Brief Information of the Compound and Protein
Compound Name
3-(4-(((2R,6S)-2,6-Dimethylpiperidin-1-yl)methyl)phenyl)-9H-pyrrolo[2,3-b:5,4-c']dipyridine-6-carbonitrile
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PubChem ID
CID: 44545828
SID: 87228700
Canonical SMILES
C[C@@H]1CCC[C@H](C)N1Cc1ccc(-c2cnc3[nH]c4cnc(C#N)cc4c3c2)cc1
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Compound Formula C25H25N5
Compound Structure
Protein Name
Serine/threonine-protein kinase Chk1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CAMK protein kinase group
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CAMK protein kinase CAMK1 family
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CAMK protein kinase CHK1 subfamily
Uniprot ID
O14757
Gene Name
CHEK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000007 HT-29 Homo sapiens (Human)  1
1
EC50 = 99.1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.1 nM