Brief Information of the Cell Line and Protein
Cell Line ID: CL000067 , HCT 116
 Cell Line Info 
Synonyms
HCT-116
HCT.116
HCT_116
HCT116
HCT116wt
CoCL2
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0291
Protein ID: PT01566 , Histone-lysine N-methyltransferase EHMT2
 Protein Info 
Gene Name EHMT2
Organism Homo sapiens, Human
Protein Classification Epigenetic regulator
Uniprot ID Q96KQ7
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000067
 Cell Line Info 
 Protein ID: PT01566
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0341308
 Compound Info 
N-[1-(cyclohexylmethyl)piperidin-4-yl]-6-methoxy-7-(3-piperidin-1-ylpropoxy)-2-(4-propan-2-yl-1,4-diazepan-1-yl)quinazolin-4-amine
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C37H61N7O2
  2
1
IC50 = 51 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 72 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0042224
 Compound Info 
N-(1-cyclohexylpiperidin-4-yl)-6-methoxy-7-(3-piperidin-1-ylpropoxy)-2-(4-propan-2-yl-1,4-diazepan-1-yl)quinazolin-4-amine
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C36H59N7O2
  2
1
IC50 = 68 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 86 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0046275
 Compound Info 
2-cyclohexyl-6-methoxy-N-(1-propan-2-ylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine
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C30H47N5O2
  2
1
IC50 = 210 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 240 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS