Brief Information of the Cell Line and Protein
Cell Line ID: CL000015 , SW480
Synonyms
SW-480
SW 480
SW480E
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0546
Protein ID: PT01425 , Poly [ADP-ribose] polymerase tankyrase-2
Gene Name TNKS2
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID Q9H2K2
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000015  Protein ID: PT01425
 
Compound ID Compound Name Compound Formula
CP0155059
1-[3-[4-(2-chlorophenyl)-5-pyrimidin-4-yl-1,2,4-triazol-3-yl]cyclobutyl]-2-oxo-3H-benzimidazole-5-carbonitrile
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C24H17ClN8O
 1
1
IC50 = 70 nM
   TI
   LI
   LO
   TS
CP0513932
3-[3-[4-(2-chlorophenyl)-5-pyrimidin-4-yl-1,2,4-triazol-3-yl]cyclobutyl]-1H-benzimidazol-2-one
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C23H18ClN7O
 1
1
IC50 = 410 nM
   TI
   LI
   LO
   TS
CP0468769
1-[4-[4-(2-chlorophenyl)-5-pyrimidin-4-yl-1,2,4-triazol-3-yl]cyclohexyl]-2-oxo-3H-benzimidazole-5-carbonitrile
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C26H21ClN8O
 1
1
IC50 = 1490 nM
   TI
   LI
   LO
   TS
CP0273375
3-[4-[4-(2-chlorophenyl)-5-pyrimidin-4-yl-1,2,4-triazol-3-yl]cyclohexyl]-1H-benzimidazol-2-one
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C25H22ClN7O
 1
1
IC50 = 1800 nM
   TI
   LI
   LO
   TS