Brief Information of the Compound and Protein
Compound Name
(E)-3-[4-(1-cyclopropylpyrazol-4-yl)-5-fluoropyridin-3-yl]-N-[4-(morpholin-4-ylmethyl)phenyl]prop-2-enamide
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PubChem ID
CID: 126568548
Canonical SMILES
Fc1cncc(\C=C\C(=O)Nc2ccc(CN3CCOCC3)cc2)c1-c1cnn(c1)C1CC1
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Compound Formula C25H26FN5O2
Compound Structure
Protein Name
Cyclin-dependent kinase 8
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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CMGC protein kinase group
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CMGC protein kinase CDK family
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CMGC protein kinase CDK8 subfamily
Uniprot ID
P49336
Gene Name
CDK8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000015 SW480 Homo sapiens (Human)  1
1
EC50 = 2.3 nM
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