Brief Information of the Compound and Protein
Compound Name
 Compound Info 
methyl 6-[(5-cyanopyrazin-2-yl)amino]-4-[[(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl]methylamino]pyridine-3-carboxylate
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Canonical SMILES
COC(=O)c1cnc(Nc2cnc(cn2)C#N)cc1NC[C@@H]1C[C@@H]2CC[C@H](C1)N2C
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Compound Formula C21H25N7O2
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase Chk1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CAMK protein kinase group
>
CAMK protein kinase CAMK1 family
>
CAMK protein kinase CHK1 subfamily
Uniprot ID
O14757
Gene Name
CHEK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000007 HT-29
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 2500 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 7 nM