General Information of the Protein
Protein ID
PT01640
Protein Name
Transketolase
Gene Name
TKT
Sequence
MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKSQDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHPVPKQAFTDVATGSLGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQAKHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAELLKMFGIDRDAIAQAVRGLITKA
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Organism
Homo sapiens, Human
Protein Classification
Enzyme
>
Transferase
Function
Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
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Uniprot ID
Primary ID:
P29401

Secondarily ID:
A8K089
B4DE31
E7EPA7
Q8TBA3
Q96HH3
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Ensembl ID
ENSG00000163931
HGNC ID
HGNC:11834
Map of Molecular Bioactivity Related to the Protein
Map of Molecular Bioactivity Related to the Protein

Protein
Cell Line
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000067 , HCT 116
 Cell Line Info 
Compound ID Compound Name Compound Formula
CP0528205
 Compound Info 
2-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethyl acetate
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C15H20N3O2S+
  1
1
EC50 = 4.7 nM
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CP0371716
 Compound Info 
3-(acetylthio)-4-(N-((2-amino-6-methylpyridin-3-yl)methyl)formamido)pent-3-enyl acetate
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C17H23N3O4S
  1
1
EC50 = 8 nM
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CP0501701
 Compound Info 
N-[(2-amino-6-chloropyridin-3-yl)methyl]-N-[(Z)-3-[[(Z)-2-[(2-amino-6-chloropyridin-3-yl)methyl-formylamino]-5-hydroxypent-2-en-3-yl]disulfanyl]-5-hydroxypent-2-en-2-yl]formamide
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C24H30Cl2N6O4S2
  1
1
EC50 = 8 nM
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CP0195673
 Compound Info 
2-[3-[(2-amino-4,6-dimethylpyridin-3-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
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C14H20N3OS+
  1
1
EC50 = 8.3 nM
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CP0195675
 Compound Info 
2-[3-[(2-amino-6-ethylpyridin-3-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
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C14H20N3OS+
  1
1
EC50 = 8.7 nM
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CP0920865
 Compound Info 
3-(2-amino-6-chloro-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-thiazol-3-ium chloride
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C12H15Cl2N3OS
  1
1
EC50 = 9 nM
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CP0082026
 Compound Info 
3-(2-amino-6-chloro-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-thiazol-3-ium; chloride
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C12H15ClN3OS+
  1
1
EC50 = 9 nM
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CP0490415
 Compound Info 
N-[(2-amino-6-methylpyridin-3-yl)methyl]-N-[(Z)-3-[[(Z)-2-[(2-amino-6-methylpyridin-3-yl)methyl-formylamino]-5-hydroxypent-2-en-3-yl]disulfanyl]-5-hydroxypent-2-en-2-yl]formamide
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C26H36N6O4S2
  1
1
EC50 = 12 nM
 Bioactivity Info 
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CP0507855
 Compound Info 
N-[(2-amino-6-methylpyridin-3-yl)methyl]-N-[(Z)-5-hydroxy-3-(2-hydroxyethyldisulfanyl)pent-2-en-2-yl]formamide
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C15H23N3O3S2
  1
1
EC50 = 13 nM
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CP0474434
 Compound Info 
N-[(2-amino-6-methylpyridin-3-yl)methyl]-N-[(1Z)-1-(2-oxo-1,3-oxathian-4-ylidene)ethyl]formamide
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C14H17N3O3S
  1
1
EC50 = 15 nM
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CP0749247
 Compound Info 
3-(2-amino-6-methyl-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-thiazol-3-ium chloride
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C13H18ClN3OS
  2
1
EC50 = 18 nM
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2
EC50 = 26 nM
 Bioactivity Info 
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CP0229650
 Compound Info 
2-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-2-ethyl-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
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C15H22N3OS+
  1
1
EC50 = 21 nM
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CP0552943
 Compound Info 
4-(N-((2-amino-6-methylpyridin-3-yl)methyl)formamido)-3-(benzoylthio)pent-3-enyl benzoate
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C27H27N3O4S
  1
1
EC50 = 28 nM
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CP0920866
 Compound Info 
3-(2-amino-6-methyl-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)-2,4-dimethyl-thiazol-3-ium chloride
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C14H20ClN3OS
  1
1
EC50 = 28 nM
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CP0310680
 Compound Info 
1-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium-2-yl]ethanol
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C15H22N3O2S+
  1
1
EC50 = 30 nM
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CP0501702
 Compound Info 
N-[(Z)-3-[[(Z)-2-[acetyl-[(2-amino-6-methylpyridin-3-yl)methyl]amino]-5-hydroxypent-2-en-3-yl]disulfanyl]-5-hydroxypent-2-en-2-yl]-N-[(2-amino-6-methylpyridin-3-yl)methyl]acetamide
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C28H40N6O4S2
  1
1
EC50 = 32 nM
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CP0310682
 Compound Info 
(1R)-1-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethane-1,2-diol
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C13H18N3O2S+
  1
1
EC50 = 50 nM
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CP0371715
 Compound Info 
3-(2-(4-(N-((2-amino-6-methylpyridin-3-yl)methyl)formamido)-1-hydroxypent-3-en-3-yl)disulfanyl)propanoic acid
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C16H23N3O4S2
  1
1
EC50 = 52 nM
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CP0082024
 Compound Info 
3-(2-amino-6-methyl-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)-2,4-dimethyl-thiazol-3-ium; chloride
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C14H20N3OS+
  1
1
EC50 = 56 nM
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CP0955934
 Compound Info 
3-(2-amino-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-thiazol-3-ium chloride
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C12H16ClN3OS
  1
1
EC50 = 110 nM
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CP0364425
 Compound Info 
3-(2-amino-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-thiazol-3-ium; chloride
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C12H16N3OS+
  1
1
EC50 = 110 nM
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CP0474433
 Compound Info 
(4-(N-((2-amino-6-methylpyridin-3-yl)methyl)formamido)-1-hydroxypent-3-en-3-ylthio)methyl pivalate
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C19H29N3O4S
  1
1
EC50 = 116 nM
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CP0364427
 Compound Info 
2-[3-[[2-amino-6-(trifluoromethyl)pyridin-3-yl]methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
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C13H15F3N3OS+
  1
1
EC50 = 160 nM
 Bioactivity Info 
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CP0801258
 Compound Info 
3-(2-amino-6-methyl-pyridin-3-ylmethyl)-5-(1,2-dihydroxy-ethyl)-4-methyl-thiazol-3-ium
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C13H18N3O2S+
  1
1
EC50 = 300 nM
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CP0195676
 Compound Info 
6-amino-5-[[5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium-3-yl]methyl]pyridine-2-carbonitrile
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C13H15N4OS+
  1
1
EC50 = 360 nM
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CP0195672
 Compound Info 
2-[4-methyl-3-[[6-(trifluoromethyl)pyridin-3-yl]methyl]-1,3-thiazol-3-ium-5-yl]ethanol
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C13H14F3N2OS+
  1
1
EC50 = 470 nM
 Bioactivity Info 
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CP0513775
 Compound Info 
N-[(2-aminopyridin-3-yl)methyl]-N-[(Z)-3-[[(Z)-2-[(2-aminopyridin-3-yl)methyl-formylamino]-5-hydroxypent-2-en-3-yl]disulfanyl]-5-hydroxypent-2-en-2-yl]formamide
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C24H32N6O4S2
  1
1
EC50 = 479 nM
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CP0344464
 Compound Info 
2-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-2-methyl-1,3-thiazol-3-ium-5-yl]ethanol
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C13H18N3OS+
  1
1
EC50 = 490 nM
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CP0309223
 Compound Info 
2-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-4-(hydroxymethyl)-1,3-thiazol-3-ium-5-yl]ethanol
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C13H18N3O2S+
  1
1
EC50 = 570 nM
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CP0176557
 Compound Info 
2-[4-[(4-amino-2-cyclopropylpyrimidin-5-yl)methyl]-3-methylthiophen-2-yl]ethanol
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C15H19N3OS
  1
1
EC50 = 660 nM
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CP0364428
 Compound Info 
N-[6-amino-5-[[5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium-3-yl]methyl]pyridin-2-yl]acetamide
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C14H19N4O2S+
  1
1
EC50 = 800 nM
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CP0538625
 Compound Info 
2-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-4-methyl-2-(pyridin-3-ylmethyl)-1,3-thiazol-3-ium-5-yl]ethanol
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C19H23N4OS+
  1
1
EC50 = 840 nM
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CP0310681
 Compound Info 
2-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-4-ethyl-1,3-thiazol-3-ium-5-yl]ethanol
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C14H20N3OS+
  1
1
EC50 = 950 nM
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CP0364426
 Compound Info 
2-[3-[(2-amino-5-iodopyridin-3-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
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C12H15IN3OS+
  1
1
EC50 = 1000 nM
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CP0524215
 Compound Info 
2-[5-[(4-amino-2-methylpyrimidin-5-yl)methyl]-1,4-dimethylpyrazol-3-yl]ethanol
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C13H19N5O
  1
1
EC50 = 1100 nM
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CP0103064
 Compound Info 
3-Deazathiamine
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C13H17N3OS
  1
1
EC50 = 1200 nM
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CP0471413
 Compound Info 
3-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]propan-1-ol
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C14H20N3OS+
  1
1
EC50 = 1300 nM
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CP0344588
 Compound Info 
2-[3-[(6-aminopyridin-3-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
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C12H16N3OS+
  1
1
EC50 = 1600 nM
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CP0103322
 Compound Info 
(1S)-1-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethane-1,2-diol
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C13H18N3O2S+
  1
1
EC50 = 2000 nM
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CP0560124
 Compound Info 
3-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]propanenitrile
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C14H17N4S+
  1
1
EC50 = 2200 nM
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CP0528262
 Compound Info 
methyl 3-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]propanoate
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C15H20N3O2S+
  1
1
EC50 = 2300 nM
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CP0195644
 Compound Info 
2-[4-[(4-amino-2-propan-2-ylpyrimidin-5-yl)methyl]-3-methylthiophen-2-yl]ethanol
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C15H21N3OS
  1
1
EC50 = 2600 nM
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CP0103062
 Compound Info 
3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-2-one
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C12H16N4O2S
  1
1
EC50 = 2710 nM
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CP0310683
 Compound Info 
2-[5-[[5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium-3-yl]methyl]pyridine-2-carbonyl]benzoic acid
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C20H19N2O4S+
  1
1
EC50 = 3100 nM
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CP0036857
 Compound Info 
3-[(2-amino-6-methylpyridin-3-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-2-one
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C13H17N3O2S
  1
1
EC50 = 3240 nM
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CP0525760
 Compound Info 
2-[5-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2,4-dimethylpyrazol-3-yl]ethanol
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C13H19N5O
  1
1
EC50 = 4700 nM
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CP0501700
 Compound Info 
N-[(2-amino-6-methylpyridin-3-yl)methyl]-N-[(Z)-3-butylsulfanyl-5-hydroxypent-2-en-2-yl]formamide
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C17H27N3O2S
  1
1
EC50 = 6000 nM
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CP0176556
 Compound Info 
N-[4-amino-5-[[5-(2-hydroxyethyl)-4-methylthiophen-3-yl]methyl]pyrimidin-2-yl]acetamide
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C14H18N4O2S
  1
1
EC50 = 6300 nM
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CP0502008
 Compound Info 
2-[4-[(2,4-diaminopyrimidin-5-yl)methyl]-3-methylthiophen-2-yl]ethanol
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C12H16N4OS
  1
1
EC50 = 8500 nM
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CP0256986
 Compound Info 
3-(2-amino-6-methyl-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)-thiazol-3-ium; chloride
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C12H16N3OS+
  1
1
EC50 = 9500 nM
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CP0913658
 Compound Info 
3-(2-amino-6-methyl-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)-thiazol-3-ium chloride
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C12H16ClN3OS
  1
1
EC50 = 9541 nM
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CP0336716
 Compound Info 
2-[4-[(4-amino-2-phenylpyrimidin-5-yl)methyl]-3-methylthiophen-2-yl]ethanol
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C18H19N3OS
  1
1
EC50 > 10000 nM
 Bioactivity Info 
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CP0502009
 Compound Info 
2-[5-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1H-pyrazol-3-yl]ethanol
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C12H17N5O
  1
1
EC50 = 17000 nM
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CP0195671
 Compound Info 
2-[3-[(4-aminopyridin-3-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
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C12H16N3OS+
  1
1
EC50 = 24000 nM
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CP0528261
 Compound Info 
2-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-2-(1,3-benzodioxol-5-yl)-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
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C20H22N3O3S+
  1
1
EC50 = 25000 nM
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CP0222617
 Compound Info 
2-[4-[[4-amino-2-(trifluoromethyl)pyrimidin-5-yl]methyl]-3-methylthiophen-2-yl]ethanol
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C13H14F3N3OS
  1
1
EC50 = 25000 nM
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CP0103325
 Compound Info 
2-[4-methyl-3-[(5-methylpyridin-3-yl)methyl]-1,3-thiazol-3-ium-5-yl]ethanol
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C13H17N2OS+
  1
1
EC50 = 38000 nM
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CP0059453
 Compound Info 
2-[4-[(4-aminopyrimidin-5-yl)methyl]-3-methylthiophen-2-yl]ethanol
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C12H15N3OS
  1
1
EC50 = 52000 nM
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Biochemical Assays
Compound ID Compound Name Compound Formula
CP0176556
 Compound Info 
N-[4-amino-5-[[5-(2-hydroxyethyl)-4-methylthiophen-3-yl]methyl]pyrimidin-2-yl]acetamide
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C14H18N4O2S
  2
1 Kd = 3 nM
2 Kd = 1100 nM
CP0344588
 Compound Info 
2-[3-[(6-aminopyridin-3-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
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C12H16N3OS+
  1
1 Kd = 7 nM
CP0195675
 Compound Info 
2-[3-[(2-amino-6-ethylpyridin-3-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
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C14H20N3OS+
  1
1 Kd = 10 nM
CP0103064
 Compound Info 
3-Deazathiamine
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C13H17N3OS
  2
1 Kd = 12 nM
2 Kd = 18000 nM
CP0364428
 Compound Info 
N-[6-amino-5-[[5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium-3-yl]methyl]pyridin-2-yl]acetamide
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C14H19N4O2S+
  1
1 Kd = 23 nM
CP0082024
 Compound Info 
3-(2-amino-6-methyl-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)-2,4-dimethyl-thiazol-3-ium; chloride
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C14H20N3OS+
  1
1 Kd = 25 nM
CP0309223
 Compound Info 
2-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-4-(hydroxymethyl)-1,3-thiazol-3-ium-5-yl]ethanol
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C13H18N3O2S+
  1
1 Kd = 25 nM
CP0103322
 Compound Info 
(1S)-1-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethane-1,2-diol
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C13H18N3O2S+
  1
1 Kd = 27 nM
CP0310682
 Compound Info 
(1R)-1-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethane-1,2-diol
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C13H18N3O2S+
  1
1 Kd = 28 nM
CP0256986
 Compound Info 
3-(2-amino-6-methyl-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)-thiazol-3-ium; chloride
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C12H16N3OS+
  1
1 Kd = 29 nM
CP0749247
 Compound Info 
3-(2-amino-6-methyl-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-thiazol-3-ium chloride
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C13H18ClN3OS
  1
1 Kd = 33 nM
CP0195673
 Compound Info 
2-[3-[(2-amino-4,6-dimethylpyridin-3-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
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C14H20N3OS+
  1
1 Kd = 34 nM
CP0344464
 Compound Info 
2-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-2-methyl-1,3-thiazol-3-ium-5-yl]ethanol
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C13H18N3OS+
  1
1 Kd = 36 nM
CP0364425
 Compound Info 
3-(2-amino-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-thiazol-3-ium; chloride
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C12H16N3OS+
  1
1 Kd = 36 nM
CP0310681
 Compound Info 
2-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-4-ethyl-1,3-thiazol-3-ium-5-yl]ethanol
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C14H20N3OS+
  1
1 Kd = 40 nM
CP0082026
 Compound Info 
3-(2-amino-6-chloro-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-thiazol-3-ium; chloride
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C12H15ClN3OS+
  1
1 Kd = 46 nM
CP0801258
 Compound Info 
3-(2-amino-6-methyl-pyridin-3-ylmethyl)-5-(1,2-dihydroxy-ethyl)-4-methyl-thiazol-3-ium
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C13H18N3O2S+
  1
1 Kd = 53 nM
CP0195676
 Compound Info 
6-amino-5-[[5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium-3-yl]methyl]pyridine-2-carbonitrile
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C13H15N4OS+
  1
1 Kd = 57 nM
CP0176557
 Compound Info 
2-[4-[(4-amino-2-cyclopropylpyrimidin-5-yl)methyl]-3-methylthiophen-2-yl]ethanol
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C15H19N3OS
  1
1 Kd = 60 nM
CP0222617
 Compound Info 
2-[4-[[4-amino-2-(trifluoromethyl)pyrimidin-5-yl]methyl]-3-methylthiophen-2-yl]ethanol
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C13H14F3N3OS
  1
1 Kd = 63 nM
CP0195671
 Compound Info 
2-[3-[(4-aminopyridin-3-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
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C12H16N3OS+
  1
1 Kd = 64 nM
CP0195644
 Compound Info 
2-[4-[(4-amino-2-propan-2-ylpyrimidin-5-yl)methyl]-3-methylthiophen-2-yl]ethanol
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C15H21N3OS
  1
1 Kd = 64 nM
CP0229650
 Compound Info 
2-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-2-ethyl-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
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C15H22N3OS+
  1
1 Kd = 75 nM
CP0364427
 Compound Info 
2-[3-[[2-amino-6-(trifluoromethyl)pyridin-3-yl]methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
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C13H15F3N3OS+
  1
1 Kd = 104 nM
CP0364426
 Compound Info 
2-[3-[(2-amino-5-iodopyridin-3-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
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C12H15IN3OS+
  1
1 Kd = 109 nM
CP0310680
 Compound Info 
1-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium-2-yl]ethanol
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C15H22N3O2S+
  1
1 Kd = 120 nM
CP0310683
 Compound Info 
2-[5-[[5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium-3-yl]methyl]pyridine-2-carbonyl]benzoic acid
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C20H19N2O4S+
  1
1 Kd = 140 nM
CP0103325
 Compound Info 
2-[4-methyl-3-[(5-methylpyridin-3-yl)methyl]-1,3-thiazol-3-ium-5-yl]ethanol
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C13H17N2OS+
  1
1 Kd = 220 nM
CP0336716
 Compound Info 
2-[4-[(4-amino-2-phenylpyrimidin-5-yl)methyl]-3-methylthiophen-2-yl]ethanol
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C18H19N3OS
  1
1 Kd = 230 nM
CP0195672
 Compound Info 
2-[4-methyl-3-[[6-(trifluoromethyl)pyridin-3-yl]methyl]-1,3-thiazol-3-ium-5-yl]ethanol
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C13H14F3N2OS+
  1
1 Kd = 310 nM
CP0502008
 Compound Info 
2-[4-[(2,4-diaminopyrimidin-5-yl)methyl]-3-methylthiophen-2-yl]ethanol
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C12H16N4OS
  1
1 Kd = 2200 nM
CP0103062
 Compound Info 
3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-2-one
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C12H16N4O2S
  1
1 Kd = 34000 nM
CP0059453
 Compound Info 
2-[4-[(4-aminopyrimidin-5-yl)methyl]-3-methylthiophen-2-yl]ethanol
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C12H15N3OS
  1
1 Kd > 100000 nM
Clinical Information about the Protein
Target 1 ( Transketolase (TK) )
Target Type Literature-reported Target