| Compound ID |
Compound Name |
Compound Formula |
|
CP0261967
|
(1R,9S,12R)-13-[8-[[1-(2-fluoro-2-methylpropyl)piperidin-4-yl]amino]-3-methyl-[1,2,4]triazolo[4,3-b]pyridazine-6-carbonyl]-12-propan-2-yl-11,13-diazatricyclo[7.3.1.02,7]trideca-2,4,6-trien-10-one
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|
C30H39FN8O2
|
4
|
| 1 |
IC50 = 50.12 nM
|
|
|
| 2 |
IC50 = 79.43 nM
|
|
|
| 3 |
IC50 = 100 nM
|
|
|
| 4 |
IC50 = 125.89 nM
|
|
|
|
CP0533312
|
8-[[(3R,4R,5S)-3-[(4,4-difluorocyclohexyl)methoxy]-5-methoxypiperidin-4-yl]amino]-3-methyl-5-(5-methylpyridin-3-yl)-1H-1,7-naphthyridin-2-one
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|
C28H35F2N5O3
|
4
|
| 1 |
IC50 = 158.49 nM
|
|
|
| 2 |
IC50 = 199.53 nM
|
|
|
| 3 |
IC50 = 251.19 nM
|
|
|
| 4 |
IC50 = 630.96 nM
|
|
|
|
CP0941506
|
2-Methyl-4((1R,2R,5S)-2-methyl-4-oxo-1,2,3,4,5,6-hexahydro-1,5-epiminobenzo[d]azocine-11-carbonyl)-6-(trifluoromethoxy)-2,9-dihydro-1H-pyrido[3,4-b]indol-1-one
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|
C26H21F3N4O4
|
3
|
| 1 |
IC50 = 501.19 nM
|
|
|
| 2 |
IC50 = 794.33 nM
|
|
|
| 3 |
IC50 = 1258.93 nM
|
|
|
|
CP0537714
|
(1R,9S,12R)-13-[8-[[1-(2,2-difluoropropyl)piperidin-4-yl]amino]-3-methyl-[1,2,4]triazolo[4,3-b]pyridazine-6-carbonyl]-12-propan-2-yl-11,13-diazatricyclo[7.3.1.02,7]trideca-2,4,6-trien-10-one
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|
C29H36F2N8O2
|
1
|
| 1 |
IC50 = 501.19 nM
|
|
|
|
CP0575351
|
(1R,9S,12R)-13-[8-[3-(4,4-difluoropiperidin-1-yl)propylamino]-3-methyl-[1,2,4]triazolo[4,3-b]pyridazine-6-carbonyl]-12-propan-2-yl-11,13-diazatricyclo[7.3.1.02,7]trideca-2,4,6-trien-10-one
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|
C29H36F2N8O2
|
1
|
| 1 |
IC50 = 1258.93 nM
|
|
|
|
CP0571907
|
(1R,9S,12R)-13-[3-methyl-8-(3-pyrrolidin-1-ylpropylamino)-[1,2,4]triazolo[4,3-b]pyridazine-6-carbonyl]-12-propan-2-yl-11,13-diazatricyclo[7.3.1.02,7]trideca-2,4,6-trien-10-one
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|
C28H36N8O2
|
1
|
| 1 |
IC50 = 1995.26 nM
|
|
|
|
CP0489411
|
(1R,9S)-13-[3-methyl-8-[(1-methylpiperidin-4-yl)amino]-[1,2,4]triazolo[4,3-b]pyridazine-6-carbonyl]-11,13-diazatricyclo[7.3.1.02,7]trideca-2,4,6-trien-10-one
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|
C24H28N8O2
|
1
|
| 1 |
IC50 = 2511.89 nM
|
|
|
