Brief Information of the Compound and Protein
Compound Name
4-[[(3S)-piperidin-3-yl]amino]-2-thiophen-2-ylthieno[3,2-c]pyridine-7-carboxamide
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PubChem ID
CID: 11951724
SID: 17393092
Canonical SMILES
NC(=O)c1cnc(N[C@H]2CCCNC2)c2cc(sc12)-c1cccs1
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Compound Formula C17H18N4OS2
Compound Structure
Protein Name
Serine/threonine-protein kinase Chk1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CAMK protein kinase group
>
CAMK protein kinase CAMK1 family
>
CAMK protein kinase CHK1 subfamily
Uniprot ID
O14757
Gene Name
CHEK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000007 HT-29 Homo sapiens (Human)  1
1
EC50 = 12 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 15 nM