Brief Information of the Compound and Protein
Compound Name
 Compound Info 
AZD7762
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 PubChem ID
CID: 11152667
SID: 16231456
Canonical SMILES
NC(=O)Nc1cc(sc1C(=O)N[C@H]1CCCNC1)-c1cccc(F)c1
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Compound Formula C17H19FN4O2S
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase Chk1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CAMK protein kinase group
>
CAMK protein kinase CAMK1 family
>
CAMK protein kinase CHK1 subfamily
Uniprot ID
O14757
Gene Name
CHEK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000007 HT-29
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 10 nM
   TI
   LI
   LO
   TS
2
EC50 = 280 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 5 nM
2 IC50 = 6 nM
3 IC50 = 7.89 nM