Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-(4-(((3R,5S)-3,5-Dimethylpiperidin-1-yl)methyl)phenyl)-9H-pyrrolo[2,3-b:5,4-c']-dipyridine-6-carbonitrile
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 PubChem ID
CID: 58266397
Canonical SMILES
C[C@@H]1C[C@H](C)CN(Cc2ccc(-c3cnc4[nH]c5cnc(C#N)cc5c4c3)cc2)C1
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Compound Formula C25H25N5
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase Chk1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CAMK protein kinase group
>
CAMK protein kinase CAMK1 family
>
CAMK protein kinase CHK1 subfamily
Uniprot ID
O14757
Gene Name
CHEK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000007 HT-29
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 209 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4.2 nM