Brief Information of the Compound and Protein
Compound Name
N-(2,4-dimethoxyphenyl)-8-(1-methylpyrazol-4-yl)pyrido[3,4-d]pyrimidin-2-amine
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PubChem ID
CID: 119025603
Canonical SMILES
COc1ccc(Nc2ncc3ccnc(-c4cnn(C)c4)c3n2)c(OC)c1
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Compound Formula C19H18N6O2
Compound Structure
Protein Name
Dual specificity protein kinase TTK
Protein Classification
Enzyme
>
Kinase
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Protein Kinase
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Other protein kinase group
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Other protein kinase TTK family
Uniprot ID
P33981
Gene Name
TTK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000067 HCT 116 Homo sapiens (Human)  1
1
IC50 = 4840 nM
   TI
   LI
   LO
   TS
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 46 nM
   TI
   LI
   LO
   TS