Brief Information of the Compound and Protein
Compound Name
3-(5-Ethyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)-9H-pyrrolo[2,3-b:5,4-c']dipyridine-6-carbonitrile
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PubChem ID
CID: 44546167
SID: 87229047
Canonical SMILES
CCN1CCc2sc(-c3cnc4[nH]c5cnc(C#N)cc5c4c3)cc2C1
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Compound Formula C20H17N5S
Compound Structure
Protein Name
Serine/threonine-protein kinase Chk1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CAMK protein kinase group
>
CAMK protein kinase CAMK1 family
>
CAMK protein kinase CHK1 subfamily
Uniprot ID
O14757
Gene Name
CHEK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000007 HT-29 Homo sapiens (Human)  1
1
EC50 = 50.9 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.78 nM