Brief Information of the Compound and Protein
Compound Name
2-phenyl-4-piperidin-3-ylsulfanylthieno[3,2-c]pyridine-7-carboxamide
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PubChem ID
CID: 69013596
Canonical SMILES
NC(=O)c1cnc(SC2CCCNC2)c2cc(sc12)-c1ccccc1
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Compound Formula C19H19N3OS2
Compound Structure
Protein Name
Serine/threonine-protein kinase Chk1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CAMK protein kinase group
>
CAMK protein kinase CAMK1 family
>
CAMK protein kinase CHK1 subfamily
Uniprot ID
O14757
Gene Name
CHEK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000007 HT-29 Homo sapiens (Human)  1
1
EC50 = 210 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 56 nM