c(=O)ccn(CC(F)(F)F)c3=O)sc12
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Compound Formula C27H26ClF3N4O3S
Compound Structure
Protein Name
Ubiquitin carboxyl-terminal hydrolase 7
Protein Classification
Enzyme
>
Protease
>
Cysteine protease
>
Cysteine protease CA clan
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Cysteine protease C19 family
Uniprot ID
Q93009
Gene Name
USP7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000189 RKO Homo sapiens (Human)  1
1
EC50 = 42 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.26 nM