| Compound ID |
Compound Name |
Compound Formula |
|
CP0566094
|
(E)-3-[4-(1-cyclopropylpyrazol-4-yl)-5-fluoropyridin-3-yl]-N-[4-(morpholin-4-ylmethyl)phenyl]prop-2-enamide
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|
C25H26FN5O2
|
1
|
| 1 |
EC50 = 2.3 nM
|
|
|
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CP0008514
|
(E)-3-[4-(3-methylbenzimidazol-5-yl)pyridin-3-yl]-N-[4-(morpholin-4-ylmethyl)phenyl]prop-2-enamide
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|
C27H27N5O2
|
1
|
| 1 |
EC50 = 2.4 nM
|
|
|
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CP0574099
|
(E)-3-[4-(1-cyclopropylpyrazol-4-yl)pyridin-3-yl]-N-[4-(2-oxa-5-azabicyclo[2.2.1]heptan-5-ylmethyl)phenyl]prop-2-enamide
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|
C26H27N5O2
|
1
|
| 1 |
EC50 = 3.1 nM
|
|
|
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CP0003539
|
(E)-3-[5-fluoro-4-(1-methylpyrazol-4-yl)pyridin-3-yl]-N-[4-(morpholin-4-ylmethyl)phenyl]prop-2-enamide
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|
C23H24FN5O2
|
1
|
| 1 |
EC50 = 3.6 nM
|
|
|
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CP0541453
|
(E)-3-[4-(1-cyclopropylpyrazol-4-yl)pyridin-3-yl]-N-[4-(6-oxa-3-azabicyclo[3.1.1]heptan-3-ylmethyl)phenyl]prop-2-enamide
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|
C26H27N5O2
|
1
|
| 1 |
EC50 = 5.5 nM
|
|
|
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CP0013648
|
(E)-3-[4-(1-methylpyrazol-4-yl)pyridin-3-yl]-N-[2-(2,2,2-trifluoroethyl)-3,4-dihydro-1H-isoquinolin-6-yl]prop-2-enamide
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|
C23H22F3N5O
|
1
|
| 1 |
EC50 = 7 nM
|
|
|
|
CP0003533
|
(E)-3-[4-(1-methylpyrazol-4-yl)pyridin-3-yl]-N-[2-(2,2,2-trifluoroethyl)-3,4-dihydro-1H-isoquinolin-7-yl]prop-2-enamide
Show/Hide
|
C23H22F3N5O
|
1
|
| 1 |
EC50 = 8.4 nM
|
|
|
|
CP0011880
|
(E)-3-[4-(1-cyclopropylpyrazol-4-yl)pyridin-3-yl]-N-[4-[(3,3-difluoroazetidin-1-yl)methyl]phenyl]prop-2-enamide
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|
C24H23F2N5O
|
1
|
| 1 |
EC50 = 8.4 nM
|
|
|
|
CP0003540
|
(E)-3-[4-(3H-benzimidazol-5-yl)pyridin-3-yl]-N-[4-(morpholin-4-ylmethyl)phenyl]prop-2-enamide
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|
C26H25N5O2
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
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CP0014364
|
(E)-3-[4-(1-cyclopropylpyrazol-4-yl)pyridin-3-yl]-N-[4-(morpholin-4-ylmethyl)phenyl]prop-2-enamide
Show/Hide
|
C25H27N5O2
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
|
CP0014610
|
(E)-3-[4-[1-(difluoromethyl)pyrazol-4-yl]pyridin-3-yl]-N-[4-(morpholin-4-ylmethyl)phenyl]prop-2-enamide
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|
C23H23F2N5O2
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
|
CP0010431
|
(E)-3-[4-(2-methoxy-1,3-thiazol-5-yl)pyridin-3-yl]-N-[4-(morpholin-4-ylmethyl)phenyl]prop-2-enamide
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|
C23H24N4O3S
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0014365
|
(E)-3-[4-(1-methylpyrazol-4-yl)pyridin-3-yl]-N-[4-(morpholin-4-ylmethyl)phenyl]prop-2-enamide
Show/Hide
|
C23H25N5O2
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0011877
|
(E)-3-[4-(1-cyclopropylpyrazol-4-yl)pyridin-3-yl]-N-[2-(2,2,2-trifluoroethyl)-3,4-dihydro-1H-isoquinolin-6-yl]prop-2-enamide
Show/Hide
|
C25H24F3N5O
|
1
|
| 1 |
EC50 = 14 nM
|
|
|
|
CP0007445
|
(E)-N-[4-[(2-methylmorpholin-4-yl)methyl]phenyl]-3-[4-(1-methylpyrazol-4-yl)pyridin-3-yl]prop-2-enamide
Show/Hide
|
C24H27N5O2
|
1
|
| 1 |
EC50 = 16 nM
|
|
|
|
CP0003538
|
(E)-N-[4-[(3,3-difluoropyrrolidin-1-yl)methyl]phenyl]-3-[4-(1-methylpyrazol-4-yl)pyridin-3-yl]prop-2-enamide
Show/Hide
|
C23H23F2N5O
|
1
|
| 1 |
EC50 = 17 nM
|
|
|
|
CP0541227
|
(E)-3-[4-(1-methylpyrazol-4-yl)pyridin-3-yl]-N-[4-(3-oxa-8-azabicyclo[3.2.1]octan-8-ylmethyl)phenyl]prop-2-enamide
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|
C25H27N5O2
|
1
|
| 1 |
EC50 = 17 nM
|
|
|
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CP0006942
|
(E)-3-[4-(1-methylpyrazol-4-yl)pyridin-3-yl]-N-[4-(2-oxa-5-azabicyclo[2.2.1]heptan-5-ylmethyl)phenyl]prop-2-enamide
Show/Hide
|
C24H25N5O2
|
1
|
| 1 |
EC50 = 19 nM
|
|
|
|
CP0013102
|
(E)-N-[4-(morpholin-4-ylmethyl)phenyl]-3-[4-(1H-pyrazol-4-yl)pyridin-3-yl]prop-2-enamide
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|
C22H23N5O2
|
1
|
| 1 |
EC50 = 21 nM
|
|
|
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CP0011737
|
(E)-N-[4-[(3-methylmorpholin-4-yl)methyl]phenyl]-3-[4-(1-methylpyrazol-4-yl)pyridin-3-yl]prop-2-enamide
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|
C24H27N5O2
|
1
|
| 1 |
EC50 = 27 nM
|
|
|
|
CP0006943
|
(E)-3-[4-(1-benzylpyrazol-4-yl)pyridin-3-yl]-N-[4-(morpholin-4-ylmethyl)phenyl]prop-2-enamide
Show/Hide
|
C29H29N5O2
|
1
|
| 1 |
EC50 = 28 nM
|
|
|
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CP0010429
|
(E)-N-[4-[(3,3-difluoroazetidin-1-yl)methyl]phenyl]-3-[4-(1-methylpyrazol-4-yl)pyridin-3-yl]prop-2-enamide
Show/Hide
|
C22H21F2N5O
|
1
|
| 1 |
EC50 = 84 nM
|
|
|
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CP0022403
|
3-[4-(1-methylpyrazol-4-yl)pyridin-3-yl]-N-[4-(morpholin-4-ylmethyl)phenyl]propanamide
Show/Hide
|
C23H27N5O2
|
1
|
| 1 |
EC50 = 95 nM
|
|
|
|
CP0010430
|
(E)-3-[4-(5-methoxythiophen-2-yl)pyridin-3-yl]-N-[4-(morpholin-4-ylmethyl)phenyl]prop-2-enamide
Show/Hide
|
C24H25N3O3S
|
1
|
| 1 |
EC50 = 97 nM
|
|
|
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CP0008845
|
(E)-N-[4-(morpholin-4-ylmethyl)phenyl]-3-[4-(1,2-thiazol-4-yl)pyridin-3-yl]prop-2-enamide
Show/Hide
|
C22H22N4O2S
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
|
CP0552690
|
(E)-3-[4-(1-methylpyrazol-4-yl)pyridin-3-yl]-N-phenylprop-2-enamide
Show/Hide
|
C18H16N4O
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
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CP0030646
|
3-[4-(1-cyclopropylpyrazol-4-yl)pyridin-3-yl]-N-[4-(morpholin-4-ylmethyl)phenyl]propanamide
Show/Hide
|
C25H29N5O2
|
1
|
| 1 |
EC50 = 130 nM
|
|
|
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CP0007446
|
(E)-N-[4-(morpholin-4-ylmethyl)phenyl]-3-[4-(1,3-thiazol-5-yl)pyridin-3-yl]prop-2-enamide
Show/Hide
|
C22H22N4O2S
|
1
|
| 1 |
EC50 = 140 nM
|
|
|
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CP0456425
|
(E)-N-[4-(morpholin-4-ylmethyl)phenyl]-3-[4-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyridin-3-yl]prop-2-enamide
Show/Hide
|
C24H24F3N5O2
|
1
|
| 1 |
EC50 = 150 nM
|
|
|
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CP0574602
|
5-[3-[(E)-3-[4-(morpholin-4-ylmethyl)anilino]-3-oxoprop-1-enyl]pyridin-4-yl]thiophene-2-carboxamide
Show/Hide
|
C24H24N4O3S
|
1
|
| 1 |
EC50 = 690 nM
|
|
|
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CP0508361
|
(E)-3-[6-amino-4-(1-methylpyrazol-4-yl)pyridin-3-yl]-N-[4-(morpholin-4-ylmethyl)phenyl]prop-2-enamide
Show/Hide
|
C23H26N6O2
|
1
|
| 1 |
EC50 = 1300 nM
|
|
|
|
CP0432086
|
(E)-3-[4-(1-methylbenzimidazol-5-yl)pyridin-3-yl]-N-[4-(morpholin-4-ylmethyl)phenyl]prop-2-enamide
Show/Hide
|
C27H27N5O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
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CP0543041
|
(E)-3-[4-(1-methylpyrazol-4-yl)-2-oxo-1H-pyridin-3-yl]-N-[4-(morpholin-4-ylmethyl)phenyl]prop-2-enamide
Show/Hide
|
C23H25N5O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
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CP0558968
|
(E)-3-[4-(1-methylpyrazol-4-yl)pyridin-3-yl]prop-2-enamide
Show/Hide
|
C12H12N4O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
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