| Compound ID |
Compound Name |
Compound Formula |
|
CP0698141
|
1-(3,3-Dimethylbutyl)-3-[2-fluoro-4-methyl-5-(2-methylaminopyrido[2,3-d]pyrimidin-6-yl)phenyl]urea
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|
C22H27FN6O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0683654
|
1-(3,3-Dimethylbutyl)-3-(2-fluoro-5-(2-methyl-7-(methylamino)-1,6-naphthyridin-3-yl)phenyl)urea
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|
C23H28FN5O
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0722470
|
1-(3,3-Dimethylbutyl)-3-(2-fluoro-5-(7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl)phenyl)urea
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|
C22H27FN6O
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0684485
|
(S)-1-(3-tert-butylisoxazol-5-yl)-3-(2-fluoro-5-(7-(methylamino)-2-oxo-1-(tetrahydrofuran-3-yl)-1,2-dihydro-1,6-naphthyridin-3-yl)phenyl)urea
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|
C27H29FN6O4
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
|
CP0683304
|
1-(3-tert-butylisoxazol-5-yl)-3-(5-(1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluorophenyl)urea
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|
C25H27FN6O3
|
1
|
| 1 |
IC50 = 91 nM
|
|
|
|
CP0677468
|
1-(3,3-dimethylbutyl)-3-(5-(1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluoro-4-methylphenyl)urea
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|
C25H32FN5O2
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0724068
|
1-(3,3-dimethylbutyl)-3-(2-fluoro-4-methyl-5-(2-methyl-7-(methylamino)-1,6-naphthyridin-3-yl)phenyl)urea
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|
C24H30FN5O
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0672877
|
1-(3,3-Dimethylbutyl)-3-(2-fluoro-4-methyl-5-(7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl)phenyl)urea
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|
C23H29FN6O
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0664425
|
1-(2-fluoro-4-methyl-5-(2-methyl-7-(methylamino)-1,6-naphthyridin-3-yl)phenyl)-3-((S)-2-hydroxy-3,3-dimethylbutyl)urea
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|
C24H30FN5O2
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0672878
|
1-(3,3-dimethylbutyl)-3-(4-methyl-3-(2-methyl-7-(methylamino)-1,6-naphthyridin-3-yl)phenyl)urea
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|
C24H31N5O
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0095082
|
DABRAFENIB
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|
C23H20F3N5O2S2
|
1
|
| 1 |
IC50 = 5880 nM
|
|
|
|
CP0006321
|
PLX-4032
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|
C23H18ClF2N3O3S
|
1
|
| 1 |
IC50 = 16600 nM
|
|
|
