General Information of the Cell Line
Cell Line ID
CL000067
Cell Line Name
HCT 116
Synonyms
HCT-116
HCT.116
HCT_116
HCT116
HCT116wt
CoCL2
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0291
Tissue Information
Colon
Disease
Colon carcinoma (NCIt: C4910)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT00980, Aurora kinase A
 Protein Info 
Compound ID Compound Name Compound Formula
CP0032546
 Compound Info 
4-(9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-benzo[c]pyrimido[4,5-e]azepin-2-ylamino)-2-methoxybenzoic acid
   Show/Hide
C27H20ClFN4O4
  1
1
IC50 = 7 nM
 Bioactivity Info 
   TI
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CP0108599
 Compound Info 
4-[[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]benzoic acid
   Show/Hide
C26H18ClFN4O3
  1
1
IC50 = 18 nM
 Bioactivity Info 
   TI
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CP0270630
 Compound Info 
4-[[6-chloro-2-(1,3-dimethylpyrazol-4-yl)-1H-imidazo[4,5-b]pyridin-7-yl]oxy]-N-phenylbenzamide
   Show/Hide
C24H19ClN6O2
  4
1
IC50 = 27 nM
 Bioactivity Info 
   TI
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2
IC50 = 29 nM
 Bioactivity Info 
   TI
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3
IC50 = 65 nM
 Bioactivity Info 
   TI
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4
IC50 = 960 nM
 Bioactivity Info 
   TI
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CP0017774
 Compound Info 
4-[[7-[2,6-bis(fluoranyl)phenyl]-9-chloranyl-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]benzoic acid
   Show/Hide
C25H15ClF2N4O2
  3
1
IC50 = 34 nM
 Bioactivity Info 
   TI
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2
IC50 = 160 nM
 Bioactivity Info 
   TI
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3
IC50 = 310 nM
 Bioactivity Info 
   TI
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CP0075920
 Compound Info 
4-[[6-chloro-2-(1,3-dimethylpyrazol-4-yl)-1H-imidazo[4,5-b]pyridin-7-yl]oxy]-N-cyclobutylbenzamide
   Show/Hide
C22H21ClN6O2
  4
1
IC50 = 36 nM
 Bioactivity Info 
   TI
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2
IC50 = 42 nM
 Bioactivity Info 
   TI
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3
IC50 = 43 nM
 Bioactivity Info 
   TI
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4
IC50 = 2290 nM
 Bioactivity Info 
   TI
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CP0482155
 Compound Info 
1-[4-[2-[(5-chloro-6-phenylfuro[2,3-d]pyrimidin-4-yl)amino]ethyl]phenyl]-3-[3-[(dimethylamino)methyl]phenyl]urea
   Show/Hide
C30H29ClN6O2
  1
1
IC50 = 59.9 nM
 Bioactivity Info 
   TI
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CP0481968
 Compound Info 
1-[4-[2-[(5-chloro-6-phenylfuro[2,3-d]pyrimidin-4-yl)amino]ethyl]phenyl]-3-[2-[(dimethylamino)methyl]phenyl]urea
   Show/Hide
C30H29ClN6O2
  1
1
IC50 = 73.4 nM
 Bioactivity Info 
   TI
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CP0296124
 Compound Info 
4-[[6-chloro-2-(1,3-dimethylpyrazol-4-yl)-1H-imidazo[4,5-b]pyridin-7-yl]oxy]-N-(3-methyl-1,2-oxazol-5-yl)benzamide
   Show/Hide
C22H18ClN7O3
  1
1
IC50 = 95 nM
 Bioactivity Info 
   TI
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CP0476941
 Compound Info 
1-[4-[2-[(5-chloro-6-phenylfuro[2,3-d]pyrimidin-4-yl)amino]ethyl]phenyl]-3-[3-[[ethyl(methyl)amino]methyl]phenyl]urea
   Show/Hide
C31H31ClN6O2
  1
1
IC50 = 132.2 nM
 Bioactivity Info 
   TI
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CP0385532
 Compound Info 
4-[[9-chloro-7-(2-fluorophenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]benzoic acid
   Show/Hide
C25H16ClFN4O2
  1
1
IC50 = 170 nM
 Bioactivity Info 
   TI
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CP0432163
 Compound Info 
1-[4-[2-[(5-chloro-6-phenylfuro[2,3-d]pyrimidin-4-yl)amino]ethyl]phenyl]-3-phenylurea
   Show/Hide
C27H22ClN5O2
  1
1
IC50 = 389.6 nM
 Bioactivity Info 
   TI
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CP0037005
 Compound Info 
2,4-Bisanilinopyrimidine, 10
   Show/Hide
C31H31ClFN7O2
  2
1
IC50 = 390 nM
 Bioactivity Info 
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2
IC50 = 2500 nM
 Bioactivity Info 
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CP0457859
 Compound Info 
1-[4-[2-[(5-chloro-6-phenylfuro[2,3-d]pyrimidin-4-yl)amino]ethyl]phenyl]-3-[2-[(4-hydroxypiperidin-1-yl)methyl]phenyl]urea
   Show/Hide
C33H33ClN6O3
  1
1
IC50 = 1513 nM
 Bioactivity Info 
   TI
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CP0020413
 Compound Info 
2,4-Bisanilinopyrimidine, 9
   Show/Hide
C31H29ClFN7O3
  2
1
IC50 = 1600 nM
 Bioactivity Info 
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2
IC50 = 2500 nM
 Bioactivity Info 
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CP0024021
 Compound Info 
2,4-Bisanilinopyrimidine, 13
   Show/Hide
C23H17ClFN5O2
  2
1
IC50 = 1600 nM
 Bioactivity Info 
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2
IC50 = 5000 nM
 Bioactivity Info 
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CP0298941
 Compound Info 
2,4-Bisanilinopyrimidine, 5
   Show/Hide
C23H17ClFN5O2
  1
1
IC50 = 1600 nM
 Bioactivity Info 
   TI
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CP0395997
 Compound Info 
9-chloro-7-(2-fluorophenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-amine
   Show/Hide
C18H12ClFN4
  1
1
IC50 = 6000 nM
 Bioactivity Info 
   TI
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CP0253748
 Compound Info 
2,4-Bisanilinopyrimidine, 14
   Show/Hide
C20H18FN5O2
  1
1
IC50 = 6300 nM
 Bioactivity Info 
   TI
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Protein ID: PT01270, Acetyl-CoA carboxylase 1
 Protein Info 
Protein ID: PT05157, Acetyl-coenzyme A synthetase, cytoplasmic
 Protein Info 
Protein ID: PT02692, Aldo-keto reductase family 1 member C3
 Protein Info 
Protein ID: PT00883, Angiopoietin-1 receptor
 Protein Info 
Protein ID: PT03639, ATPase family AAA domain-containing protein 2
 Protein Info 
Protein ID: PT01223, Aurora kinase B
 Protein Info 
Protein ID: PT02995, Bromodomain and PHD finger-containing protein 1
 Protein Info 
Protein ID: PT02593, Bromodomain-containing protein 1
 Protein Info 
Protein ID: PT01462, Bromodomain-containing protein 4
 Protein Info 
Protein ID: PT01210, Casein kinase II subunit alpha
 Protein Info 
Protein ID: PT00985, Cell division cycle 7-related protein kinase
 Protein Info 
Protein ID: PT03225, Cellular tumor antigen p53
 Protein Info 
Protein ID: PT01975, Cyclin-dependent kinase 8
 Protein Info 
Protein ID: PT01235, Cyclin-dependent kinase 9
 Protein Info 
Protein ID: PT01348, Dual specificity protein kinase TTK
 Protein Info 
Protein ID: PT00922, Epidermal growth factor receptor
 Protein Info 
Protein ID: PT01080, ERK activator kinase 1
 Protein Info 
Protein ID: PT03462, GTPase KRas
 Protein Info 
Protein ID: PT01566, Histone-lysine N-methyltransferase EHMT2
 Protein Info 
Protein ID: PT02791, Hypoxia-inducible factor 1-alpha
 Protein Info 
Protein ID: PT02997, Isocitrate dehydrogenase [NADP] cytoplasmic
 Protein Info 
Protein ID: PT03648, Isocitrate dehydrogenase [NADP], mitochondrial
 Protein Info 
Protein ID: PT01160, Kinesin-like protein KIF11
 Protein Info 
Protein ID: PT00911, Melanocyte-stimulating hormone receptor
 Protein Info 
Protein ID: PT01164, Mitogen-activated protein kinase kinase kinase 7
 Protein Info 
Protein ID: PT00838, NAD(P)H dehydrogenase [quinone] 1
 Protein Info 
Protein ID: PT01045, Phosphoinositide 3-kinase alpha
 Protein Info 
Protein ID: PT00844, Platelet-derived growth factor receptor beta
 Protein Info 
Protein ID: PT03087, Protein arginine N-methyltransferase 5
 Protein Info 
Protein ID: PT03001, S-adenosylmethionine synthase isoform type-2
 Protein Info 
Protein ID: PT01934, Serine/threonine-protein kinase ATR
 Protein Info 
Protein ID: PT01466, Telomerase reverse transcriptase
 Protein Info 
Protein ID: PT02000, TRAF2 and NCK-interacting protein kinase
 Protein Info 
Protein ID: PT03307, Transcription initiation factor TFIID subunit 1
 Protein Info 
Protein ID: PT01640, Transketolase
 Protein Info 
Protein ID: PT00925, Vascular endothelial growth factor receptor 3
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0001157
 Compound Info 
N-[5-[4-[2-(dimethylamino)ethylamino]quinazolin-6-yl]-2-methoxypyridin-3-yl]butane-1-sulfonamide
   Show/Hide
 C22H30N6O3S  1
1
IC50 = 160 nM
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CP0001250
 Compound Info 
(16E)-14-methyl-20-oxa-5,7,14,27-tetrazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(25),2(27),3,5,8,10,12(26),16,21,23-decaene
   Show/Hide
 C23H24N4O  1
1
IC50 = 79 nM
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CP0001865
 Compound Info 
(5R,8S,11S)-5-methyl-8-propan-2-yl-11-[(E)-4-(2-sulfanylethylsulfanyl)but-1-enyl]-10-oxa-3,17-dithia-7,14,19,20-tetrazatricyclo[14.2.1.12,5]icosa-1(18),2(20),16(19)-triene-6,9,13-trione
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 C23H32N4O4S4  1
1
IC50 = 1500 nM
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CP0002778
 Compound Info 
4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
   Show/Hide
 C29H31N7O  1
1
IC50 = 10000 nM
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CP0003147
 Compound Info 
ethyl 6-[5-(benzenesulfonamido)pyridin-3-yl]imidazo[1,2-a]pyridine-3-carboxylate
   Show/Hide
 C21H18N4O4S  1
1
IC50 = 540 nM
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CP0003433
 Compound Info 
(Arylindolyl)maleimide deriv. 27
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 C21H16N4O2  1
1
LC50 > 100000 nM
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CP0003832
 Compound Info 
N'-hydroxy-N-phenyloctanediamide
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 C14H20N2O3  6
1
CC50 = 1000 nM
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2
IC50 = 310 nM
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3
IC50 = 700 nM
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4
IC50 = 1310 nM
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5
IC50 = 1400 nM
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6
IC50 = 1900 nM
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CP0004620
 Compound Info 
(R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butylboronic acid
   Show/Hide
 C19H25BN4O4  1
1
IC50 = 1.4 nM
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CP0004959
 Compound Info 
S-[(E)-4-[(5R,8S,11S)-5-methyl-6,9,13-trioxo-8-propan-2-yl-10-oxa-3,17-dithia-7,14,19,20-tetrazatricyclo[14.2.1.12,5]icosa-1(18),2(20),16(19)-trien-11-yl]but-3-enyl] octanethioate
   Show/Hide
 C29H42N4O5S3  1
1
IC50 = 44 nM
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CP0005479
 Compound Info 
CHEBI:46024
   Show/Hide
 C17H22N2O3  1
1
EC50 = 1000 nM
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CP0006321
 Compound Info 
PLX-4032
   Show/Hide
 C23H18ClF2N3O3S  1
1
IC50 > 10000 nM
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CP0006369
 Compound Info 
6-[3-[4-[1-(5-cyanopentyl)indol-3-yl]-1-hydroxy-2,5-dioxopyrrol-3-yl]indol-1-yl]hexanenitrile
   Show/Hide
 C32H31N5O3  1
1
GI50 = 4170 nM
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CP0007430
 Compound Info 
IBRUTINIB
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 C25H24N6O2  1
1
GI50 > 10000 nM
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CP0007711
 Compound Info 
(E)-3-[4-[[2-(2-methyl-1H-indol-3-yl)ethylamino]methyl]phenyl]-N'-propylprop-2-enehydrazide;2,2,2-trifluoroacetic acid
   Show/Hide
 C26H31F3N4O3  1
1
GI50 = 22.9 nM
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CP0007715
 Compound Info 
S-[(Z)-4-fluoro-4-[(5R,8S,11S)-5-methyl-6,9,13-trioxo-8-propan-2-yl-10-oxa-3,17-dithia-7,14,19,20-tetrazatricyclo[14.2.1.12,5]icosa-1(18),2(20),16(19)-trien-11-yl]but-3-enyl] octanethioate
   Show/Hide
 C29H41FN4O5S3  1
1
IC50 = 810 nM
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CP0007846
 Compound Info 
N-hydroxy-4-[(2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)methyl]benzamide
   Show/Hide
 C20H21N3O2  1
1
GI50 > 5000 nM
   TI
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CP0011853
 Compound Info 
N-(2-aminophenyl)-8-[[(2E)-3-(3-bromo-4-hydroxyphenyl)-2-hydroxyiminopropanoyl]amino]octanamide
   Show/Hide
 C23H29BrN4O4  1
1
IG50 = 11900 nM
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CP0013140
 Compound Info 
N-hydroxy-7-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]heptanamide
   Show/Hide
 C16H20N6O2  1
1
IC50 = 2320 nM
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CP0014425
 Compound Info 
4-[[3-[(dimethylamino)methyl]indol-1-yl]methyl]-N-hydroxybenzamide
   Show/Hide
 C19H21N3O2  1
1
GI50 > 5000 nM
   TI
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CP0016093
 Compound Info 
(5-(1-benzyl-1H-indazol-3-yl)furan-2-yl)methanol
   Show/Hide
 C19H16N2O2  1
1
IC50 = 2200 nM
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CP0017774
 Compound Info 
4-[[7-[2,6-bis(fluoranyl)phenyl]-9-chloranyl-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]benzoic acid
   Show/Hide
 C25H15ClF2N4O2  1
1
IC50 = 180 nM
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CP0018039
 Compound Info 
N-[4-[4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]sulfanylphenyl]cyclopropanecarboxamide
   Show/Hide
 C23H28N8OS  1
1
IC50 = 28 nM
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CP0019439
 Compound Info 
8-[3-(1-benzofuran-2-yl)-5-chloropyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one
   Show/Hide
 C21H20ClN3O2  1
1
GI50 = 40550 nM
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CP0020306
 Compound Info 
N-[2-chloro-4-(1-methylpyrazol-4-yl)phenyl]-2-(1-methylpyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-amine
   Show/Hide
 C21H18ClN7  1
1
GI50 = 4600 nM
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CP0020413
 Compound Info 
2,4-Bisanilinopyrimidine, 9
   Show/Hide
 C31H29ClFN7O3  1
1
IC50 = 640 nM
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CP0020468
 Compound Info 
tert-butyl 6-[2-chloro-4-(1-methylpyrazol-3-yl)anilino]-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
   Show/Hide
 C26H26ClN7O2  1
1
GI50 = 4400 nM
   TI
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CP0023441
 Compound Info 
tert-butyl 6-[2-chloro-4-(dimethylcarbamoyl)anilino]-2-(1,3-oxazol-5-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
   Show/Hide
 C24H24ClN5O4  1
1
GI50 = 4200 nM
   TI
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CP0023555
 Compound Info 
4-[(2,6-dimethoxybenzoyl)amino]-N-[1-[3-[[(E)-4-(dimethylamino)but-2-enoyl]amino]phenyl]sulfonylpiperidin-4-yl]-1H-pyrazole-5-carboxamide;2,2,2-trifluoroacetic acid
   Show/Hide
 C32H38F3N7O9S  1
1
IC50 = 4100 nM
   TI
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CP0023705
 Compound Info 
4-[[4-amino-6-(tert-butylamino)-5-cyanopyridin-2-yl]amino]benzamide
   Show/Hide
 C17H20N6O  1
1
GI50 = 1600 nM
   TI
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CP0024754
 Compound Info 
tert-butyl 6-[2-chloro-4-(4-methoxypiperidine-1-carbonyl)anilino]-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
   Show/Hide
 C29H33ClN6O4  1
1
GI50 = 3000 nM
   TI
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CP0026134
 Compound Info 
N-[4-(6,7-dimethoxyquinolin-4-yl)oxy-3-fluorophenyl]-2-oxo-3-phenylimidazolidine-1-carboxamide
   Show/Hide
 C27H23FN4O5  1
1
IC50 = 300 nM
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CP0026977
 Compound Info 
SB-590885
   Show/Hide
 C27H27N5O2  1
1
EC50 = 1100 nM
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CP0027579
 Compound Info 
N-(2,6-diethylphenyl)-1-methyl-8-[4-[(1-methylpiperidin-4-yl)carbamoyl]-2-(trifluoromethoxy)anilino]-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamide
   Show/Hide
 C35H39F3N8O3  1
1
GI50 = 180 nM
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CP0029575
 Compound Info 
4-[(2,6-dichlorobenzoyl)amino]-N-[1-[[3-(propanoylamino)phenyl]methyl]piperidin-4-yl]-1H-pyrazole-5-carboxamide;2,2,2-trifluoroacetic acid
   Show/Hide
 C28H29Cl2F3N6O5  1
1
IC50 = 123 nM
   TI
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CP0030351
 Compound Info 
tert-butyl 6-[2-chloro-4-[4-(dimethylamino)piperidine-1-carbonyl]anilino]-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
   Show/Hide
 C30H36ClN7O3  1
1
GI50 = 2000 nM
   TI
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CP0030809
 Compound Info 
tert-butyl 6-[2-chloro-4-(3-methylimidazol-4-yl)anilino]-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
   Show/Hide
 C26H26ClN7O2  1
1
GI50 = 160 nM
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CP0032508
 Compound Info 
N-[1-[3-(prop-2-enoylamino)phenyl]sulfonylpiperidin-4-yl]-4-[(2,4,6-trimethoxybenzoyl)amino]-1H-pyrazole-5-carboxamide;2,2,2-trifluoroacetic acid
   Show/Hide
 C30H33F3N6O10S  1
1
IC50 > 10000 nM
   TI
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CP0034077
 Compound Info 
4-[(2,6-dichlorobenzoyl)amino]-N-[1-[3-(prop-2-enoylamino)benzoyl]piperidin-4-yl]-1H-pyrazole-5-carboxamide;2,2,2-trifluoroacetic acid
   Show/Hide
 C28H25Cl2F3N6O6  1
1
IC50 = 32 nM
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CP0037005
 Compound Info 
2,4-Bisanilinopyrimidine, 10
   Show/Hide
 C31H31ClFN7O2  1
1
IC50 = 190 nM
   TI
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CP0037780
 Compound Info 
(2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanamido]-4-methylpentanoic acid
   Show/Hide
 C16H24N2O4  1
1
IC50 > 500000 nM
   TI
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   TS
CP0038703
 Compound Info 
6-{3-[2-Butyl-1-(2-pyrrolidin-1-yl-ethyl)-1H-benzimidazole-5-carbonyl]-ureido}-hexanoic acidhydroxyamide
   Show/Hide
 C25H38N6O4  1
1
IC50 = 3520 nM
   TI
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   TS
CP0039077
 Compound Info 
(2R)-2-amino-3-{[(4-methoxyphenyl)diphenylmethyl]sulfanyl}propanoic acid
   Show/Hide
 C23H23NO3S  1
1
GI50 = 130 nM
   TI
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CP0041513
 Compound Info 
(E)-3-[4-(3,4-Dimethoxy-benzenesulfonylamino)-phenyl]-N-hydroxy-acrylamide
   Show/Hide
 C17H18N2O6S  1
1
EC50 = 200 nM
   TI
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   TS
CP0043162
 Compound Info 
(4S,5S,6S)-6-{(R)-Carbamoyl-[(2S,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-hydroxy-3-methoxy-tetrahydro-furan-2-yl]-methoxy}-4,5-dihydroxy-5,6-dihydro-4H-pyran-2-carboxylic acid ((S)-2-oxo-azepan-3-yl)-amide
   Show/Hide
 C23H31N5O12  1
1
IC50 > 50000 nM
   TI
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CP0044706
 Compound Info 
(2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl}phenyl)prop-2-enamide
   Show/Hide
 C22H25N3O3  1
1
IC50 = 13 nM
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CP0046275
 Compound Info 
2-cyclohexyl-6-methoxy-N-(1-propan-2-ylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine
   Show/Hide
 C30H47N5O2  1
1
EC50 = 11000 nM
   TI
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CP0046759
 Compound Info 
N-[3-fluoro-4-[2-(1-methylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-1-phenyl-5-(trifluoromethyl)pyrazole-4-carboxamide
   Show/Hide
 C28H18F4N6O2S  1
1
IC50 = 80 nM
   TI
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CP0047412
 Compound Info 
2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl)-1-(2-chlorophenyl)-1H-pyrazol-3-yl)-5-tert-butyl-1,3,4-thiadiazole
   Show/Hide
 C24H21BrClN7S  1
1
EC50 > 100000 nM
   TI
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CP0048624
 Compound Info 
(E)-3-(4-Benzenesulfonylamino-phenyl)-N-hydroxy-acrylamide
   Show/Hide
 C15H14N2O4S  1
1
EC50 = 3000 nM
   TI
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CP0050427
 Compound Info 
3-amino-6-(4-((1-(dimethylamino)propan-2-yl)sulfonyl)-phenyl)-N-phenylpyrazine-2-carboxamide
   Show/Hide
 C22H25N5O3S  1
1
IC50 = 1100 nM
   TI
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CP0050838
 Compound Info 
(E)-3-[4-(4-Chloro-benzenesulfonylamino)-phenyl]-N-hydroxy-acrylamide
   Show/Hide
 C15H13ClN2O4S  1
1
EC50 = 1000 nM
   TI
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CP0050840
 Compound Info 
4-(4-Benzenesulfonylamino-phenyl)-N-hydroxy-butyramide
   Show/Hide
 C16H18N2O4S  1
1
EC50 = 8000 nM
   TI
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   TS
CP0060320
 Compound Info 
(2E,4E)-N-hydroxy-5-[4-(4-methoxyphenyl)phenyl]penta-2,4-dienamide
   Show/Hide
 C18H17NO3  1
1
IC50 = 2400 nM
   TI
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CP0060330
 Compound Info 
(E)-N-hydroxy-3-[4-(4-hydroxyphenyl)phenyl]prop-2-enamide
   Show/Hide
 C15H13NO3  1
1
IC50 = 330 nM
   TI
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CP0060763
 Compound Info 
7-[6-(4-aminophenyl)-4-morpholin-4-ylpyrazolo[3,4-d]pyrimidin-1-yl]-N-hydroxyheptanamide
   Show/Hide
 C22H29N7O3  1
1
IC50 = 7.1 nM
   TI
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CP0061532
 Compound Info 
3-(4-Benzenesulfonylamino-phenyl)-N-hydroxy-2-methyl-propionamide
   Show/Hide
 C16H18N2O4S  1
1
EC50 > 50000 nM
   TI
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CP0061813
 Compound Info 
N-ethoxy-4-(2-fluoro-4-iodoanilino)-1H-indazole-5-carboxamide
   Show/Hide
 C16H14FIN4O2  1
1
EC50 = 132 nM
   TI
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CP0063755
 Compound Info 
6-[4-(Trifluoromethyl)phenyl]-3,4-dihydro-2(1H)-quinolinone
   Show/Hide
 C16H12F3NO  6
1
IC50 = 0.45 nM
   TI
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2
IC50 = 0.83 nM
   TI
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3
IC50 = 6.9 nM
   TI
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4
IC50 = 36 nM
   TI
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5
IC50 = 162 nM
   TI
   LI
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   TS
6
IC50 = 2090 nM
   TI
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   TS
CP0064630
 Compound Info 
N-(2-amino-5-thiophen-2-ylphenyl)-6-(2,8-diazaspiro[4.5]decan-8-yl)pyridine-3-carboxamide
   Show/Hide
 C24H27N5OS  1
1
GI50 = 93 nM
   TI
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CP0065009
 Compound Info 
(E)-N-Hydroxy-3-[4-(4-methoxy-benzenesulfonylamino)-phenyl]-acrylamide
   Show/Hide
 C16H16N2O5S  1
1
EC50 = 400 nM
   TI
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CP0066337
 Compound Info 
N-(3-aminopropyl)-N-[(1R)-1-(3-benzyl-7-chloro-4-oxochromen-2-yl)-2-methylpropyl]-4-methylbenzamide
   Show/Hide
 C31H33ClN2O3  1
1
GI50 = 9.7 nM
   TI
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CP0068848
 Compound Info 
(5S,8S,10aR)-N-benzhydryl-5-[[(2S)-2-(methylamino)propanoyl]amino]-3-(3-methylbutanoyl)-6-oxo-1,2,4,5,8,9,10,10a-octahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide
   Show/Hide
 C32H43N5O4  1
1
EC50 > 10000 nM
   TI
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CP0069210
 Compound Info 
US8569511, 1
   Show/Hide
 C22H20F2N6O2  1
1
IC50 = 1350 nM
   TI
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CP0077992
 Compound Info 
[4-(3-chloro-4-fluoroanilino)thieno[2,3-d]pyrimidin-6-yl]-(5-hydroxy-1H-indol-2-yl)methanone
   Show/Hide
 C21H12ClFN4O2S  1
1
IC50 = 7690 nM
   TI
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CP0080932
 Compound Info 
5-[6-[6-(propan-2-ylamino)indazol-1-yl]pyrazin-2-yl]pyridine-2-carboxylic acid
   Show/Hide
 C20H18N6O2  1
1
IC50 = 12100 nM
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CP0082019
 Compound Info 
(2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoic acid
   Show/Hide
 C22H21NO2S  1
1
GI50 = 500 nM
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CP0086044
 Compound Info 
(E)-N-hydroxy-3-(4-phenylphenyl)prop-2-enamide
   Show/Hide
 C15H13NO2  1
1
IC50 = 1580 nM
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CP0086325
 Compound Info 
2-amino-5-(3,4-dimethylphenyl)-5,5-diphenylpentanoic acid
   Show/Hide
 C25H27NO2  1
1
GI50 = 28 nM
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CP0086475
 Compound Info 
2-[(4-methoxyphenyl)-diphenylmethyl]sulfanylethanamine
   Show/Hide
 C22H23NOS  1
1
GI50 = 40 nM
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CP0091390
 Compound Info 
pyridin-3-ylmethyl N-[[4-[(2-amino-5-phenylphenyl)carbamoyl]phenyl]methyl]carbamate
   Show/Hide
 C27H24N4O3  1
1
GI50 = 225 nM
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CP0092039
 Compound Info 
(7-methoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamine
   Show/Hide
 C17H15N3O  1
1
IC50 = 1500 nM
   TI
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CP0095776
 Compound Info 
4-Benzenesulfonylamino-N-hydroxy-benzamide
   Show/Hide
 C13H12N2O4S  1
1
EC50 = 2000 nM
   TI
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CP0103411
 Compound Info 
N-(2-aminophenyl)-4-[[(6-methoxy-1,3-benzothiazol-2-yl)amino]methyl]benzamide
   Show/Hide
 C22H20N4O2S  1
1
IC50 = 200 nM
   TI
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CP0106940
 Compound Info 
6-[3-(4-Bromo-benzoyl)-ureido]-hexanoic acid hydroxyamide
   Show/Hide
 C14H18BrN3O4  1
1
IC50 = 600 nM
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CP0107761
 Compound Info 
1-[4-[2-[[6-[4-[2-(dibutylamino)ethoxy]phenyl]furo[2,3-d]pyrimidin-4-yl]amino]ethyl]phenyl]-3-phenylurea
   Show/Hide
 C37H44N6O3  1
1
EC50 = 293 nM
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CP0111689
 Compound Info 
(E)-N-hydroxy-3-[6-(4-methoxyphenoxy)quinolin-2-yl]prop-2-enamide
   Show/Hide
 C19H16N2O4  1
1
GI50 = 1820 nM
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CP0112599
 Compound Info 
US8569511, 2
   Show/Hide
 C23H22F2N6O2  1
1
IC50 = 692 nM
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CP0113283
 Compound Info 
2-(4-Benzenesulfonylamino-benzyl)-N-hydroxy-3-methyl-butyramide
   Show/Hide
 C18H22N2O4S  1
1
EC50 = 30000 nM
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CP0113988
 Compound Info 
CEP-32496
   Show/Hide
 C24H22F3N5O5  1
1
EC50 = 669 nM
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CP0114427
 Compound Info 
2-(4-Benzenesulfonylamino-phenyl)-N-hydroxy-acetamide
   Show/Hide
 C14H14N2O4S  1
1
EC50 = 22000 nM
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CP0115603
 Compound Info 
2-[3-[6-[5-[(2,4-difluorophenyl)sulfonylamino]-6-methoxypyridin-3-yl]-4-methylquinazolin-8-yl]oxypropyl-methylamino]-N-hydroxypyrimidine-5-carboxamide
   Show/Hide
 C30H28F2N8O6S  1
1
IC50 = 2900 nM
   TI
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CP0120732
 Compound Info 
2-[3-(2,2-dimethylpropanoyl)pyrrolidin-1-yl]-N-[4-[4-[(5-methyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]sulfanylphenyl]acetamide
   Show/Hide
 C27H32N8O2S  1
1
IC50 = 12.5 nM
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CP0130031
 Compound Info 
(4-benzylphenyl)-[1-(2-fluoro-5-hydroxybenzoyl)piperidin-4-yl]methanone
   Show/Hide
 C26H24FNO3  1
1
IC50 = 17000 nM
   TI
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CP0130732
 Compound Info 
3-(cyclohexen-1-yl)-6-(4-methoxyphenyl)-2-phenyl-5-(pyridin-2-ylamino)-1H-pyrazolo[1,5-a]pyrimidin-7-one
   Show/Hide
 C30H27N5O2  1
1
IC50 = 257 nM
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CP0135449
 Compound Info 
(E)-N-Hydroxy-3-[4-(4-sulfamoyl-benzenesulfonylamino)-phenyl]-acrylamide
   Show/Hide
 C15H15N3O6S2  1
1
EC50 > 42000 nM
   TI
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CP0137418
 Compound Info 
N-[4-[2-(1-ethylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-3-(4-fluorophenyl)-2-oxoimidazolidine-1-carboxamide
   Show/Hide
 C28H22F2N6O3S  1
1
IC50 = 13000 nM
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CP0139017
 Compound Info 
2-[10-(2-methoxyethyl)-13-oxa-3,4,6,7,10-pentazatricyclo[7.4.0.02,6]trideca-1(9),2,4,7-tetraen-5-yl]-N-(piperidin-4-ylmethyl)quinolin-8-amine
   Show/Hide
 C25H30N8O2  1
1
GI50 = 21200 nM
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CP0139226
 Compound Info 
(2E,4E)-N-hydroxy-5-(4-phenylphenyl)penta-2,4-dienamide
   Show/Hide
 C17H15NO2  1
1
IC50 = 980 nM
   TI
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CP0144077
 Compound Info 
(E)-N-Hydroxy-3-[4-(toluene-4-sulfonylamino)-phenyl]-acrylamide
   Show/Hide
 C16H16N2O4S  1
1
EC50 = 700 nM
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CP0148039
 Compound Info 
(E)-3-[4-(Benzenesulfonyl-methyl-amino)-phenyl]-N-hydroxy-acrylamide
   Show/Hide
 C16H16N2O4S  1
1
EC50 = 4000 nM
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CP0155651
 Compound Info 
N-(2-aminophenyl)-4-[(6-methoxy-1H-benzimidazol-2-yl)sulfanylmethyl]benzamide
   Show/Hide
 C22H20N4O2S  1
1
IC50 = 200 nM
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CP0156012
 Compound Info 
4-(4-methoxyphenyl)-4,4-diphenylbutan-1-amine
   Show/Hide
 C23H25NO  1
1
GI50 = 33 nM
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CP0160241
 Compound Info 
2-[(3R)-3-[2-(4-methylpiperazin-1-yl)ethoxy]pyrrolidin-1-yl]-N-[4-[4-[(5-methyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]sulfanylphenyl]acetamide
   Show/Hide
 C29H38N10O2S  1
1
IC50 = 29.8 nM
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CP0161295
 Compound Info 
N-(2-aminophenyl)-4-{3-chloro-5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl}benzamide
   Show/Hide
 C25H28ClN5O  1
1
IC50 = 338.84 nM
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CP0170825
 Compound Info 
(E)-3-[4-(4-tert-Butyl-benzenesulfonylamino)-phenyl]-N-hydroxy-acrylamide
   Show/Hide
 C19H22N2O4S  1
1
EC50 = 800 nM
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CP0171242
 Compound Info 
(6-methoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamine
   Show/Hide
 C17H15N3O  1
1
IC50 < 100 nM
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CP0175569
 Compound Info 
N-[1-[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]-2,3-dihydroindol-6-yl]acetamide
   Show/Hide
 C20H19N7O  1
1
GI50 = 530 nM
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CP0176598
 Compound Info 
N-[4-[2-[(2S,3S,5R)-2-[[tert-butyl(dimethyl)silyl]oxymethyl]-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl]-1,3-dithian-2-yl]phenyl]-N'-hydroxyoctanediamide
   Show/Hide
 C34H52N4O7S2Si  2
1
GI50 = 3388.44 nM
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2
GI50 = 3390 nM
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CP0178025
 Compound Info 
2-[(3R)-3-(3,3-difluoropyrrolidine-1-carbonyl)pyrrolidin-1-yl]-N-[4-[4-[(5-methyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]sulfanylphenyl]acetamide
   Show/Hide
 C27H29F2N9O2S  1
1
IC50 = 1.2 nM
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CP0179315
 Compound Info 
N-(2-aminophenyl)-4-(3-methyl-5-{[4-(propan-2-yl)piperazin-1-yl]methyl}pyridin-2-yl)benzamide
   Show/Hide
 C27H33N5O  1
1
IC50 = 239.88 nM
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CP0180529
 Compound Info 
2-[(3S,4S)-3-(4-fluorophenoxy)-4-hydroxypyrrolidin-1-yl]-N-[4-[4-[(5-methyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]sulfanylphenyl]acetamide
   Show/Hide
 C28H27FN8O3S  1
1
IC50 = 5 nM
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CP0184260
 Compound Info 
N-[2-(4-bromophenyl)ethyl]-5-[(2,5-dihydroxyphenyl)methylamino]-2-hydroxybenzamide
   Show/Hide
 C22H21BrN2O4  1
1
GI50 = 7600 nM
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CP0184863
 Compound Info 
US9018214, 63
   Show/Hide
 C25H34N4O2  1
1
EC50 > 10000 nM
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CP0185307
 Compound Info 
4-hydroxybenzo[a]pyrrolo[3,4-c]carbazole-1,3(2H,8H)-dione
   Show/Hide
 C18H10N2O3  1
1
IC50 = 17500 nM
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CP0190732
 Compound Info 
N-[5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-[2-(dimethylamino)ethyl-methylamino]phenyl]acetamide
   Show/Hide
 C23H29N9O  1
1
GI50 = 30 nM
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CP0192280
 Compound Info 
(E)-N-Hydroxy-3-[4-(4-nitro-benzenesulfonylamino)-phenyl]-acrylamide
   Show/Hide
 C15H13N3O6S  1
1
EC50 = 6000 nM
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CP0194921
 Compound Info 
5-(2,5-Dihydroxy-benzylamino)-2-hydroxy-N-[2-(4-methoxy-phenyl)-ethyl]-benzamide
   Show/Hide
 C23H24N2O5  1
1
GI50 = 23000 nM
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CP0197800
 Compound Info 
3-[5-(Trifluoroacetyl)thiophen-2-yl]benzoic Acid
   Show/Hide
 C13H7F3O3S  1
1
EC50 > 50000 nM
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CP0200676
 Compound Info 
N-(2-aminophenyl)-4-[4-[(E)-3-(4-methylphenyl)prop-2-enoyl]piperazin-1-yl]benzamide
   Show/Hide
 C27H28N4O2  1
1
IC50 = 69 nM
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CP0200998
 Compound Info 
N-(2-aminophenyl)-4-[(2,4-dioxo-1H-quinazolin-3-yl)methyl]benzamide
   Show/Hide
 C22H18N4O3  1
1
IC50 = 800 nM
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CP0202162
 Compound Info 
N-(2-aminophenyl)-4-[[6-(pyridin-2-ylmethylamino)-1,3-benzothiazol-2-yl]sulfanylmethyl]benzamide
   Show/Hide
 C27H23N5OS2  1
1
IC50 = 1000 nM
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CP0202163
 Compound Info 
N-(2-aminophenyl)-4-[[6-(pyridin-3-ylmethylamino)-1,3-benzothiazol-2-yl]sulfanylmethyl]benzamide
   Show/Hide
 C27H23N5OS2  1
1
IC50 = 1000 nM
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CP0203398
 Compound Info 
2-[(3S,4S)-3-hydroxy-4-(2-methoxyethoxy)pyrrolidin-1-yl]-N-[4-[4-[(5-methyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]sulfanylphenyl]acetamide
   Show/Hide
 C25H30N8O4S  1
1
IC50 = 25 nM
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CP0203402
 Compound Info 
2-[(2S,4R)-4-hydroxy-2-(hydroxymethyl)pyrrolidin-1-yl]-N-[4-[4-[(5-methyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]sulfanylphenyl]acetamide
   Show/Hide
 C23H26N8O3S  1
1
IC50 = 596 nM
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CP0203408
 Compound Info 
2-[(2S,4S)-4-fluoro-2-(hydroxymethyl)pyrrolidin-1-yl]-N-[4-[4-[(5-methyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]sulfanylphenyl]acetamide
   Show/Hide
 C23H25FN8O2S  1
1
IC50 = 25 nM
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CP0203409
 Compound Info 
2-[(2S,4R)-4-fluoro-2-(hydroxymethyl)pyrrolidin-1-yl]-N-[4-[4-[(5-methyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]sulfanylphenyl]acetamide
   Show/Hide
 C23H25FN8O2S  1
1
IC50 = 104 nM
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CP0204175
 Compound Info 
(E)-N-hydroxy-3-[3-(4-hydroxyphenyl)phenyl]prop-2-enamide
   Show/Hide
 C15H13NO3  1
1
IC50 = 1640 nM
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CP0204863
 Compound Info 
(E)-N-hydroxy-3-(4-((4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenylamino)methyl)phenyl)acrylamide
   Show/Hide
 C26H24N6O2  1
1
IC50 = 1260 nM
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CP0205696
 Compound Info 
N-(2-aminophenyl)-4-(1-{[4-(methylcarbamoyl)phenyl]methyl}piperidin-4-yl)benzamide
   Show/Hide
 C27H30N4O2  1
1
IC50 = 436.52 nM
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CP0205738
 Compound Info 
N-(2-aminophenyl)-4-[5-(azetidin-1-ylmethyl)-3-fluoropyridin-2-yl]benzamide
   Show/Hide
 C22H21FN4O  1
1
IC50 = 371.54 nM
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CP0208474
 Compound Info 
N-(2-aminophenyl)-6-(2-oxo-1-oxa-3,8-diazaspiro[4.5]decan-8-yl)pyridine-3-carboxamide
   Show/Hide
 C19H21N5O3  1
1
GI50 = 5080 nM
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CP0208829
 Compound Info 
N-(2-aminophenyl)-4-(3-cyano-5-{[4-(propan-2-yl)piperazin-1-yl]methyl}pyridin-2-yl)benzamide
   Show/Hide
 C27H30N6O  1
1
IC50 = 141.25 nM
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CP0212776
 Compound Info 
5-(2,5-Dihydroxy-benzylamino)-2-hydroxy-N-phenethyl-benzamide
   Show/Hide
 C22H22N2O4  1
1
GI50 = 18000 nM
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CP0214010
 Compound Info 
3-(4-Benzenesulfonylamino-phenyl)-N-hydroxy-propionamide
   Show/Hide
 C15H16N2O4S  1
1
EC50 = 2000 nM
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CP0217425
 Compound Info 
(E)-N-Hydroxy-3-[4-(toluene-3-sulfonylamino)-phenyl]-acrylamide
   Show/Hide
 C16H16N2O4S  1
1
EC50 = 300 nM
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CP0225552
 Compound Info 
(5-methoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamine
   Show/Hide
 C17H15N3O  1
1
IC50 = 2300 nM
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CP0228509
 Compound Info 
7-[(6-chloroquinazolin-4-yl)amino]-N-hydroxyheptanamide
   Show/Hide
 C15H19ClN4O2  1
1
IC50 = 2110 nM
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CP0229968
 Compound Info 
[1-(2,4-difluoro-5-hydroxybenzoyl)piperidin-4-yl]-(4-phenylsulfanylphenyl)methanone
   Show/Hide
 C25H21F2NO3S  1
1
IC50 = 15000 nM
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CP0230489
 Compound Info 
CHEMBL4763626
   Show/Hide
 C18H16ClN5O5  1
1
IC50 = 302 nM
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CP0231885
 Compound Info 
1-[(2R,4S,5S)-5-[[tert-butyl(dimethyl)silyl]oxymethyl]-4-[2-(3,4-dimethoxyphenyl)-1,3-dithian-2-yl]oxolan-2-yl]-5-methylpyrimidine-2,4-dione
   Show/Hide
 C28H42N2O6S2Si  1
1
GI50 = 3630 nM
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CP0232138
 Compound Info 
N-[4-[4-[(5-methyl-1H-pyrazol-3-yl)amino]-6-[(2-morpholin-4-ylacetyl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]sulfanylphenyl]cyclopropanecarboxamide
   Show/Hide
 C26H29N9O3S  1
1
IC50 = 160 nM
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CP0246368
 Compound Info 
2-[(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyl-1-[(2S)-1-[(2-methylpropan-2-yl)oxy]-1-oxobutan-2-yl]-2-oxopiperidin-3-yl]acetic acid
   Show/Hide
 C28H33Cl2NO5  1
1
IC50 > 25000 nM
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CP0248465
 Compound Info 
2-[(2S,4R)-4-amino-2-(hydroxymethyl)pyrrolidin-1-yl]-N-[4-[4-[(5-methyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]sulfanylphenyl]acetamide
   Show/Hide
 C23H27N9O2S  1
1
IC50 = 4700 nM
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CP0248466
 Compound Info 
2-[(2R,4R)-2-(hydroxymethyl)-4-[(2-methylpropan-2-yl)oxy]pyrrolidin-1-yl]-N-[4-[4-[(5-methyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]sulfanylphenyl]acetamide
   Show/Hide
 C27H34N8O3S  1
1
IC50 = 2390 nM
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CP0249179
 Compound Info 
5-[(3S)-4-(5-bromopyridine-2-carbonyl)-3-(4-chlorophenyl)piperazine-1-carbonyl]-1-phenyl-3-[3-(trifluoromethyl)phenyl]pyridin-2-one
   Show/Hide
 C35H25BrClF3N4O3  1
1
GI50 = 1180 nM
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CP0250629
 Compound Info 
(2R)-2-amino-3-[(3,4-dimethylphenyl)-diphenylmethyl]sulfanylpropanoic acid
   Show/Hide
 C24H25NO2S  1
1
GI50 = 63 nM
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CP0254570
 Compound Info 
2-[(4-fluorophenyl)methyl-[8-(hydroxyamino)-8-oxooctyl]amino]-N-(3-imidazol-1-ylpropyl)-1,3-thiazole-5-carboxamide
   Show/Hide
 C25H33FN6O3S  1
1
IC50 = 63000 nM
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CP0254571
 Compound Info 
3-chloro-4-[6-[6-(propan-2-ylamino)indazol-1-yl]pyrazin-2-yl]benzoic acid
   Show/Hide
 C21H18ClN5O2  1
1
IC50 = 11800 nM
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CP0255607
 Compound Info 
2-[(3S,4S)-3-hydroxy-4-(2-methylbutan-2-yloxy)pyrrolidin-1-yl]-N-[4-[4-[(5-methyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]sulfanylphenyl]acetamide
   Show/Hide
 C27H34N8O3S  1
1
IC50 = 9 nM
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CP0255608
 Compound Info 
2-(dimethylamino)-N-[4-[4-[(5-methyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]sulfanylphenyl]acetamide
   Show/Hide
 C20H22N8OS  1
1
IC50 = 370 nM
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CP0256640
 Compound Info 
N-[4-[4-[(5-methyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]sulfanylphenyl]-2-[(3R)-3-(3-morpholin-4-ylpropoxy)pyrrolidin-1-yl]acetamide
   Show/Hide
 C29H37N9O3S  1
1
IC50 = 10.8 nM
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CP0268441
 Compound Info 
5-(2,5-Dihydroxy-benzylamino)-N-[2-(4-fluoro-phenyl)-ethyl]-2-hydroxy-benzamide
   Show/Hide
 C22H21FN2O4  1
1
GI50 = 9200 nM
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CP0269931
 Compound Info 
(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)-phenyl amine
   Show/Hide
 C18H17N3O2  1
1
IC50 < 100 nM
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CP0270683
 Compound Info 
5-(2,5-Dihydroxy-benzylamino)-2-hydroxy-N-(3-phenyl-propyl)-benzamide
   Show/Hide
 C23H24N2O4  1
1
GI50 = 24000 nM
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CP0278283
 Compound Info 
N-[[4-[3-(trifluoromethyl)phenyl]sulfonylphenyl]methyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
   Show/Hide
 C21H15F3N4O3S  1
1
IC50 = 8 nM
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CP0281834
 Compound Info 
N-[1-[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]indazol-6-yl]acetamide
   Show/Hide
 C19H16N8O  1
1
GI50 = 3700 nM
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CP0289423
 Compound Info 
N-(2-aminophenyl)-4-[5-(azetidin-1-ylmethyl)-3-chloropyridin-2-yl]benzamide
   Show/Hide
 C22H21ClN4O  1
1
IC50 = 302 nM
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CP0298941
 Compound Info 
2,4-Bisanilinopyrimidine, 5
   Show/Hide
 C23H17ClFN5O2  1
1
IC50 = 850 nM
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CP0299339
 Compound Info 
2-[(3S,4S)-3-hydroxy-4-(1,1,1-trifluoro-2-methylpropan-2-yl)oxypyrrolidin-1-yl]-N-[4-[4-[(5-methyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]sulfanylphenyl]acetamide
   Show/Hide
 C26H29F3N8O3S  1
1
IC50 = 9 nM
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CP0309054
 Compound Info 
N-hydroxy-6-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]hexanamide
   Show/Hide
 C15H18N6O2  1
1
IC50 = 8990 nM
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CP0319000
 Compound Info 
7-fluoro-3-(2-fluoro-4-iodoanilino)-N-[(2S)-2-hydroxypropoxy]furo[3,2-c]pyridine-2-carboxamide
   Show/Hide
 C17H14F2IN3O4  1
1
EC50 = 175 nM
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CP0334840
 Compound Info 
2-[(3R)-3-tert-butylsulfanylpyrrolidin-1-yl]-N-[4-[4-[(5-methyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]sulfanylphenyl]acetamide
   Show/Hide
 C26H32N8OS2  1
1
IC50 = 19.3 nM
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CP0336828
 Compound Info 
N-(2-aminophenyl)-4-[[6-(2-morpholin-4-ylethylamino)-1,3-benzothiazol-2-yl]sulfanylmethyl]benzamide
   Show/Hide
 C27H29N5O2S2  1
1
IC50 = 200 nM
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CP0341308
 Compound Info 
N-[1-(cyclohexylmethyl)piperidin-4-yl]-6-methoxy-7-(3-piperidin-1-ylpropoxy)-2-(4-propan-2-yl-1,4-diazepan-1-yl)quinazolin-4-amine
   Show/Hide
 C37H61N7O2  2
1
EC50 = 5800 nM
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2
EC50 = 6400 nM
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CP0345034
 Compound Info 
[(2R)-1-(4-tert-butylphenoxy)-3-(2-nitroimidazol-1-yl)propan-2-yl] 4-[(2-hydroxy-5-oxocyclopenta-1,3-dien-1-yl)methylideneamino]benzoate
   Show/Hide
 C29H28N4O7  1
1
GI50 = 16000 nM
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CP0349027
 Compound Info 
N-(2-aminophenyl)-4-{5-[(4-ethylpiperazin-1-yl)methyl]-3-fluoropyridin-2-yl}benzamide
   Show/Hide
 C25H28FN5O  1
1
IC50 = 436.52 nM
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CP0349028
 Compound Info 
N-(2-aminophenyl)-4-[5-(azetidin-1-ylmethyl)-3-cyanopyridin-2-yl]benzamide
   Show/Hide
 C23H21N5O  1
1
IC50 = 138.04 nM
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CP0350802
 Compound Info 
(4-benzylphenyl)-[1-(2,4-difluoro-5-hydroxybenzoyl)piperidin-4-yl]methanone
   Show/Hide
 C26H23F2NO3  1
1
IC50 = 5300 nM
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CP0358636
 Compound Info 
N-[2-(4-chlorophenyl)ethyl]-5-[(2,5-dihydroxyphenyl)methylamino]-2-hydroxybenzamide
   Show/Hide
 C22H21ClN2O4  1
1
GI50 = 15000 nM
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CP0370065
 Compound Info 
5-(4-chlorophenyl)-2-(4-methoxyphenyl)-[1,3]thiazolo[3,2-b][1,2,4]triazole
   Show/Hide
 C17H12ClN3OS  1
1
LC50 > 50000 nM
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CP0370695
 Compound Info 
4-[7-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]imidazo[1,2-a]pyridin-3-yl]-2-phenylmethoxybenzamide
   Show/Hide
 C28H28N6O2  1
1
IC50 = 1060 nM
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CP0371187
 Compound Info 
N-[2-amino-5-(1-methylpyrazol-4-yl)phenyl]-6-(2-oxo-1-oxa-3,8-diazaspiro[4.5]decan-8-yl)pyridine-3-carboxamide
   Show/Hide
 C23H25N7O3  1
1
GI50 = 2120 nM
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CP0373424
 Compound Info 
N-(2-amino-5-thiophen-2-ylphenyl)-6-(1-oxo-2,8-diazaspiro[4.5]decan-8-yl)pyridine-3-carboxamide
   Show/Hide
 C24H25N5O2S  1
1
GI50 = 190 nM
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CP0373425
 Compound Info 
N-(2-amino-5-thiophen-2-ylphenyl)-6-(2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl)pyridine-3-carboxamide
   Show/Hide
 C23H24N6O2S  1
1
GI50 = 320 nM
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CP0373929
 Compound Info 
N-(2-aminophenyl)-6-(2,8-diazaspiro[4.5]decan-8-yl)pyridine-3-carboxamide
   Show/Hide
 C20H25N5O  1
1
GI50 = 1340 nM
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CP0378540
 Compound Info 
7-tert-butylcarbonyloxy-4-hydroxybenzo[a]pyrrolo[3,4-c]carbazole-1,3(2H,8H)-dione
   Show/Hide
 C23H18N2O5  1
1
IC50 = 8760 nM
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CP0378573
 Compound Info 
N-benzyl-2-[2-[5-(dimethylamino)pentyl-methylamino]-3-(4-phenylphenyl)-4H-quinazolin-4-yl]acetamide
   Show/Hide
 C37H43N5O  1
1
IC50 = 5600 nM
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CP0379577
 Compound Info 
N-[3-[[(5S,5aS,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-5-yl]amino]phenyl]-N'-hydroxyheptanediamide
   Show/Hide
 C34H37N3O10  1
1
IC50 = 19620 nM
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CP0380847
 Compound Info 
CHEBI:66041
   Show/Hide
 C14H8N2O2  1
1
IC50 = 30000 nM
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CP0383276
 Compound Info 
N-(4-methoxyphenyl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
   Show/Hide
 C16H17N3O2  1
1
GI50 = 34 nM
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CP0385531
 Compound Info 
CHEBI:67291
   Show/Hide
 C28H38O5  1
1
IC50 = 24400 nM
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CP0385532
 Compound Info 
4-[[9-chloro-7-(2-fluorophenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]benzoic acid
   Show/Hide
 C25H16ClFN4O2  1
1
GI50 = 950 nM
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CP0386864
 Compound Info 
N-benzyl-2-[3-phenyl-2-(5-pyrrolidin-1-ylpentylsulfanyl)-4H-quinazolin-4-yl]acetamide
   Show/Hide
 C32H38N4OS  1
1
IC50 = 31300 nM
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CP0386865
 Compound Info 
2-[2-[5-(dimethylamino)pentylsulfanyl]-3-[4-(4-fluorophenyl)phenyl]-4H-quinazolin-4-yl]-N-[(4-fluorophenyl)methyl]acetamide
   Show/Hide
 C36H38F2N4OS  1
1
IC50 = 9300 nM
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CP0387131
 Compound Info 
N-[4-[2-[(2S,3S,5S)-2-[[tert-butyl(dimethyl)silyl]oxymethyl]-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl]-1,3-dithian-2-yl]phenyl]-N'-hydroxyhexanediamide
   Show/Hide
 C32H48N4O7S2Si  1
1
GI50 = 26300 nM
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CP0389087
 Compound Info 
N-[4-[[(5S,5aS,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-5-yl]amino]phenyl]-N'-hydroxyheptanediamide
   Show/Hide
 C34H37N3O10  1
1
IC50 = 2940 nM
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CP0391866
 Compound Info 
N-(2-aminophenyl)-6-[4-[2-[3-(1-methylpyrazol-4-yl)-6-oxopyridazin-1-yl]ethoxy]quinolin-7-yl]oxyhexanamide
   Show/Hide
 C31H33N7O4  1
1
IC50 = 7000 nM
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CP0393396
 Compound Info 
8-[[(19S)-10,19-diethyl-7-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-19-yl]oxy]-8-oxooctanoic acid
   Show/Hide
 C30H32N2O8  1
1
IC50 = 28.98 nM
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CP0394023
 Compound Info 
(E)-3-[4-[3-[(dimethylamino)methyl]-2-methylindol-1-yl]sulfonylphenyl]-N-hydroxyprop-2-enamide
   Show/Hide
 C21H23N3O4S  1
1
GI50 = 550 nM
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CP0394024
 Compound Info 
1-[3-[(E)-3-(hydroxyamino)-3-oxoprop-1-enyl]phenyl]sulfonyl-N,N-dimethylindole-3-carboxamide
   Show/Hide
 C20H19N3O5S  1
1
GI50 = 2490 nM
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CP0396807
 Compound Info 
[5-(2,4-dichloroanilino)-2,4-dihydroxyphenyl]-(1,3-dihydroisoindol-2-yl)methanone
   Show/Hide
 C21H16Cl2N2O3  1
1
GI50 = 10630 nM
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CP0397887
 Compound Info 
N-[4-(3-cyanoanilino)thieno[3,2-d]pyrimidin-6-yl]-N'-hydroxyoctanediamide
   Show/Hide
 C21H22N6O3S  1
1
IC50 = 2090 nM
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CP0404010
 Compound Info 
6-[3-[[(5S,5aS,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-5-yl]amino]phenoxy]-N-hydroxyhexanamide
   Show/Hide
 C33H36N2O10  1
1
IC50 = 5720 nM
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CP0404458
 Compound Info 
1-[3-[2-[(5,6-diphenylfuro[2,3-d]pyrimidin-4-yl)amino]ethyl]phenyl]-3-phenylurea
   Show/Hide
 C33H27N5O2  1
1
EC50 > 10000 nM
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CP0405350
 Compound Info 
N-[4-[2-[(2S,3S,5R)-2-[[tert-butyl(dimethyl)silyl]oxymethyl]-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl]-1,3-dithian-2-yl]phenyl]-N'-hydroxyhexanediamide
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 C32H48N4O7S2Si  1
1
GI50 = 26300 nM
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CP0406750
 Compound Info 
(E)-3-[3-[3-[(dimethylamino)methyl]-2-methylindol-1-yl]sulfonylphenyl]-N-hydroxyprop-2-enamide
   Show/Hide
 C21H23N3O4S  1
1
GI50 = 500 nM
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CP0406751
 Compound Info 
1-[4-[(E)-3-(hydroxyamino)-3-oxoprop-1-enyl]phenyl]sulfonyl-N,N-dimethylindole-3-carboxamide
   Show/Hide
 C20H19N3O5S  1
1
GI50 = 2140 nM
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CP0406752
 Compound Info 
1-[[4-[(E)-3-(hydroxyamino)-3-oxoprop-1-enyl]phenyl]methyl]-N,N-dimethylindole-3-carboxamide
   Show/Hide
 C21H21N3O3  1
1
GI50 = 750 nM
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CP0407311
 Compound Info 
1-cyano-2-[6-[cyclohexyl(2-morpholin-4-ylethoxy)sulfamoyl]hexyl]-3-pyridin-4-ylguanidine
   Show/Hide
 C25H41N7O4S  1
1
IC50 > 5000 nM
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CP0408582
 Compound Info 
1-[3-[4-[1-adamantyl(phenyl)methyl]phenyl]propyl]piperazine
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 C30H40N2  2
1
GI50 = 2.96 nM
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2
LC50 = 8.74 nM
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CP0409135
 Compound Info 
N-[4-(3-ethynylanilino)thieno[3,2-d]pyrimidin-6-yl]-N'-hydroxyoctanediamide
   Show/Hide
 C22H23N5O3S  1
1
IC50 = 1010 nM
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CP0410739
 Compound Info 
methyl (2E)-2-[2-[[3-[(4-chlorophenyl)methoxy]phenoxy]methyl]phenyl]-2-methoxyiminoacetate
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 C24H22ClNO5  1
1
IC50 = 1620 nM
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CP0412462
 Compound Info 
1-[3-[4-[1-adamantyl(phenyl)methyl]phenyl]propyl]-4-benzylpiperazine
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 C37H46N2  1
1
GI50 = 7.72 nM
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CP0412911
 Compound Info 
[(1R)-1-[[(2S)-2-[[(3E,5E)-3,5-bis[(4-fluorophenyl)methylidene]-4-oxopiperidine-1-carbonyl]amino]-3-phenylpropanoyl]amino]-3-methylbutyl]boronic acid
   Show/Hide
 C34H36BF2N3O5  1
1
IC50 = 203 nM
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CP0413073
 Compound Info 
(E)-3-[3-[3-[(dimethylamino)methyl]indol-1-yl]sulfonylphenyl]-N-hydroxyprop-2-enamide
   Show/Hide
 C20H21N3O4S  1
1
GI50 = 540 nM
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CP0415607
 Compound Info 
8-(2-phenyl-3H-benzimidazole-5-carbonyl)-2-[4-(trifluoromethyl)phenyl]-2,8-diazaspiro[4.5]decan-3-one
   Show/Hide
 C29H25F3N4O2  1
1
IC50 = 1220 nM
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CP0416995
 Compound Info 
N-[4-(2,4-difluoroanilino)thieno[3,2-d]pyrimidin-6-yl]-N'-hydroxyoctanediamide
   Show/Hide
 C20H21F2N5O3S  1
1
IC50 = 1940 nM
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CP0416999
 Compound Info 
N-[4-(4-chloro-2-fluoroanilino)thieno[3,2-d]pyrimidin-6-yl]-N'-hydroxyoctanediamide
   Show/Hide
 C20H21ClFN5O3S  1
1
IC50 = 1790 nM
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CP0421570
 Compound Info 
N-(5-methoxynaphthalen-2-yl)-N,2-dimethyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine
   Show/Hide
 C20H21N3O  1
1
GI50 < 10 nM
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CP0422774
 Compound Info 
6-(1-acetyl-1,8-diazaspiro[4.5]decan-8-yl)-N-(2-amino-5-(thiophen-2-yl)phenyl)nicotinamide
   Show/Hide
 C26H29N5O2S  1
1
GI50 = 470 nM
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CP0422780
 Compound Info 
N-(2-amino-5-thiophen-2-ylphenyl)-6-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)pyridine-3-carboxamide
   Show/Hide
 C29H28N6O2S  1
1
GI50 = 330 nM
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CP0423495
 Compound Info 
2-(3-hydroxyphenyl)-5-methyl-3-phenyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
   Show/Hide
 C19H15N3O2  1
1
IC50 = 75000 nM
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CP0423787
 Compound Info 
N-[(4-fluorophenyl)methyl]-2-[3-[4-(4-fluorophenyl)phenyl]-2-(5-pyrrolidin-1-ylpentylsulfanyl)-4H-quinazolin-4-yl]acetamide
   Show/Hide
 C38H40F2N4OS  1
1
IC50 = 7700 nM
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CP0424085
 Compound Info 
(2S)-N-hydroxy-4-methyl-2-[[1-[(3-phenylmethoxyphenyl)methyl]triazol-4-yl]methylcarbamoylamino]pentanamide
   Show/Hide
 C24H30N6O4  1
1
IC50 = 130100 nM
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CP0427170
 Compound Info 
3-[3-cyclopentylsulfanyl-5-[(4-fluorophenoxy)methyl]-1,2,4-triazol-4-yl]pyridine
   Show/Hide
 C19H19FN4OS  1
1
IC50 > 20000 nM
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CP0428395
 Compound Info 
(E)-N-hydroxy-3-[4-(4-hydroxyphenyl)cyclohexyl]prop-2-enamide
   Show/Hide
 C15H19NO3  1
1
IC50 = 370 nM
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CP0428526
 Compound Info 
N-[1-(2-bromo-4-methylanilino)isoquinolin-7-yl]-N'-hydroxyoctanediamide
   Show/Hide
 C24H27BrN4O3  1
1
IC50 = 260 nM
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CP0428528
 Compound Info 
N'-hydroxy-N-(1-morpholin-4-ylisoquinolin-7-yl)octanediamide
   Show/Hide
 C21H28N4O4  1
1
IC50 = 280 nM
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CP0430639
 Compound Info 
(E)-N-Hydroxy-3-{4-[3-(2-methyl-1H-indol-3-yl)pyrrolidin-1-ylmethyl]phenyl}acrylamide
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 C23H25N3O2  1
1
IC50 = 3.2 nM
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CP0431703
 Compound Info 
(2E,4E,8E)-9-(1,3-benzodioxol-5-yl)-N-hydroxynona-2,4,8-trienamide
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 C16H17NO4  1
1
IC50 = 4400 nM
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CP0434445
 Compound Info 
1-[(1-benzoylpiperidin-4-yl)methyl]-N-pyridin-3-ylbenzimidazole-5-carboxamide
   Show/Hide
 C26H25N5O2  1
1
IC50 > 1000 nM
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CP0434687
 Compound Info 
N-(2-amino-5-thiophen-2-ylphenyl)-6-spiro[1,2-dihydroindole-3,4'-piperidine]-1'-ylpyridine-3-carboxamide
   Show/Hide
 C28H27N5OS  1
1
GI50 = 2030 nM
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CP0434690
 Compound Info 
N-(2-amino-5-thiophen-2-ylphenyl)-6-[2-(2,2,2-trifluoroethyl)-2,8-diazaspiro[4.5]decan-8-yl]pyridine-3-carboxamide
   Show/Hide
 C26H28F3N5OS  1
1
GI50 = 740 nM
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CP0436569
 Compound Info 
N-(2-aminophenyl)-4-(1,3-thiazol-2-yl)benzamide
   Show/Hide
 C16H13N3OS  1
1
IC50 = 1819.7 nM
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CP0438690
 Compound Info 
(E)-N-Hydroxy-3-{4-[2-(2-methyl-1H-indol-3-ylmethyl)piperidin-1-ylmethyl]phenyl}acrylamide
   Show/Hide
 C25H29N3O2  1
1
IC50 = 27 nM
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CP0440224
 Compound Info 
N-[3-methoxy-6-[[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonylmethyl]pyridin-2-yl]methanesulfonamide
   Show/Hide
 C19H24N2O8S2  1
1
GI50 = 610 nM
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CP0443743
 Compound Info 
N-[1-[3-cyano-7-[(1-methylpyrazol-3-yl)amino]pyrazolo[1,5-a]pyrimidin-5-yl]indol-6-yl]acetamide
   Show/Hide
 C21H17N9O  1
1
GI50 = 460 nM
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CP0449938
 Compound Info 
1-[3-[4-[1-adamantyl(phenyl)methyl]phenyl]propyl]piperidine
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 C31H41N  1
1
GI50 = 3.37 nM
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CP0451722
 Compound Info 
(1S,7R,10S,16E,21R)-7-methyl-21-propan-2-yl-2-oxa-12,13-dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone
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 C20H30N4O6S2  1
1
GI50 = 10 nM
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CP0454504
 Compound Info 
N-[4-(2-fluoro-5-methylanilino)thieno[3,2-d]pyrimidin-6-yl]-N'-hydroxyoctanediamide
   Show/Hide
 C21H24FN5O3S  1
1
IC50 = 1330 nM
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CP0457329
 Compound Info 
4-[[3-[(dimethylamino)methyl]-2-methylindol-1-yl]methyl]-N-hydroxybenzamide
   Show/Hide
 C20H23N3O2  1
1
GI50 > 5000 nM
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CP0459320
 Compound Info 
7-(cyclopropylamino)-5-[6-(hydroxymethyl)indol-1-yl]pyrazolo[1,5-a]pyrimidine-3-carbonitrile
   Show/Hide
 C19H16N6O  1
1
GI50 = 10100 nM
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CP0459908
 Compound Info 
8-methoxy-N-phenyl-1,4-dihydroindeno[1,2-c]pyrazol-3-amine
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 C17H15N3O  1
1
IC50 = 570 nM
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CP0459921
 Compound Info 
N-(2-aminophenyl)-4-(1-benzylpiperidin-4-yl)benzamide
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 C25H27N3O  1
1
IC50 = 436.52 nM
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CP0461097
 Compound Info 
N-(2-amino-5-thiophen-3-ylphenyl)-6-(2-oxo-1-oxa-3,8-diazaspiro[4.5]decan-8-yl)pyridine-3-carboxamide
   Show/Hide
 C23H23N5O3S  1
1
GI50 = 270 nM
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CP0462589
 Compound Info 
6-(2-acetyl-2,7-diazaspiro[3.5]nonan-7-yl)-N-(2-amino-5-(thiophen-2-yl)phenyl)nicotinamide
   Show/Hide
 C25H27N5O2S  1
1
GI50 = 390 nM
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CP0463710
 Compound Info 
Chk1_82
   Show/Hide
 C17H15N3O  1
1
IC50 = 3100 nM
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CP0463830
 Compound Info 
N-(2-amino-5-thiophen-2-ylphenyl)-6-(3-oxo-2,8-diazaspiro[4.5]decan-8-yl)pyridine-3-carboxamide
   Show/Hide
 C24H25N5O2S  1
1
GI50 = 51 nM
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CP0463850
 Compound Info 
N-[2-amino-5-(1H-pyrazol-5-yl)phenyl]-6-(2,8-diazaspiro[4.5]decan-8-yl)pyridine-3-carboxamide
   Show/Hide
 C23H27N7O  1
1
GI50 > 20000 nM
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CP0463851
 Compound Info 
6-(2-acetyl-2,8-diazaspiro[4.5]decan-8-yl)-N-(2-amino-5-(thiophen-2-yl)phenyl)nicotinamide
   Show/Hide
 C26H29N5O2S  1
1
GI50 = 160 nM
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CP0463958
 Compound Info 
N-(2-aminophenyl)-4-[(2-methyl-4-oxoquinazolin-3-yl)methyl]benzamide
   Show/Hide
 C23H20N4O2  1
1
IC50 = 600 nM
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CP0466276
 Compound Info 
[(19S)-10,19-diethyl-7-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-19-yl] 2-[[8-(hydroxyamino)-8-oxooctanoyl]amino]acetate
   Show/Hide
 C32H36N4O9  1
1
IC50 = 30.47 nM
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CP0466410
 Compound Info 
4-[4-(difluoromethoxy)phenyl]-2-(2-methylindazol-5-yl)-6-(2,2,2-trifluoroethoxy)pyrido[3,2-c]pyridazin-3-one
   Show/Hide
 C24H16F5N5O3  1
1
IC50 < 100 nM
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CP0467700
 Compound Info 
N-(2-amino-5-thiophen-2-ylphenyl)-6-(4-hydroxy-8-azaspiro[4.5]decan-8-yl)pyridine-3-carboxamide
   Show/Hide
 C25H28N4O2S  1
1
GI50 = 280 nM
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CP0468041
 Compound Info 
(2S,3S,5S,7S,10S,16S,19S,22S,27R)-16-[(2S)-butan-2-yl]-7-tert-butyl-3-hydroxy-22-[(4-methoxyphenyl)methyl]-2,5,17,19,20-pentamethyl-8-oxa-29-thia-14,17,20,23,30-pentazatricyclo[25.2.1.010,14]triacont-1(30)-ene-9,15,18,21,24-pentone
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 C44H69N5O8S  1
1
IC50 = 0.69 nM
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CP0470133
 Compound Info 
(E)-N-Hydroxy-3-{4-[3-(1H-indol-3-yl)piperidin-1-ylmethyl]-phenyl}acrylamide
   Show/Hide
 C23H25N3O2  1
1
IC50 = 25 nM
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CP0471157
 Compound Info 
5-morpholin-4-ylsulfonyl-3-phenyldiazenyl-1H-indol-2-ol
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 C18H18N4O4S  1
1
IC50 = 10490 nM
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CP0472473
 Compound Info 
1-tert-butyl-3-(1H-indol-3-yl)pyrazolo[3,4-d]pyrimidin-4-amine
   Show/Hide
 C17H18N6  1
1
IC50 = 2500 nM
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CP0475008
 Compound Info 
N-[(3,4-dimethoxyphenyl)methyl]-4-[(4S)-4-(2-methylpropyl)-2,5-dioxoimidazolidin-1-yl]benzenesulfonamide
   Show/Hide
 C22H27N3O6S  1
1
IC50 = 4280 nM
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CP0476635
 Compound Info 
(E)-N-hydroxy-3-[4-[3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propylamino]phenyl]prop-2-enamide
   Show/Hide
 C21H21N7O2  1
1
IC50 = 25300 nM
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CP0481109
 Compound Info 
2-methoxy-5-[[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonylmethyl]pyridin-3-amine
   Show/Hide
 C18H22N2O6S  1
1
GI50 = 5 nM
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CP0482676
 Compound Info 
Apratoxin S4
   Show/Hide
 C44H69N5O8S  1
1
IC50 = 1.43 nM
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CP0485794
 Compound Info 
N-(2-aminophenyl)-4-[(3-oxo-1H-isoindol-2-yl)methyl]benzamide
   Show/Hide
 C22H19N3O2  1
1
IC50 = 500 nM
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CP0487793
 Compound Info 
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amine
   Show/Hide
 C19H17N3O3  1
1
IC50 = 5900 nM
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CP0488922
 Compound Info 
3-[3-[(4-bromophenoxy)methyl]-5-cyclopentylsulfanyl-1,2,4-triazol-4-yl]pyridine
   Show/Hide
 C19H19BrN4OS  1
1
IC50 = 18090 nM
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CP0490269
 Compound Info 
3-[3-cyclopentylsulfanyl-5-[(4-phenylphenoxy)methyl]-1,2,4-triazol-4-yl]pyridine
   Show/Hide
 C25H24N4OS  1
1
IC50 > 10000 nM
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CP0491269
 Compound Info 
(E)-3-{3-Fluoro-4-[3-(1H-indol-3-yl)piperidin-1-ylmethyl]-phenyl}-N-hydroxyacrylamide
   Show/Hide
 C23H24FN3O2  1
1
IC50 = 332 nM
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CP0492215
 Compound Info 
N-benzyl-4-[(2,5-dihydroxyphenyl)methylamino]benzamide
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 C21H20N2O3  1
1
GI50 = 10000 nM
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CP0492675
 Compound Info 
8-(7-methyl-1H-indazole-5-carbonyl)-2-[4-(trifluoromethyl)phenyl]-2,8-diazaspiro[4.5]decan-3-one
   Show/Hide
 C24H23F3N4O2  1
1
IC50 = 8670 nM
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CP0492676
 Compound Info 
8-(2-pyridin-4-yl-3H-benzimidazole-5-carbonyl)-2-[4-(trifluoromethyl)phenyl]-2,8-diazaspiro[4.5]decan-3-one
   Show/Hide
 C28H24F3N5O2  1
1
IC50 = 7640 nM
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CP0493853
 Compound Info 
4-[4-[(5-cyclopentylsulfanyl-4-pyridin-3-yl-1,2,4-triazol-3-yl)methoxy]-2-methylphenyl]benzenesulfonamide
   Show/Hide
 C26H27N5O3S2  1
1
IC50 = 1820 nM
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CP0495782
 Compound Info 
3-(cyclohexen-1-yl)-6-(4-methoxyphenyl)-2-phenyl-5-(1H-pyrazol-5-ylamino)-1H-pyrazolo[1,5-a]pyrimidin-7-one
   Show/Hide
 C28H26N6O2  1
1
IC50 = 80 nM
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CP0497544
 Compound Info 
4-((1-(4-methoxybenzyl)-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)-N-(2-aminophenyl)benzamide
   Show/Hide
 C30H26N4O4  1
1
IC50 = 800 nM
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CP0497546
 Compound Info 
N-(2-aminophenyl)-4-[(1-ethyl-2,4-dioxoquinazolin-3-yl)methyl]benzamide
   Show/Hide
 C24H22N4O3  1
1
IC50 = 400 nM
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CP0499106
 Compound Info 
(2E,4E)-5-(1,3-benzodioxol-5-yl)-N-hydroxypenta-2,4-dienamide
   Show/Hide
 C12H11NO4  1
1
IC50 = 9100 nM
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CP0502262
 Compound Info 
N-(2-amino-5-thiophen-2-ylphenyl)-6-(3-oxo-2,7-diazaspiro[3.5]nonan-7-yl)pyridine-3-carboxamide
   Show/Hide
 C23H23N5O2S  1
1
GI50 = 49 nM
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CP0505409
 Compound Info 
N-(2-aminophenyl)-4-[[1-[2-(dimethylamino)ethyl]-2,4-dioxoquinazolin-3-yl]methyl]benzamide
   Show/Hide
 C26H27N5O3  1
1
IC50 = 1000 nM
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CP0510789
 Compound Info 
N-hydroxy-11-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]undecanamide
   Show/Hide
 C20H28N6O2  1
1
IC50 = 41100 nM
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CP0510830
 Compound Info 
N-(2-aminophenyl)-4-[[1-(2-morpholin-4-ylethyl)-2,4-dioxoquinazolin-3-yl]methyl]benzamide
   Show/Hide
 C28H29N5O4  1
1
IC50 = 1000 nM
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CP0510831
 Compound Info 
N-(2-aminophenyl)-4-[(1,3-dioxoisoindol-2-yl)methyl]benzamide
   Show/Hide
 C22H17N3O3  1
1
IC50 = 5000 nM
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CP0510885
 Compound Info 
3-[3-cyclopentylsulfanyl-5-(phenoxymethyl)-1,2,4-triazol-4-yl]pyridine
   Show/Hide
 C19H20N4OS  1
1
IC50 > 20000 nM
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CP0513258
 Compound Info 
4-[7-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]imidazo[1,2-a]pyridin-3-yl]-2-[[3-(trifluoromethyl)phenyl]methoxy]benzamide
   Show/Hide
 C29H27F3N6O2  1
1
IC50 = 1290 nM
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CP0515171
 Compound Info 
N-(2-aminophenyl)-4-[(1-ethyl-2,4-dioxothieno[3,2-d]pyrimidin-3-yl)methyl]benzamide
   Show/Hide
 C22H20N4O3S  1
1
IC50 = 800 nM
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CP0515172
 Compound Info 
N-(2-aminophenyl)-4-[(4-oxoquinazolin-3-yl)methyl]benzamide
   Show/Hide
 C22H18N4O2  1
1
IC50 = 400 nM
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CP0517261
 Compound Info 
1-cyano-2-[6-[cyclohexylmethoxy(2-fluoroethyl)sulfamoyl]hexyl]-3-pyridin-4-ylguanidine
   Show/Hide
 C22H35FN6O3S  1
1
IC50 = 3.6 nM
   TI
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CP0517983
 Compound Info 
N-[4-[2-[(2S,3S,5S)-2-[[tert-butyl(dimethyl)silyl]oxymethyl]-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl]-1,3-dithian-2-yl]phenyl]-N'-hydroxyoctanediamide
   Show/Hide
 C34H52N4O7S2Si  2
1
GI50 = 4168.69 nM
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2
GI50 = 4170 nM
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CP0519137
 Compound Info 
5-morpholin-4-ylsulfonyl-3-[4-[(5-morpholin-4-ylsulfonyl-2-oxo-1H-indol-3-ylidene)amino]phenyl]imino-1H-indol-2-one
   Show/Hide
 C30H28N6O8S2  1
1
IC50 = 7480 nM
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CP0520959
 Compound Info 
(E)-N-hydroxy-3-[6-(4-nitrophenoxy)quinolin-2-yl]prop-2-enamide
   Show/Hide
 C18H13N3O5  1
1
GI50 = 1000 nM
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CP0522085
 Compound Info 
(E)-N-Hydroxy-3-{4-[3-(2-methyl-1H-indol-3-yl)piperidin-1-ylmethyl]-phenyl}acrylamide
   Show/Hide
 C24H27N3O2  1
1
IC50 = 5.6 nM
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CP0522086
 Compound Info 
(E)-3-{4-[(S)-3-(2-tert-Butyl-1H-indol-3-yl)piperidin-1-ylmethyl]-3-fluorophenyl}-N-hydroxyacrylamide
   Show/Hide
 C27H32FN3O2  1
1
IC50 = 143 nM
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CP0522235
 Compound Info 
N-(2-aminophenyl)-4-[(4-oxothieno[3,2-d]pyrimidin-3-yl)methyl]benzamide
   Show/Hide
 C20H16N4O2S  1
1
IC50 = 700 nM
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CP0522942
 Compound Info 
N-(2-aminophenyl)-4-(1-methylpiperidin-4-yl)benzamide
   Show/Hide
 C19H23N3O  1
1
IC50 = 831.76 nM
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CP0527664
 Compound Info 
N-[6-(4-chlorophenyl)-1H-indazol-3-yl]-N'-hydroxyoctanediamide
   Show/Hide
 C21H23ClN4O3  1
1
IC50 = 3900 nM
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CP0528775
 Compound Info 
1-[4-[4-[(5-cyclopentylsulfanyl-4-pyridin-3-yl-1,2,4-triazol-3-yl)methoxy]phenyl]phenyl]-2-hydroxyethanone
   Show/Hide
 C27H26N4O3S  1
1
IC50 = 1740 nM
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CP0529728
 Compound Info 
4-hydroxy-11-methyl-7-hydroxysulfonyloxybenzo[a]pyrrolo-[3,4-c]carbazole-1,3(2H,8H)-dione
   Show/Hide
 C19H12N2O7S  1
1
IC50 > 40000 nM
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CP0531200
 Compound Info 
N-[6-(3,5-dimethoxyphenyl)-1H-indazol-3-yl]-N'-hydroxyoctanediamide
   Show/Hide
 C23H28N4O5  1
1
IC50 = 9500 nM
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CP0531238
 Compound Info 
4-[[1-[[4-(diethylaminomethyl)phenyl]methyl]-2-oxo-4-pyridin-3-ylquinolin-3-yl]oxymethyl]-N-hydroxybenzamide
   Show/Hide
 C34H34N4O4  1
1
IC50 = 8400 nM
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CP0531960
 Compound Info 
N-[6-(2-fluorophenyl)-1H-indazol-3-yl]-N'-hydroxyoctanediamide
   Show/Hide
 C21H23FN4O3  1
1
IC50 = 4100 nM
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CP0532348
 Compound Info 
(E)-N-Hydroxy-3-{4-[3-(2-phenyl-1H-indol-3-yl)piperidin-1-ylmethyl]phenyl}acrylamide
   Show/Hide
 C29H29N3O2  1
1
IC50 = 6.9 nM
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CP0533058
 Compound Info 
(E)-3-{3-Fluoro-4-[3-(2-phenyl-1H-indol-3-yl)piperidin-1-ylmethyl]phenyl}-N-hydroxyacrylamide
   Show/Hide
 C29H28FN3O2  1
1
IC50 = 11 nM
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CP0533365
 Compound Info 
(E)-N-hydroxy-3-[2-[2-(2-methyl-1H-indol-3-yl)ethyl]-3,4-dihydro-1H-isoquinolin-6-yl]prop-2-enamide
   Show/Hide
 C23H25N3O2  1
1
IC50 = 119 nM
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CP0533473
 Compound Info 
N-[(2-hydroxy-5-morpholin-4-ylsulfonyl-1H-indol-3-yl)imino]-2-iminochromene-3-carboxamide
   Show/Hide
 C22H19N5O6S  1
1
IC50 = 6750 nM
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CP0534804
 Compound Info 
(E)-1-[1-(4-chlorophenyl)-5-methyltriazol-4-yl]-3-(3,4-dimethoxyphenyl)prop-2-en-1-one
   Show/Hide
 C20H18ClN3O3  1
1
IC50 = 260 nM
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CP0535585
 Compound Info 
9-[6-[5-[(2,4-difluorophenyl)sulfonylamino]-6-methoxypyridin-3-yl]-4-methylquinazolin-8-yl]oxy-N-hydroxynonanamide
   Show/Hide
 C30H33F2N5O6S  1
1
IC50 = 4000 nM
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CP0546115
 Compound Info 
N'-hydroxy-N-(6-thiophen-3-yl-1H-indazol-3-yl)octanediamide
   Show/Hide
 C19H22N4O3S  1
1
IC50 = 7500 nM
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CP0548783
 Compound Info 
(E)-N-hydroxy-3-[4-[(2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)methyl]phenyl]prop-2-enamide
   Show/Hide
 C22H23N3O2  1
1
GI50 = 730 nM
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CP0551675
 Compound Info 
2-(dimethylamino)ethyl 4-[4-[[5-chloro-4-[2-(methylcarbamoyl)anilino]pyrimidin-2-yl]amino]benzoyl]piperazine-1-carbodithioate
   Show/Hide
 C28H33ClN8O2S2  1
1
IC50 = 4 nM
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CP0552272
 Compound Info 
N-(2-aminophenyl)-4-[(4-oxo-2,3-dihydrochromen-3-yl)methyl]benzamide
   Show/Hide
 C23H20N2O3  1
1
IC50 = 900 nM
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CP0553866
 Compound Info 
3-(4-methoxyphenyl)-9-morpholin-4-ylsulfonyl-1-oxo-6,11a-dihydroindolo[3,2-b]quinoxaline-2,4-dicarbonitrile
   Show/Hide
 C27H20N6O5S  1
1
IC50 = 9730 nM
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CP0556615
 Compound Info 
4-[4-(difluoromethoxy)phenyl]-2-(2-methylindazol-5-yl)-6-(3,3,3-trifluoropropoxy)pyrido[3,2-c]pyridazin-3-one
   Show/Hide
 C25H18F5N5O3  1
1
IC50 >= 100 nM
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CP0557086
 Compound Info 
(1S,7S,10S,16E,21R)-7-benzyl-21-propan-2-yl-2-oxa-12,13-dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone
   Show/Hide
 C26H34N4O6S2  1
1
GI50 = 250 nM
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CP0558284
 Compound Info 
(1S,7R,10S,16E,21R)-7-(2-methylpropyl)-21-propan-2-yl-2-oxa-12,13-dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone
   Show/Hide
 C23H36N4O6S2  1
1
GI50 = 22 nM
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CP0565042
 Compound Info 
(1S,7S,10S,16E,21R)-7-methyl-21-propan-2-yl-2-oxa-12,13-dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone
   Show/Hide
 C20H30N4O6S2  1
1
GI50 = 11000 nM
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CP0565997
 Compound Info 
N'-hydroxy-N-[6-(3-methoxyphenyl)-1H-indazol-3-yl]octanediamide
   Show/Hide
 C22H26N4O4  1
1
IC50 = 8100 nM
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CP0566736
 Compound Info 
N-[4-[2-[(2S,3S,5S)-2-[[tert-butyl(dimethyl)silyl]oxymethyl]-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl]-1,3-dithian-2-yl]phenyl]-N'-hydroxyheptanediamide
   Show/Hide
 C33H50N4O7S2Si  1
1
GI50 = 14800 nM
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CP0566922
 Compound Info 
N-(1,3-benzodioxol-5-yl)-1,4-dihydroindeno[1,2-c]pyrazol-3-amine
   Show/Hide
 C17H13N3O2  1
1
IC50 = 6900 nM
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CP0568372
 Compound Info 
6-(2,2-difluoroethoxy)-4-[4-(difluoromethoxy)phenyl]-2-(2-methylindazol-5-yl)pyrido[3,2-c]pyridazin-3-one
   Show/Hide
 C24H17F4N5O3  1
1
IC50 < 100 nM
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CP0569312
 Compound Info 
6-ethoxy-4-(4-methoxyphenyl)-2-(2-methylindazol-5-yl)pyrido[3,2-c]pyridazin-3-one
   Show/Hide
 C24H21N5O3  1
1
IC50 < 100 nM
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CP0573437
 Compound Info 
2-[(4-fluorophenyl)methyl-[[4-(hydroxycarbamoyl)phenyl]methyl]amino]-N-(3-imidazol-1-ylpropyl)-1,3-thiazole-5-carboxamide
   Show/Hide
 C25H25FN6O3S  1
1
IC50 = 99000 nM
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CP0576207
 Compound Info 
2-(dimethylamino)ethyl 4-[4-[[5-methyl-4-[2-(methylcarbamoyl)anilino]pyrimidin-2-yl]amino]benzoyl]piperazine-1-carbodithioate
   Show/Hide
 C29H36N8O2S2  1
1
IC50 = 10 nM
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CP0633457
 Compound Info 
6-bromo-4-((4-(piperidin-1-ylmethyl)phenylamino)methylene)isoquinoline-1,3(2H,4H)-dione
   Show/Hide
 C22H22BrN3O2  1
1
IC50 = 5000 nM
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CP0633459
 Compound Info 
(4Z)-4-({[4-(4-Methylpiperazin-1-yl)phenyl]amino}methylene)-6-(1H-pyrrol-1-yl)isoquinoline-1,3(2H,4H)-dione
   Show/Hide
 C25H25N5O2  1
1
IC50 = 1500 nM
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CP0633461
 Compound Info 
(4Z)-6-Bromo-4-({[4-(4-methylpiperazin-1-yl)phenyl]amino}-methylene)isoquinoline-1,3(2H,4H)-dione
   Show/Hide
 C21H21BrN4O2  1
1
IC50 = 3100 nM
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CP0633607
 Compound Info 
(4Z)-6-Iodo-4-[({4-[(2S,5R)-2,4,5-trimethylpiperazin-1-yl]phenyl}amino)methylene]-isoquinoline-1,3(2H,4H)-dione
   Show/Hide
 C23H25IN4O2  1
1
IC50 = 5000 nM
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CP0633612
 Compound Info 
(4Z)-6-Iodo-4-({[4-(piperidin-1-ylmethyl)phenyl]amino}methylene)isoquinoline-1,3(2H,4H)-dione
   Show/Hide
 C22H22IN3O2  1
1
IC50 = 2700 nM
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CP0634523
 Compound Info 
(4Z)-4-({[4 Piperidin-1-ylmethyl]phenyl}amino)methylene)}-6-(1H-pyrrol-1-yl)isoquinoline-1,3(2H,4H)-dione
   Show/Hide
 C26H26N4O2  1
1
IC50 = 2700 nM
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CP0635234
 Compound Info 
(4Z)-4-({[3-Fluoro-4-(4-methylpiperazin-1-yl)phenyl]amino}-methylene)-6-(3-furyl)isoquinoline-1,3(2H,4H)-dione
   Show/Hide
 C25H23FN4O3  1
1
IC50 = 2200 nM
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CP0635237
 Compound Info 
(4Z)-6-(3-Furyl)-4-({[6-(4-methylpiperazin-1-yl)pyridazin-3-yl]amino}methylene)isoquinoline-1,3(2H,4H)-dione
   Show/Hide
 C23H22N6O3  1
1
IC50 = 1900 nM
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CP0635807
 Compound Info 
(4Z)-6-Iodo-4-[({4-[(3R,5S)-3,4,5-trimethylpiperazin-1-yl]phenyl}amino)methylene]-isoquinoline-1,3(2H,4H)-dione
   Show/Hide
 C23H25IN4O2  1
1
IC50 = 2100 nM
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CP0635812
 Compound Info 
6-(furan-3-yl)-4-((4-(piperidin-1-ylmethyl)phenylamino)methylene)isoquinoline-1,3(2H,4H)-dione
   Show/Hide
 C26H25N3O3  1
1
IC50 = 1900 nM
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CP0637006
 Compound Info 
(4Z)-6-(3-Furyl)-4-({[5-(4-methylpiperazin-1-yl)pyridin-2-yl]amino}methylene)isoquinoline-1,3(2H,4H)-dione
   Show/Hide
 C24H23N5O3  1
1
IC50 = 760 nM
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CP0637016
 Compound Info 
(4Z)-4-({[4-(4-Methylpiperazin-1-yl)phenyl]amino}methylene)-6-phenylisoquinoline-1,3(2H,4H)-dione
   Show/Hide
 C27H26N4O2  1
1
IC50 = 2800 nM
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CP0637513
 Compound Info 
(4Z)-6-(3-Furyl)-4-({[2-(4-methylpiperazin-1-yl)pyrimidin-5-yl]amino}methylene)isoquinoline-1,3(2H,4H)-dione
   Show/Hide
 C23H22N6O3  1
1
IC50 = 1100 nM
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CP0639837
 Compound Info 
8-[2-methoxy-5-(4-methylpiperazin-1-yl)anilino]-1-methyl-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamide
   Show/Hide
 C23H28N8O2  1
1
IC50 = 25 nM
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CP0641259
 Compound Info 
11-hydroxybenzo[a]pyrrolo[3,4-c]carbazole-1,3,4,7(2H,8H)-tetraone
   Show/Hide
 C18H8N2O5  1
1
IC50 = 15400 nM
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CP0659902
 Compound Info 
7-(5-{4-[(10-Hydroxy-14-methyl-5-oxo-5,7,8,13,13b,14-hexahydro-indolo[2',3':3,4]pyrido[2,1-b]quinazolin-3-ylamino)-methyl]-phenyl}-[1,3,4]oxadiazol-2-yl)-heptanoic acid hydroxyamide
   Show/Hide
 C35H37N7O5  1
1
IC50 = 9700 nM
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CP0659903
 Compound Info 
Pentanedioic acid hydroxyamide (10-hydroxy-14-methyl-5-oxo-5,7,8,13,13b,14-hexahydro-indolo[2',3':3,4]pyrido[2,1-b]quinazolin-3-yl)-amide
   Show/Hide
 C24H25N5O5  1
1
IC50 = 31000 nM
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CP0664321
 Compound Info 
Heptanedioic acid hydroxyamide (10-hydroxy-14-methyl-5-oxo-5,7,8,13,13b,14-hexahydro-indolo[2',3':3,4]pyrido[2,1-b]quinazolin-3-yl)-amide
   Show/Hide
 C26H29N5O5  1
1
IC50 = 35000 nM
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CP0664425
 Compound Info 
1-(2-fluoro-4-methyl-5-(2-methyl-7-(methylamino)-1,6-naphthyridin-3-yl)phenyl)-3-((S)-2-hydroxy-3,3-dimethylbutyl)urea
   Show/Hide
 C24H30FN5O2  1
1
IC50 = 174 nM
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CP0668312
 Compound Info 
3-(1'-(4-fluorobenzyl)-4-oxospiro[chroman-2,4'-piperidine]-6-yl)-N-hydroxyacrylamide
   Show/Hide
 C23H23FN2O4  1
1
IC50 = 777 nM
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CP0677468
 Compound Info 
1-(3,3-dimethylbutyl)-3-(5-(1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluoro-4-methylphenyl)urea
   Show/Hide
 C25H32FN5O2  1
1
IC50 = 130 nM
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CP0684598
 Compound Info 
benzo[a]pyrrolo[3,4-c]carbazole-1,3,4,7(2H,8H)-tetraone
   Show/Hide
 C18H8N2O4  1
1
IC50 = 5300 nM
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CP0689759
 Compound Info 
5-(5-{4-[(10-Hydroxy-14-methyl-5-oxo-5,7,8,13,13b,14-hexahydro-indolo[2',3':3,4]pyrido[2,1-b]quinazolin-3-ylamino)-methyl]-phenyl}-[1,3,4]oxadiazol-2-yl)-pentanoic acid hydroxyamide
   Show/Hide
 C33H33N7O5  1
1
IC50 = 4900 nM
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CP0713838
 Compound Info 
E/Z-(S,E)-2-(3-tert-butoxy-4-(hydroxyimino)pyrrolidin-1-yl)-N-(4-(4-(5-methyl-1H-pyrazol-3-ylamino)pyrrolo[1,2-f][1,2,4]triazin-2-ylthio)phenyl)acetamide
   Show/Hide
 C26H31N9O3S  1
1
IC50 = 8 nM
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CP0722470
 Compound Info 
1-(3,3-Dimethylbutyl)-3-(2-fluoro-5-(7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl)phenyl)urea
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 C22H27FN6O  1
1
IC50 = 280 nM
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CP0724068
 Compound Info 
1-(3,3-dimethylbutyl)-3-(2-fluoro-4-methyl-5-(2-methyl-7-(methylamino)-1,6-naphthyridin-3-yl)phenyl)urea
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 C24H30FN5O  1
1
IC50 = 320 nM
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CP0798748
 Compound Info 
Octanedioic acid hydroxyamide {4-[(10-hydroxy-14-methyl-5-oxo-5,7,8,13,13b,14-hexahydro-indolo[2',3':3,4]pyrido[2,1-b]quinazolin-3-ylamino)-methyl]-phenyl}-amide
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 C34H38N6O5  1
1
IC50 = 2100 nM
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CP0868127
 Compound Info 
2-(5-(4-Chlorophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
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 C18H14ClN3OS  1
1
IC50 = 1700 nM
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CP0876829
 Compound Info 
1,1'-(tetradecane-1,14-diyl)bis(4-(dimethylamino)pyridinium)bromide
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 C28H48Br2N4  1
1
GI50 = 290 nM
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CP0903919
 Compound Info 
N-[5-[[3-cyano-7-(cyclobutylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-4-fluoro-2-methylphenyl]acetamide
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 C20H20FN7O  1
1
GI50 = 410 nM
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CP0908798
 Compound Info 
N-[5-[[3-cyano-7-[[1-(2-pyrrolidin-1-ylethyl)pyrazol-3-yl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-methyl-phenyl]acetamide
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 C25H28N10O  1
1
GI50 = 100 nM
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CP0909285
 Compound Info 
N-(5-(3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-ylamino)-2-cyclopropyl-4-fluorophenyl)acetamide
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 C21H20FN7O  1
1
GI50 = 12 nM
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CP0911841
 Compound Info 
5-Chloro-N-[(N-benzyl)4-sulfamoylbenzyl]salicylamide
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 C21H19ClN2O4S  1
1
GI50 = 5900 nM
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CP0926275
 Compound Info 
3-(2-Ethoxyquinolin-6-yl)-1-((1-methylpiperidin-4-yl)-methyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
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 C23H27N7O  1
1
IC50 > 55200 nM
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CP0930355
 Compound Info 
5-(3-Hydroxy-4-oxo-1,4-dihydroquinolin-2-yl)-2-(piperidin-1-yl)-benzamide
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 C21H21N3O3  1
1
IC50 = 4460 nM
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CP0935434
 Compound Info 
N-[5-[[3-cyano-7-[[1-(2-morpholinoethyl)imidazol-4-yl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-methyl-phenyl]acetamide
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 C25H28N10O2  1
1
GI50 = 670 nM
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CP0944518
 Compound Info 
Octanedioic acid hydroxyamide (10-hydroxy-14-methyl-5-oxo-5,7,8,13,13b,14-hexahydro-indolo[2',3':3,4]pyrido[2,1-b]quinazolin-3-yl)-amide
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 C27H31N5O5  1
1
IC50 = 20000 nM
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CP0961810
 Compound Info 
(E)-3-(3-chlorophenyl)-N-(2-((1,1-dioxidotetrahydro-2H-thiopyran-4-yl)(methyl)amino)-2-oxoethyl)acrylamide
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 C17H21ClN2O4S  1
1
IC50 = 561.4 nM
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Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Colon)
Cell Line Name Organism Disease
HT-29
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
SW480
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
Caco-2
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
HCA7
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
LS174T
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
LS180
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
SW1116
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
WiDr
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
S1-M1-80
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
SW48
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
S1
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
Caco-2/TC-7
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
COLO 320DM
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
COLO 320
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
RKO
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
KM12-Luc
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
TC71
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
KM12
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
KM12-L4A
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
HCA2
 Cell Line Info 
Homo sapiens (Human) Rectosigmoid adenocarcinoma
CT26
 Cell Line Info 
Mus musculus (Mouse) Mouse colon adenocarcinoma
51B LiM-1
 Cell Line Info 
Mus musculus (Mouse) Mouse colon adenocarcinoma
GLUTag
 Cell Line Info 
Mus musculus (Mouse) Neuroendocrine cell carcinoma of the mouse intestinal tract
CC531
 Cell Line Info 
Rattus norvegicus (Rat) Adenocarcinoma of the rat colon