5-(4-Cyanophenyl)-2-ureidothiophene-3-carboxylic Acid(S)-Piperidin-3-ylamide Hydrochloride

4-[[(2R,3S)-2-methylpiperidin-3-yl]amino]-2-phenylthieno[3,2-c]pyridine-7-carboxamide

4-(1-methylpyrazol-4-yl)-12-[4-(piperidin-1-ylmethyl)phenyl]-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2,4,6,10,12-hexaene

AZD7762

5-(3-Chlorophenyl)-3-ureidothiophene-2-carboxylic Acid(S)-Piperidin-3-ylamide Hydrochloride

4-[[(2S,3S,6R)-2,6-dimethylpiperidin-3-yl]amino]-2-phenylthieno[3,2-c]pyridine-7-carboxamide

4-[[(3S)-piperidin-3-yl]amino]-2-thiophen-3-ylthieno[3,2-c]pyridine-7-carboxamide

4-[[(3S)-piperidin-3-yl]amino]-2-thiophen-2-ylthieno[3,2-c]pyridine-7-carboxamide

(S)-1-(5-phenyl-3-(piperidin-3-ylcarbamoyl)thiophen-2-yl)urea

5-(2-Fluorophenyl)-3-ureidothiophene-2-carboxylic Acid(S)-Piperidin-3-ylamide Hydrochloride

5-(2,4-Difluorophenyl)-3-ureidothiophene-2-carboxylic Acid(S)-Piperidin-3-ylamide Hydrochloride

5-(3-Fluorophenyl)-2-ureidothiophene-3-carboxylic Acid(S)-Piperidin-3-ylamide Hydrochloride

5-(4-Fluorophenyl)-3-ureidothiophene-2-carboxylic Acid(S)-Piperidin-3-ylamide Hydrochloride

5-Phenyl-3-ureidothiophene-2-carboxylic Acid(S)-Piperidin-3-ylamide Hydrochloride

5-[12-[4-(piperidin-1-ylmethyl)phenyl]-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2,4,6,10,12-hexaen-4-yl]-1,3-oxazole

2-(3-fluorophenyl)-4-[[(3S)-piperidin-3-yl]amino]thieno[3,2-c]pyridine-7-carboxamide

(S)-2-phenyl-4-(piperidin-3-ylamino)thieno[3,2-c]pyridine-7-carboxamide

5-(4-Cyanophenyl)-3-ureidothiophene-2-carboxylic Acid(S)-Piperidin-3-ylamide Hydrochloride

5-(4-Fluorophenyl)-2-ureidothiophene-3-carboxylic Acid(S)-Piperidin-3-ylamide Hydrochloride

5-(3,5-Difluorophenyl)-2-ureidothiophene-3-carboxylic Acid(S)-Piperidin-3-ylamide Hydrochloride

4-[[(3S,6R)-6-methylpiperidin-3-yl]amino]-2-phenylthieno[3,2-c]pyridine-7-carboxamide

2-(3-fluorophenyl)-4-[[(3S)-piperidin-3-yl]amino]-1H-indole-7-carboxamide

5-(3-Chlorophenyl)-2-ureidothiophene-3-carboxylic Acid(S)-Piperidin-3-ylamide Hydrochloride

5-(3-Cyanophenyl)-3-ureidothiophene-2-carboxylic Acid(S)-Piperidin-3-ylamide Hydrochloride

2-(4-fluorophenyl)-4-[[(3S)-piperidin-3-yl]amino]-1H-indole-7-carboxamide

4-[[(2S,3S)-2-methylpiperidin-3-yl]amino]-2-phenylthieno[3,2-c]pyridine-7-carboxamide

3-(5-Ethyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)-9H-pyrrolo[2,3-b:5,4-c']dipyridine-6-carbonitrile

2-phenyl-4-[[(3S)-piperidin-3-yl]amino]-1H-indole-7-carboxamide

12-[4-(piperidin-1-ylmethyl)phenyl]-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene-4-carbonitrile

5-(3,5-Difluorophenyl)-3-ureidothiophene-2-carboxylic Acid(S)-Piperidin-3-ylamide Hydrochloride

5-(2,3-Difluorophenyl)-3-ureidothiophene-2-carboxylic Acid(S)-Piperidin-3-ylamide Hydrochloride

2-(1-benzylpyrazol-4-yl)-4-[[(3S)-piperidin-3-yl]amino]thieno[3,2-c]pyridine-7-carboxamide

5-[12-[4-(piperidin-1-ylmethyl)phenyl]-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2,4,6,10,12-hexaen-4-yl]-1,3-thiazole

2-(4-chlorophenyl)-4-[[(3S)-piperidin-3-yl]amino]-1H-indole-7-carboxamide

3-(4-((2-Oxa-7-azaspiro[3.5]nonan-7-yl)methyl)phenyl)-9H-pyrrolo[2,3-b:5,4-c']-dipyridine-6-carbonitrile

12-[4-(piperidin-1-ylmethyl)phenyl]-4-pyridin-3-yl-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2,4,6,10,12-hexaene

5-(2-Fluorophenyl)-2-ureidothiophene-3-carboxylic Acid(S)-Piperidin-3-ylamide Hydrochloride

3-(4-((4-Fluoropiperidin-1-yl)methyl)phenyl)-9H-pyrrolo[2,3-b:5,4-c']dipyridine-6-carbonitrile

12-[4-(4-methylpiperazin-1-yl)phenyl]-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene-4-carbonitrile

3-(4-(((2R,6S)-2,6-Dimethylpiperidin-1-yl)methyl)phenyl)-9H-pyrrolo[2,3-b:5,4-c']dipyridine-6-carbonitrile

5-(2,3-Difluorophenyl)-2-ureidothiophene-3-carboxylic Acid(S)-Piperidin-3-ylamide Hydrochloride

2-[12-[4-(piperidin-1-ylmethyl)phenyl]-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2,4,6,10,12-hexaen-4-yl]-1,3,4-oxadiazole

4-[ethyl-[(3S)-piperidin-3-yl]amino]-2-phenylthieno[3,2-c]pyridine-7-carboxamide

(R)-3-(4-((3-Hydroxypiperidin-1-yl)methyl)phenyl)-9H-pyrrolo-[2,3-b:5,4-c']dipyridine-6-carbonitrile

12-[4-[(3,3-dimethylpiperidin-1-yl)methyl]phenyl]-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene-4-carbonitrile

12-[3-(4-methylpiperazin-1-yl)phenyl]-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene-4-carbonitrile

3-(4-((4-Hydroxypiperidin-1-yl)methyl)phenyl)-9H-pyrrolo[2,3-b:5,4-c']dipyridine-6-carbonitrile

4-[12-[4-(piperidin-1-ylmethyl)phenyl]-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2,4,6,10,12-hexaen-4-yl]-1,2-oxazole

5-(3,4-Dichlorophenyl)-2-ureidothiophene-3-carboxylic Acid(S)-Piperidin-3-ylamide Hydrochloride

2-(1-methylpyrazol-4-yl)-4-[[(3S)-piperidin-3-yl]amino]thieno[3,2-c]pyridine-7-carboxamide

3-(2-Ethyl-1,2,3,4-tetrahydroisoquinolin-6-yl)-9H-pyrrolo[2,3-b:5,4-c']dipyridine-6-carbonitrile

12-[4-(piperidin-1-ylmethyl)phenyl]-4-pyrimidin-5-yl-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2,4,6,10,12-hexaene

12-[4-(piperidin-1-ylmethyl)phenyl]-4-pyrazin-2-yl-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2,4,6,10,12-hexaene

3-(4-((4,4-Dimethylpiperidin-1-yl)methyl)phenyl)-9H-pyrrolo[2,3-b:5,4-c']dipyridine-6-carbonitrile

12-(furan-3-yl)-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene-4-carbonitrile

5-(2,4-Difluorophenyl)-2-ureidothiophene-3-carboxylic Acid(S)-Piperidin-3-ylamide Hydrochloride

5-(3,4-Dichlorophenyl)-3-ureidothiophene-2-carboxylic Acid(S)-Piperidin-3-ylamide Hydrochloride

3-(4-(((3R,5S)-3,5-Dimethylpiperidin-1-yl)methyl)phenyl)-9H-pyrrolo[2,3-b:5,4-c']-dipyridine-6-carbonitrile

2-phenyl-4-piperidin-3-ylsulfanylthieno[3,2-c]pyridine-7-carboxamide

3-(4-(Morpholinomethyl)phenyl)-9H-pyrrolo[2,3-b:5,4-c']-dipyridine-6-carbonitrile

12-(4-morpholin-4-ylphenyl)-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene-4-carbonitrile

3-(4-(2-(Piperidin-1-yl)propan-2-yl)phenyl)-9H-pyrrolo[2,3-b:5,4-c']dipyridine-6-carbonitrile

12-[4-(piperidin-1-ylmethyl)phenyl]-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2,4,6,10,12-hexaene-4-carboxamide

3-(4-((4-Cyanopiperidin-1-yl)methyl)phenyl)-9H-pyrrolo[2,3-b:5,4-c']dipyridine-6-carbonitrile

2-phenyl-4-[(3S)-piperidin-3-yl]oxythieno[3,2-c]pyridine-7-carboxamide

2-phenyl-4-[[(3S)-piperidin-3-yl]amino]furo[3,2-c]pyridine-7-carboxamide

4-[[(3S,4S)-4-hydroxypiperidin-3-yl]amino]-2-phenylthieno[3,2-c]pyridine-7-carboxamide

N-[3-(4-cyano-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-12-yl)phenyl]acetamide

[12-[4-(piperidin-1-ylmethyl)phenyl]-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-4-yl]methanol

12-thiophen-2-yl-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene-4-carbonitrile

3-(6-(Piperidin-1-ylmethyl)pyridin-3-yl)-9H-pyrrolo[2,3-b:5,4-c']-dipyridine-6-carbonitrile

12-[4-(piperidin-1-ylmethyl)phenyl]-4-pyridazin-4-yl-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2,4,6,10,12-hexaene

3-(4-(Piperidin-1-ylmethyl)thiazol-2-yl)-9H-pyrrolo[2,3-b:5,4-c']-dipyridine-6-carbonitrile

4-[methyl-[(3S)-piperidin-3-yl]amino]-2-phenylthieno[3,2-c]pyridine-7-carboxamide

4-[[(3S)-1-methylpiperidin-3-yl]amino]-2-phenylthieno[3,2-c]pyridine-7-carboxamide

12-[4-(hydroxymethyl)phenyl]-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene-4-carbonitrile

5-(3-Cyanophenyl)-2-ureidothiophene-3-carboxylic Acid(S)-Piperidin-3-ylamide Hydrochloride

4-methoxy-12-[4-(piperidin-1-ylmethyl)phenyl]-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2,4,6,10,12-hexaene

12-[4-(piperidin-1-ylmethyl)phenyl]-4-pyridin-4-yl-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2,4,6,10,12-hexaene

12-(ethylamino)-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene-4-carbonitrile

12-[4-(piperidin-1-ylmethyl)phenyl]-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene

N-ethyl-12-[4-(piperidin-1-ylmethyl)phenyl]-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2,4,6,10,12-hexaene-4-carboxamide

4-[[(3S)-piperidin-3-yl]amino]-2-(1H-pyrazol-4-yl)thieno[3,2-c]pyridine-7-carboxamide

12-(1-methylpyrazol-3-yl)-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene-4-carbonitrile

4-[[(2R,3S)-2-(2-hydroxyethyl)piperidin-3-yl]amino]-2-phenylthieno[3,2-c]pyridine-7-carboxamide

4-[2-hydroxyethyl-[(3S)-piperidin-3-yl]amino]-2-phenylthieno[3,2-c]pyridine-7-carboxamide

2-imidazol-1-yl-4-[[(3S)-piperidin-3-yl]amino]thieno[3,2-c]pyridine-7-carboxamide

12-(2-hydroxyphenyl)-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene-4-carbonitrile

12-(1H-imidazol-2-yl)-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene-4-carbonitrile

12-pyridin-3-yl-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene-4-carbonitrile

12-pyridin-2-yl-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene-4-carbonitrile

12-hydroxy-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene-4-carbonitrile

12-[3-(hydroxymethyl)phenyl]-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene-4-carbonitrile

12-pyridin-4-yl-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene-4-carbonitrile

5-[[5-cyclopropyl-4-(methylamino)pyridin-2-yl]amino]-3-[(2R)-1-(dimethylamino)propan-2-yl]oxypyrazine-2-carbonitrile

methyl 6-[(5-cyanopyrazin-2-yl)amino]-4-[[(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl]amino]pyridine-3-carboxylate

5-[[5-(5-methyl-1,3-thiazol-2-yl)-4-[[(2R)-morpholin-2-yl]methylamino]pyridin-2-yl]amino]pyrazine-2-carbonitrile

methyl 4-[[(1R,5S)-8-azabicyclo[3.2.1]octan-3-yl]amino]-6-[(5-cyanopyrazin-2-yl)amino]pyridine-3-carboxylate

3-[(2R)-1-(dimethylamino)propan-2-yl]oxy-5-[[4-(methylamino)-5-(1-methylpyrazol-4-yl)pyridin-2-yl]amino]pyrazine-2-carbonitrile

5-[[5-chloro-4-(methylamino)pyridin-2-yl]amino]-3-[(2R)-1-(dimethylamino)propan-2-yl]oxypyrazine-2-carbonitrile

3-[(2R)-1-(dimethylamino)propan-2-yl]oxy-5-[[4-(methylamino)-5-(trifluoromethyl)pyridin-2-yl]amino]pyrazine-2-carbonitrile

methyl 6-[[5-cyano-6-[(3R)-pyrrolidin-3-yl]oxypyrazin-2-yl]amino]-4-(methylamino)pyridine-3-carboxylate

3-[(2R)-1-(dimethylamino)propan-2-yl]oxy-5-[[4-methoxy-5-(1-methylpyrazol-4-yl)pyridin-2-yl]amino]pyrazine-2-carbonitrile

5-[[4-methoxy-5-(1-methylpyrazol-4-yl)pyridin-2-yl]amino]-3-[(3R)-pyrrolidin-3-yl]oxypyrazine-2-carbonitrile

5-[[4-[[(2R)-morpholin-2-yl]methylamino]-5-(trifluoromethyl)-2-pyridyl]amino]pyrazine-2-carbonitrile

methyl 6-[[5-cyano-6-[(2R)-1-(dimethylamino)propan-2-yl]oxypyrazin-2-yl]amino]-4-(methylamino)pyridine-3-carboxylate

3-[(2R)-1-(dimethylamino)propan-2-yl]oxy-5-[[5-ethynyl-4-(methylamino)pyridin-2-yl]amino]pyrazine-2-carbonitrile

5-[(8-chloroisoquinolin-3-yl)amino]-3-[(2R)-1-(dimethylamino)propan-2-yl]oxypyrazine-2-carbonitrile

5-[[4-methoxy-5-(1-methylpyrazol-4-yl)pyridin-2-yl]amino]-3-[(3R)-1-methylpyrrolidin-3-yl]oxypyrazine-2-carbonitrile

5-[[5-(1-methylpyrazol-4-yl)-4-[[(2R)-morpholin-2-yl]methylamino]pyridin-2-yl]amino]pyrazine-2-carbonitrile

3-[(2R)-1-(dimethylamino)propan-2-yl]oxy-5-[[5-(3-hydroxy-3-methylbut-1-ynyl)-4-(methylamino)pyridin-2-yl]amino]pyrazine-2-carbonitrile

5-[[5-[2-(1-hydroxycyclopentyl)ethynyl]-4-[[(2S)-morpholin-2-yl]methylamino]pyridin-2-yl]amino]pyrazine-2-carbonitrile

5-[[5-cyclopropyl-4-[[(2S)-morpholin-2-yl]methylamino]pyridin-2-yl]amino]pyrazine-2-carbonitrile

5-[[5-ethynyl-4-[[(2S)-morpholin-2-yl]methylamino]pyridin-2-yl]amino]pyrazine-2-carbonitrile

5-[[4-(methylamino)-5-(1-methylpyrazol-4-yl)pyridin-2-yl]amino]-3-[(3R)-1-methylpyrrolidin-3-yl]oxypyrazine-2-carbonitrile

3-[(2R)-1-(dimethylamino)propan-2-yl]oxy-5-[[5-(1-methylpyrazol-4-yl)-4-methylsulfanylpyridin-2-yl]amino]pyrazine-2-carbonitrile

5-[[5-(3-fluorophenyl)-4-[[(2R)-morpholin-2-yl]methylamino]pyridin-2-yl]amino]pyrazine-2-carbonitrile

3-[(2R)-1-(dimethylamino)propan-2-yl]oxy-5-[[5-(3-fluorophenyl)-4-(methylamino)pyridin-2-yl]amino]pyrazine-2-carbonitrile

3-[(2R)-1-(dimethylamino)propan-2-yl]oxy-5-[[4-(methylamino)pyridin-2-yl]amino]pyrazine-2-carbonitrile

methyl 6-[(5-cyanopyrazin-2-yl)amino]-4-[(1-methylpiperidin-4-yl)amino]pyridine-3-carboxylate

5-[[4-(methylamino)-5-(1-methylpyrazol-4-yl)pyridin-2-yl]amino]-3-[(3S)-1-methylpyrrolidin-3-yl]oxypyrazine-2-carbonitrile

5-[[5-chloro-4-[[(2R)-morpholin-2-yl]methylamino]pyridin-2-yl]amino]pyrazine-2-carbonitrile

1137478-46-6

methyl 6-[[5-cyano-6-[(3R)-pyrrolidin-3-yl]oxypyrazin-2-yl]amino]-4-(dimethylamino)pyridine-3-carboxylate

5-[[4-(methylamino)-5-(1-methylpyrazol-4-yl)pyridin-2-yl]amino]-3-[(3S)-pyrrolidin-3-yl]oxypyrazine-2-carbonitrile

5-[[4-(methylamino)-5-(1-methylpyrazol-4-yl)pyridin-2-yl]amino]-3-[(3R)-pyrrolidin-3-yl]oxypyrazine-2-carbonitrile

5-[[5-(1-methylindazol-5-yl)-4-[[(2R)-morpholin-2-yl]methylamino]pyridin-2-yl]amino]pyrazine-2-carbonitrile

1137478-52-4

1137477-07-6

methyl 6-[[5-cyano-6-[(3R)-pyrrolidin-3-yl]oxypyrazin-2-yl]amino]-4-methylsulfanylpyridine-3-carboxylate

1137478-41-1

1137478-45-5

5-[[5-phenyl-4-(piperidin-4-ylmethylamino)pyridin-2-yl]amino]pyrazine-2-carbonitrile

methyl 6-[(5-cyanopyrazin-2-yl)amino]-4-(2-piperidin-4-ylethylamino)pyridine-3-carboxylate

6-[(5-cyanopyrazin-2-yl)amino]-N-phenyl-4-(piperidin-4-ylmethylamino)pyridine-3-carboxamide

5-[[5-(3-chlorophenyl)-4-[[(2R)-morpholin-2-yl]methylamino]pyridin-2-yl]amino]pyrazine-2-carbonitrile

5-[[5-(3-fluorophenyl)-4-(piperidin-4-ylmethylamino)pyridin-2-yl]amino]pyrazine-2-carbonitrile

5-[[5-(3,5-difluorophenyl)-4-[[(2R)-morpholin-2-yl]methylamino]pyridin-2-yl]amino]pyrazine-2-carbonitrile

1137478-44-4

methyl 6-[(5-cyanopyrazin-2-yl)amino]-4-(piperidin-4-ylmethylamino)pyridine-3-carboxylate

methyl 6-[(5-cyanopyrazin-2-yl)amino]-4-[(1-methylpiperidin-4-yl)methylamino]pyridine-3-carboxylate

1137478-38-6

5-[[5-(2-methylindazol-5-yl)-4-[[(2R)-morpholin-2-yl]methylamino]pyridin-2-yl]amino]pyrazine-2-carbonitrile

methyl 6-[(5-cyanopyrazin-2-yl)amino]-4-(piperidin-3-ylmethylamino)pyridine-3-carboxylate

1168103-91-0

5-[[5-cyano-4-(morpholin-2-ylmethylamino)pyridin-2-yl]amino]pyrazine-2-carbonitrile

methyl 6-[[5-cyano-6-[(3R)-pyrrolidin-3-yl]oxypyrazin-2-yl]amino]-4-methoxypyridine-3-carboxylate

3-[(2S)-1-(dimethylamino)propan-2-yl]oxy-5-[[4-(methylamino)-5-(1-methylpyrazol-4-yl)pyridin-2-yl]amino]pyrazine-2-carbonitrile

methyl 6-[(5-cyanopyrazin-2-yl)amino]-4-[[(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl]methylamino]pyridine-3-carboxylate

5-[[5-(3-methyl-1,2,4-oxadiazol-5-yl)-4-(piperidin-4-ylmethylamino)pyridin-2-yl]amino]pyrazine-2-carbonitrile

5-[[5-(3-hydroxy-3-methylbut-1-ynyl)-4-(piperidin-4-ylmethylamino)pyridin-2-yl]amino]pyrazine-2-carbonitrile

5-[[5-[(E)-4-hydroxybut-1-enyl]-4-(piperidin-4-ylmethylamino)pyridin-2-yl]amino]pyrazine-2-carbonitrile

6-[(5-cyanopyrazin-2-yl)amino]-N-ethyl-4-(piperidin-4-ylmethylamino)pyridine-3-carboxamide

5-[[5-(3-hydroxypropyl)-4-(piperidin-4-ylmethylamino)pyridin-2-yl]amino]pyrazine-2-carbonitrile