| Compound ID |
Compound Name |
Compound Formula |
|
CP0391331
|
US10479788, Example 175
Show/Hide
|
C22H26N8O
|
1
|
| 1 |
IC50 = 3.5 nM
|
|
|
|
CP0471512
|
US10399974, Example 54
Show/Hide
|
C25H32N8O
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0473781
|
US9409907, 179
Show/Hide
|
C23H28N8O
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0529342
|
N2-(4-(4,5-dimethyl-4H-1,2,4-triazol-3-yl)-2-ethoxyphenyl)-6-methyl-N8-neopentylpyrido[3,4-d]pyrimidine-2,8-diamine
Show/Hide
|
C25H32N8O
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0529341
|
N-(2-ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)phenyl)-6-methyl-8-(7-oxa-2-azaspiro[3.5]nonan-2-yl)pyrido[3,4-d]pyrimidin-2-amine
Show/Hide
|
C26H30N8O2
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0578491
|
8-(3,3-dimethylazetidin-1-yl)-N-[2-ethoxy-4-(4-methyl-1,2,4-triazol-3-yl)phenyl]-6-methylpyrido[3,4-d]pyrimidin-2-amine
Show/Hide
|
C24H28N8O
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0030809
|
tert-butyl 6-[2-chloro-4-(3-methylimidazol-4-yl)anilino]-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
Show/Hide
|
C26H26ClN7O2
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0484333
|
US11046688, Example 50
Show/Hide
|
C24H29N7O
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0033865
|
US10479788, Example 77
Show/Hide
|
C24H29N7O
|
1
|
| 1 |
IC50 = 59 nM
|
|
|
|
CP0139457
|
US10479788, Example 182
Show/Hide
|
C24H30N8O
|
1
|
| 1 |
IC50 = 63 nM
|
|
|
|
CP0322505
|
US11046688, Example 49
Show/Hide
|
C24H29N7O
|
1
|
| 1 |
IC50 = 95 nM
|
|
|
|
CP0405043
|
1-(2-((2-ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)phenyl)amino)-6-methylpyrido[3,4-d]pyrimidin-8-yl)-3-methylazetidine-3-carbonitrile
Show/Hide
|
C24H25N9O
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0416442
|
US10479788, Example 68
Show/Hide
|
C23H27N7O
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0020307
|
tert-butyl 6-[2-chloro-4-(1-methylpyrazol-4-yl)anilino]-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
Show/Hide
|
C26H26ClN7O2
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0027579
|
N-(2,6-diethylphenyl)-1-methyl-8-[4-[(1-methylpiperidin-4-yl)carbamoyl]-2-(trifluoromethoxy)anilino]-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamide
Show/Hide
|
C35H39F3N8O3
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0093675
|
US10479788, Example 177
Show/Hide
|
C25H31N7O
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0409723
|
US10479788, Example 76
Show/Hide
|
C24H29N7O
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0024475
|
tert-butyl 6-(2-chloro-4-pyrimidin-5-ylanilino)-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
Show/Hide
|
C26H24ClN7O2
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0329773
|
US10479788, Example 55
Show/Hide
|
C24H27N7O
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0023726
|
tert-butyl 6-[4-(azetidine-1-carbonyl)-2-chloroanilino]-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
Show/Hide
|
C26H27ClN6O3
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0322590
|
US11046688, Example 48
Show/Hide
|
C24H29N7O
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0391330
|
2-N-[4-[5-[2-(dimethylamino)ethyl]-4-methyl-1,2,4-triazol-3-yl]-2-ethoxyphenyl]-8-N-(2,2-dimethylpropyl)-6-methylpyrido[3,4-d]pyrimidine-2,8-diamine
Show/Hide
|
C28H39N9O
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0405044
|
2-N-[4-(6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-3-yl)-2-methoxyphenyl]-8-N-(2,2-dimethylpropyl)-6-methylpyrido[3,4-d]pyrimidine-2,8-diamine
Show/Hide
|
C25H30N8O
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0473799
|
2-N-[4-(6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-3-yl)-2-ethoxyphenyl]-8-N-(2,2-dimethylpropyl)-6-methylpyrido[3,4-d]pyrimidine-2,8-diamine
Show/Hide
|
C26H32N8O
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0030810
|
tert-butyl 6-[2-chloro-4-(1,3-oxazol-5-yl)anilino]-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
Show/Hide
|
C25H23ClN6O3
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0484332
|
US10399974, Example 56
Show/Hide
|
C23H26N8O
|
1
|
| 1 |
IC50 = 370 nM
|
|
|
|
CP0380193
|
US10479788, Example 58
Show/Hide
|
C22H23N7O
|
1
|
| 1 |
IC50 = 430 nM
|
|
|
|
CP0464249
|
US10479788, Example 34
Show/Hide
|
C24H20N6O
|
1
|
| 1 |
IC50 = 480 nM
|
|
|
|
CP0023705
|
4-[[4-amino-6-(tert-butylamino)-5-cyanopyridin-2-yl]amino]benzamide
Show/Hide
|
C17H20N6O
|
1
|
| 1 |
IC50 = 560 nM
|
|
|
|
CP0023842
|
tert-butyl 6-[2-chloro-4-(dimethylcarbamoyl)anilino]-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
Show/Hide
|
C25H27ClN6O3
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0380192
|
US11046688, Example 32
Show/Hide
|
C22H20N8O
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0016088
|
tert-butyl 6-(2-chloro-4-pyrazin-2-ylanilino)-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
Show/Hide
|
C26H24ClN7O2
|
1
|
| 1 |
IC50 = 620 nM
|
|
|
|
CP0322506
|
US10479788, Example 65
Show/Hide
|
C22H25N7O
|
1
|
| 1 |
IC50 = 650 nM
|
|
|
|
CP0022007
|
tert-butyl 6-(2-chloro-4-pyridin-3-ylanilino)-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
Show/Hide
|
C27H25ClN6O2
|
1
|
| 1 |
IC50 = 710 nM
|
|
|
|
CP0024754
|
tert-butyl 6-[2-chloro-4-(4-methoxypiperidine-1-carbonyl)anilino]-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
Show/Hide
|
C29H33ClN6O4
|
1
|
| 1 |
IC50 = 720 nM
|
|
|
|
CP0032521
|
9-cyclopentyl-2-[2-methoxy-4-(1-methylpiperidin-4-yl)oxyanilino]-7-methylpurin-8-one
Show/Hide
|
C24H32N6O3
|
1
|
| 1 |
IC50 = 720 nM
|
|
|
|
CP0022008
|
tert-butyl 6-[2-chloro-4-(dimethylsulfamoyl)anilino]-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
Show/Hide
|
C24H27ClN6O4S
|
1
|
| 1 |
IC50 = 840 nM
|
|
|
|
CP0029562
|
tert-butyl 6-[2-chloro-4-(1,1-dioxo-1,4-thiazinane-4-carbonyl)anilino]-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
Show/Hide
|
C27H29ClN6O5S
|
1
|
| 1 |
IC50 = 860 nM
|
|
|
|
CP0030351
|
tert-butyl 6-[2-chloro-4-[4-(dimethylamino)piperidine-1-carbonyl]anilino]-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
Show/Hide
|
C30H36ClN7O3
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0455282
|
US10479788, Example 37
Show/Hide
|
C22H23N7O
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0020468
|
tert-butyl 6-[2-chloro-4-(1-methylpyrazol-3-yl)anilino]-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
Show/Hide
|
C26H26ClN7O2
|
1
|
| 1 |
IC50 = 2500 nM
|
|
|
|
CP0510841
|
US11046688, Example 95
Show/Hide
|
C22H20N8
|
1
|
| 1 |
IC50 = 2540 nM
|
|
|
|
CP0409721
|
US11046688, Example 96
Show/Hide
|
C23H22N8O
|
1
|
| 1 |
IC50 = 2640 nM
|
|
|
|
CP0218744
|
US11046688, Example 30
Show/Hide
|
C21H20N4O2
|
1
|
| 1 |
IC50 = 2770 nM
|
|
|
|
CP0020250
|
tert-butyl 6-(2-chloroanilino)-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
Show/Hide
|
C22H22ClN5O2
|
1
|
| 1 |
IC50 = 3400 nM
|
|
|
|
CP0431816
|
US10399974, Example 42
Show/Hide
|
C24H28N8O
|
1
|
| 1 |
IC50 = 3800 nM
|
|
|
|
CP0029560
|
3-chloro-N,N-dimethyl-4-[[2-(1-methylpyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-yl]amino]benzamide
Show/Hide
|
C20H19ClN6O
|
1
|
| 1 |
IC50 = 4100 nM
|
|
|
|
CP0380191
|
N-(2,4-dimethoxyphenyl)-8-(1-methylpyrazol-4-yl)pyrido[3,4-d]pyrimidin-2-amine
Show/Hide
|
C19H18N6O2
|
1
|
| 1 |
IC50 = 4840 nM
|
|
|
|
CP0023441
|
tert-butyl 6-[2-chloro-4-(dimethylcarbamoyl)anilino]-2-(1,3-oxazol-5-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
Show/Hide
|
C24H24ClN5O4
|
1
|
| 1 |
IC50 = 5600 nM
|
|
|
|
CP0020306
|
N-[2-chloro-4-(1-methylpyrazol-4-yl)phenyl]-2-(1-methylpyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-amine
Show/Hide
|
C21H18ClN7
|
1
|
| 1 |
IC50 = 6900 nM
|
|
|
|
CP0509105
|
US10479788, Example 35
Show/Hide
|
C21H20N6O
|
1
|
| 1 |
IC50 = 7810 nM
|
|
|
|
CP0452275
|
N-(4-methoxyphenyl)-8-(1-methylpyrazol-4-yl)pyrido[3,4-d]pyrimidin-2-amine
Show/Hide
|
C18H16N6O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
