Brief Information of the Compound and Protein
Compound Name
5-[3-[(E)-3-[4-(morpholin-4-ylmethyl)anilino]-3-oxoprop-1-enyl]pyridin-4-yl]thiophene-2-carboxamide
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PubChem ID
CID: 126568696
Canonical SMILES
NC(=O)c1ccc(s1)-c1ccncc1\C=C\C(=O)Nc1ccc(CN2CCOCC2)cc1
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Compound Formula C24H24N4O3S
Compound Structure
Protein Name
Cyclin-dependent kinase 8
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase CDK family
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CMGC protein kinase CDK8 subfamily
Uniprot ID
P49336
Gene Name
CDK8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000015 SW480 Homo sapiens (Human)  1
1
EC50 = 690 nM
   TI
   LI
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   TS