Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[[4-amino-6-(tert-butylamino)-5-cyanopyridin-2-yl]amino]benzamide
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 PubChem ID
CID: 70682875
SID: 163439441
Canonical SMILES
CC(C)(C)Nc1nc(Nc2ccc(cc2)C(N)=O)cc(N)c1C#N
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Compound Formula C17H20N6O
Compound Structure
Protein Name
 Protein Info 
Dual specificity protein kinase TTK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Other protein kinase group
>
Other protein kinase TTK family
Uniprot ID
P33981
Gene Name
TTK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000067 HCT 116
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 560 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 11 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 6.4 nM