| Compound ID |
Compound Name |
Compound Formula |
|
CP0528205
|
2-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethyl acetate
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|
C15H20N3O2S+
|
1
|
| 1 |
EC50 = 4.7 nM
|
|
|
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CP0371716
|
3-(acetylthio)-4-(N-((2-amino-6-methylpyridin-3-yl)methyl)formamido)pent-3-enyl acetate
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|
C17H23N3O4S
|
1
|
| 1 |
EC50 = 8 nM
|
|
|
|
CP0501701
|
N-[(2-amino-6-chloropyridin-3-yl)methyl]-N-[(Z)-3-[[(Z)-2-[(2-amino-6-chloropyridin-3-yl)methyl-formylamino]-5-hydroxypent-2-en-3-yl]disulfanyl]-5-hydroxypent-2-en-2-yl]formamide
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|
C24H30Cl2N6O4S2
|
1
|
| 1 |
EC50 = 8 nM
|
|
|
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CP0195673
|
2-[3-[(2-amino-4,6-dimethylpyridin-3-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
Show/Hide
|
C14H20N3OS+
|
1
|
| 1 |
EC50 = 8.3 nM
|
|
|
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CP0195675
|
2-[3-[(2-amino-6-ethylpyridin-3-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
Show/Hide
|
C14H20N3OS+
|
1
|
| 1 |
EC50 = 8.7 nM
|
|
|
|
CP0920865
|
3-(2-amino-6-chloro-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-thiazol-3-ium chloride
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|
C12H15Cl2N3OS
|
1
|
| 1 |
EC50 = 9 nM
|
|
|
|
CP0082026
|
3-(2-amino-6-chloro-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-thiazol-3-ium; chloride
Show/Hide
|
C12H15ClN3OS+
|
1
|
| 1 |
EC50 = 9 nM
|
|
|
|
CP0490415
|
N-[(2-amino-6-methylpyridin-3-yl)methyl]-N-[(Z)-3-[[(Z)-2-[(2-amino-6-methylpyridin-3-yl)methyl-formylamino]-5-hydroxypent-2-en-3-yl]disulfanyl]-5-hydroxypent-2-en-2-yl]formamide
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|
C26H36N6O4S2
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0507855
|
N-[(2-amino-6-methylpyridin-3-yl)methyl]-N-[(Z)-5-hydroxy-3-(2-hydroxyethyldisulfanyl)pent-2-en-2-yl]formamide
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|
C15H23N3O3S2
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0474434
|
N-[(2-amino-6-methylpyridin-3-yl)methyl]-N-[(1Z)-1-(2-oxo-1,3-oxathian-4-ylidene)ethyl]formamide
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|
C14H17N3O3S
|
1
|
| 1 |
EC50 = 15 nM
|
|
|
|
CP0749247
|
3-(2-amino-6-methyl-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-thiazol-3-ium chloride
Show/Hide
|
C13H18ClN3OS
|
2
|
| 1 |
EC50 = 18 nM
|
|
|
| 2 |
EC50 = 26 nM
|
|
|
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CP0229650
|
2-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-2-ethyl-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
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|
C15H22N3OS+
|
1
|
| 1 |
EC50 = 21 nM
|
|
|
|
CP0552943
|
4-(N-((2-amino-6-methylpyridin-3-yl)methyl)formamido)-3-(benzoylthio)pent-3-enyl benzoate
Show/Hide
|
C27H27N3O4S
|
1
|
| 1 |
EC50 = 28 nM
|
|
|
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CP0920866
|
3-(2-amino-6-methyl-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)-2,4-dimethyl-thiazol-3-ium chloride
Show/Hide
|
C14H20ClN3OS
|
1
|
| 1 |
EC50 = 28 nM
|
|
|
|
CP0310680
|
1-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium-2-yl]ethanol
Show/Hide
|
C15H22N3O2S+
|
1
|
| 1 |
EC50 = 30 nM
|
|
|
|
CP0501702
|
N-[(Z)-3-[[(Z)-2-[acetyl-[(2-amino-6-methylpyridin-3-yl)methyl]amino]-5-hydroxypent-2-en-3-yl]disulfanyl]-5-hydroxypent-2-en-2-yl]-N-[(2-amino-6-methylpyridin-3-yl)methyl]acetamide
Show/Hide
|
C28H40N6O4S2
|
1
|
| 1 |
EC50 = 32 nM
|
|
|
|
CP0310682
|
(1R)-1-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethane-1,2-diol
Show/Hide
|
C13H18N3O2S+
|
1
|
| 1 |
EC50 = 50 nM
|
|
|
|
CP0371715
|
3-(2-(4-(N-((2-amino-6-methylpyridin-3-yl)methyl)formamido)-1-hydroxypent-3-en-3-yl)disulfanyl)propanoic acid
Show/Hide
|
C16H23N3O4S2
|
1
|
| 1 |
EC50 = 52 nM
|
|
|
|
CP0082024
|
3-(2-amino-6-methyl-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)-2,4-dimethyl-thiazol-3-ium; chloride
Show/Hide
|
C14H20N3OS+
|
1
|
| 1 |
EC50 = 56 nM
|
|
|
|
CP0955934
|
3-(2-amino-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-thiazol-3-ium chloride
Show/Hide
|
C12H16ClN3OS
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
|
CP0364425
|
3-(2-amino-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-thiazol-3-ium; chloride
Show/Hide
|
C12H16N3OS+
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
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CP0474433
|
(4-(N-((2-amino-6-methylpyridin-3-yl)methyl)formamido)-1-hydroxypent-3-en-3-ylthio)methyl pivalate
Show/Hide
|
C19H29N3O4S
|
1
|
| 1 |
EC50 = 116 nM
|
|
|
|
CP0364427
|
2-[3-[[2-amino-6-(trifluoromethyl)pyridin-3-yl]methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
Show/Hide
|
C13H15F3N3OS+
|
1
|
| 1 |
EC50 = 160 nM
|
|
|
|
CP0801258
|
3-(2-amino-6-methyl-pyridin-3-ylmethyl)-5-(1,2-dihydroxy-ethyl)-4-methyl-thiazol-3-ium
Show/Hide
|
C13H18N3O2S+
|
1
|
| 1 |
EC50 = 300 nM
|
|
|
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CP0195676
|
6-amino-5-[[5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium-3-yl]methyl]pyridine-2-carbonitrile
Show/Hide
|
C13H15N4OS+
|
1
|
| 1 |
EC50 = 360 nM
|
|
|
|
CP0195672
|
2-[4-methyl-3-[[6-(trifluoromethyl)pyridin-3-yl]methyl]-1,3-thiazol-3-ium-5-yl]ethanol
Show/Hide
|
C13H14F3N2OS+
|
1
|
| 1 |
EC50 = 470 nM
|
|
|
|
CP0513775
|
N-[(2-aminopyridin-3-yl)methyl]-N-[(Z)-3-[[(Z)-2-[(2-aminopyridin-3-yl)methyl-formylamino]-5-hydroxypent-2-en-3-yl]disulfanyl]-5-hydroxypent-2-en-2-yl]formamide
Show/Hide
|
C24H32N6O4S2
|
1
|
| 1 |
EC50 = 479 nM
|
|
|
|
CP0344464
|
2-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-2-methyl-1,3-thiazol-3-ium-5-yl]ethanol
Show/Hide
|
C13H18N3OS+
|
1
|
| 1 |
EC50 = 490 nM
|
|
|
|
CP0309223
|
2-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-4-(hydroxymethyl)-1,3-thiazol-3-ium-5-yl]ethanol
Show/Hide
|
C13H18N3O2S+
|
1
|
| 1 |
EC50 = 570 nM
|
|
|
|
CP0176557
|
2-[4-[(4-amino-2-cyclopropylpyrimidin-5-yl)methyl]-3-methylthiophen-2-yl]ethanol
Show/Hide
|
C15H19N3OS
|
1
|
| 1 |
EC50 = 660 nM
|
|
|
|
CP0364428
|
N-[6-amino-5-[[5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium-3-yl]methyl]pyridin-2-yl]acetamide
Show/Hide
|
C14H19N4O2S+
|
1
|
| 1 |
EC50 = 800 nM
|
|
|
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CP0538625
|
2-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-4-methyl-2-(pyridin-3-ylmethyl)-1,3-thiazol-3-ium-5-yl]ethanol
Show/Hide
|
C19H23N4OS+
|
1
|
| 1 |
EC50 = 840 nM
|
|
|
|
CP0310681
|
2-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-4-ethyl-1,3-thiazol-3-ium-5-yl]ethanol
Show/Hide
|
C14H20N3OS+
|
1
|
| 1 |
EC50 = 950 nM
|
|
|
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CP0364426
|
2-[3-[(2-amino-5-iodopyridin-3-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
Show/Hide
|
C12H15IN3OS+
|
1
|
| 1 |
EC50 = 1000 nM
|
|
|
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CP0524215
|
2-[5-[(4-amino-2-methylpyrimidin-5-yl)methyl]-1,4-dimethylpyrazol-3-yl]ethanol
Show/Hide
|
C13H19N5O
|
1
|
| 1 |
EC50 = 1100 nM
|
|
|
|
CP0103064
|
3-Deazathiamine
Show/Hide
|
C13H17N3OS
|
1
|
| 1 |
EC50 = 1200 nM
|
|
|
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CP0471413
|
3-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]propan-1-ol
Show/Hide
|
C14H20N3OS+
|
1
|
| 1 |
EC50 = 1300 nM
|
|
|
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CP0344588
|
2-[3-[(6-aminopyridin-3-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
Show/Hide
|
C12H16N3OS+
|
1
|
| 1 |
EC50 = 1600 nM
|
|
|
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CP0103322
|
(1S)-1-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethane-1,2-diol
Show/Hide
|
C13H18N3O2S+
|
1
|
| 1 |
EC50 = 2000 nM
|
|
|
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CP0560124
|
3-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]propanenitrile
Show/Hide
|
C14H17N4S+
|
1
|
| 1 |
EC50 = 2200 nM
|
|
|
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CP0528262
|
methyl 3-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]propanoate
Show/Hide
|
C15H20N3O2S+
|
1
|
| 1 |
EC50 = 2300 nM
|
|
|
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CP0195644
|
2-[4-[(4-amino-2-propan-2-ylpyrimidin-5-yl)methyl]-3-methylthiophen-2-yl]ethanol
Show/Hide
|
C15H21N3OS
|
1
|
| 1 |
EC50 = 2600 nM
|
|
|
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CP0103062
|
3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-2-one
Show/Hide
|
C12H16N4O2S
|
1
|
| 1 |
EC50 = 2710 nM
|
|
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CP0310683
|
2-[5-[[5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium-3-yl]methyl]pyridine-2-carbonyl]benzoic acid
Show/Hide
|
C20H19N2O4S+
|
1
|
| 1 |
EC50 = 3100 nM
|
|
|
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CP0036857
|
3-[(2-amino-6-methylpyridin-3-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-2-one
Show/Hide
|
C13H17N3O2S
|
1
|
| 1 |
EC50 = 3240 nM
|
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CP0525760
|
2-[5-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2,4-dimethylpyrazol-3-yl]ethanol
Show/Hide
|
C13H19N5O
|
1
|
| 1 |
EC50 = 4700 nM
|
|
|
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CP0501700
|
N-[(2-amino-6-methylpyridin-3-yl)methyl]-N-[(Z)-3-butylsulfanyl-5-hydroxypent-2-en-2-yl]formamide
Show/Hide
|
C17H27N3O2S
|
1
|
| 1 |
EC50 = 6000 nM
|
|
|
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CP0176556
|
N-[4-amino-5-[[5-(2-hydroxyethyl)-4-methylthiophen-3-yl]methyl]pyrimidin-2-yl]acetamide
Show/Hide
|
C14H18N4O2S
|
1
|
| 1 |
EC50 = 6300 nM
|
|
|
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CP0502008
|
2-[4-[(2,4-diaminopyrimidin-5-yl)methyl]-3-methylthiophen-2-yl]ethanol
Show/Hide
|
C12H16N4OS
|
1
|
| 1 |
EC50 = 8500 nM
|
|
|
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CP0256986
|
3-(2-amino-6-methyl-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)-thiazol-3-ium; chloride
Show/Hide
|
C12H16N3OS+
|
1
|
| 1 |
EC50 = 9500 nM
|
|
|
|
CP0913658
|
3-(2-amino-6-methyl-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)-thiazol-3-ium chloride
Show/Hide
|
C12H16ClN3OS
|
1
|
| 1 |
EC50 = 9541 nM
|
|
|
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CP0336716
|
2-[4-[(4-amino-2-phenylpyrimidin-5-yl)methyl]-3-methylthiophen-2-yl]ethanol
Show/Hide
|
C18H19N3OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
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CP0502009
|
2-[5-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1H-pyrazol-3-yl]ethanol
Show/Hide
|
C12H17N5O
|
1
|
| 1 |
EC50 = 17000 nM
|
|
|
|
CP0195671
|
2-[3-[(4-aminopyridin-3-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
Show/Hide
|
C12H16N3OS+
|
1
|
| 1 |
EC50 = 24000 nM
|
|
|
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CP0528261
|
2-[3-[(2-amino-6-methylpyridin-3-yl)methyl]-2-(1,3-benzodioxol-5-yl)-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
Show/Hide
|
C20H22N3O3S+
|
1
|
| 1 |
EC50 = 25000 nM
|
|
|
|
CP0222617
|
2-[4-[[4-amino-2-(trifluoromethyl)pyrimidin-5-yl]methyl]-3-methylthiophen-2-yl]ethanol
Show/Hide
|
C13H14F3N3OS
|
1
|
| 1 |
EC50 = 25000 nM
|
|
|
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CP0103325
|
2-[4-methyl-3-[(5-methylpyridin-3-yl)methyl]-1,3-thiazol-3-ium-5-yl]ethanol
Show/Hide
|
C13H17N2OS+
|
1
|
| 1 |
EC50 = 38000 nM
|
|
|
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CP0059453
|
2-[4-[(4-aminopyrimidin-5-yl)methyl]-3-methylthiophen-2-yl]ethanol
Show/Hide
|
C12H15N3OS
|
1
|
| 1 |
EC50 = 52000 nM
|
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