Brief Information of the Cell Line and Protein
Cell Line ID: CL000067 , HCT 116
 Cell Line Info 
Synonyms
HCT-116
HCT.116
HCT_116
HCT116
HCT116wt
CoCL2
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0291
Protein ID: PT01466 , Telomerase reverse transcriptase
 Protein Info 
Gene Name TERT
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID O14746
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000067
 Cell Line Info 
 Protein ID: PT01466
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0781525
 Compound Info 
1-[[1-[(2S,3R,5R)-2-(hydroxymethyl)-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)tetrahydrofuran-3-yl]triazol-4-yl]methyl]-3-(3-sulfamoylphenyl)urea
   Show/Hide
C20H24N8O7S
  1
1
IC50 = 850 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0964507
 Compound Info 
4-[[1-[(2S,3R,5R)-2-(hydroxymethyl)-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)tetrahydrofuran-3-yl]triazol-4-yl]methoxy]benzenesulfonamide
   Show/Hide
C19H22N6O7S
  1
1
IC50 = 4800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0913154
 Compound Info 
[1-[(2S,3R,5R)-2-(hydroxymethyl)-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)tetrahydrofuran-3-yl]triazol-4-yl]methyl 4-sulfamoylbenzoate
   Show/Hide
C20H22N6O8S
  1
1
IC50 = 5600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0781526
 Compound Info 
1-[(2R,4R,5S)-5-(hydroxymethyl)-4-[4-[(2-oxochromen-6-yl)oxymethyl]triazol-1-yl]tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione
   Show/Hide
C22H21N5O7
  1
1
IC50 = 5700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0917647
 Compound Info 
1-[(2R,4R,5S)-4-[4-[(2,2-dioxo-1,2$l^6-benzoxathiin-6-yl)oxymethyl]triazol-1-yl]-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione
   Show/Hide
C21H21N5O8S
  1
1
IC50 = 48400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS