Brief Information of the Compound and Protein
Compound Name
12-(1-methylpyrazol-3-yl)-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene-4-carbonitrile
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PubChem ID
CID: 58266659
Canonical SMILES
Cn1ccc(n1)-c1cnc2[nH]c3cnc(cc3c2c1)C#N
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Compound Formula C15H10N6
Compound Structure
Protein Name
Serine/threonine-protein kinase Chk1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CAMK protein kinase group
>
CAMK protein kinase CAMK1 family
>
CAMK protein kinase CHK1 subfamily
Uniprot ID
O14757
Gene Name
CHEK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000007 HT-29 Homo sapiens (Human)  1
1
EC50 = 2495 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 33.8 nM