Brief Information of the Compound and Protein
Compound Name
1-[4-[2-[(5-chloro-6-phenylfuro[2,3-d]pyrimidin-4-yl)amino]ethyl]phenyl]-3-phenylurea
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PubChem ID
CID: 44470318
SID: 85750207
Canonical SMILES
Clc1c(oc2ncnc(NCCc3ccc(NC(=O)Nc4ccccc4)cc3)c12)-c1ccccc1
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Compound Formula C27H22ClN5O2
Compound Structure
Protein Name
Aurora kinase A
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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Other protein kinase group
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Other protein kinase AUR family
Uniprot ID
O14965
Gene Name
AURKA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000067 HCT 116 Homo sapiens (Human)  1
1
IC50 = 389.6 nM
   TI
   LI
   LO
   TS
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 52 nM
   TI
   LI
   LO
   TS