Brief Information of the Cell Line and Protein
Cell Line ID: CL000067 , HCT 116
 Cell Line Info 
Synonyms
HCT-116
HCT.116
HCT_116
HCT116
HCT116wt
CoCL2
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0291
Protein ID: PT02000 , TRAF2 and NCK-interacting protein kinase
 Protein Info 
Gene Name TNIK
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID Q9UKE5
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000067
 Cell Line Info 
 Protein ID: PT02000
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0018775
 Compound Info 
2-[3-[5-chloro-2-[3-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetonitrile
   Show/Hide
C24H25ClN6O
  1
1
IC50 = 5.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0004106
 Compound Info 
(2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one
   Show/Hide
C28H26N4O3
  1
1
IC50 = 39 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0367791
 Compound Info 
3-[2-[4-[4-(dimethylamino)piperidin-1-yl]-3-fluoroanilino]pyridin-4-yl]-4-methoxybenzonitrile
   Show/Hide
C26H28FN5O
  1
1
IC50 = 3100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0331513
 Compound Info 
4-methoxy-3-[2-(3-methoxy-4-morpholin-4-ylanilino)pyridin-4-yl]benzonitrile
   Show/Hide
C24H24N4O3
  1
1
IC50 = 6300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0156212
 Compound Info 
4-(5-chloro-2-methoxyphenyl)-N-[3-methoxy-4-(4-methylpiperazin-1-yl)phenyl]pyridin-2-amine
   Show/Hide
C24H27ClN4O2
  1
1
IC50 = 7900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0129667
 Compound Info 
4-methoxy-3-[2-(4-morpholin-4-ylanilino)pyridin-4-yl]benzonitrile
   Show/Hide
C23H22N4O2
  1
1
IC50 = 26000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0019097
 Compound Info 
3-[2-[3-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyridin-4-yl]benzonitrile
   Show/Hide
C24H25N5O
  1
1
IC50 = 27000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0156213
 Compound Info 
4-methoxy-3-[2-[4-(4-methylpiperazin-1-yl)anilino]pyridin-4-yl]benzonitrile
   Show/Hide
C24H25N5O
  1
1
IC50 > 30000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS