Brief Information of the Compound and Protein
Compound Name
3-[[7-[5-chloro-3-methyl-2-[[(2R,6R)-6-methylmorpholin-2-yl]methyl]phenyl]thieno[3,2-b]pyridin-2-yl]methyl]-3-azabicyclo[3.1.0]hexane-2,4-dione
    Show/Hide
PubChem ID
CID: 146445370
Canonical SMILES
C[C@@H]1CNC[C@@H](Cc2c(C)cc(Cl)cc2-c2ccnc3cc(CN4C(=O)C5CC5C4=O)sc23)O1
    Show/Hide
Compound Formula C26H26ClN3O3S
Compound Structure
Protein Name
Ubiquitin carboxyl-terminal hydrolase 7
Protein Classification
Enzyme
>
Protease
>
Cysteine protease
>
Cysteine protease CA clan
>
Cysteine protease C19 family
Uniprot ID
Q93009
Gene Name
USP7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000189 RKO Homo sapiens (Human)  1
1
EC50 = 60 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.39 nM