Brief Information of the Compound and Protein
Compound Name
3-[4-(1-cyclopropylpyrazol-4-yl)pyridin-3-yl]-N-[4-(morpholin-4-ylmethyl)phenyl]propanamide
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PubChem ID
CID: 126584623
Canonical SMILES
O=C(CCc1cnccc1-c1cnn(c1)C1CC1)Nc1ccc(CN2CCOCC2)cc1
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Compound Formula C25H29N5O2
Compound Structure
Protein Name
Cyclin-dependent kinase 8
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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CMGC protein kinase group
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CMGC protein kinase CDK family
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CMGC protein kinase CDK8 subfamily
Uniprot ID
P49336
Gene Name
CDK8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000015 SW480 Homo sapiens (Human)  1
1
EC50 = 130 nM
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