Brief Information of the Cell Line and Protein
Cell Line ID: CL000015 , SW480
Synonyms
SW-480
SW 480
SW480E
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0546
Protein ID: PT03418 , Protein Tat
Gene Name TAT
Organism Human immunodeficiency virus type 1 group M subtype B (isolate PCV12), HIV-1
Protein Classification Transcription factor
Uniprot ID P04326
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000015  Protein ID: PT03418
 
Compound ID Compound Name Compound Formula
CP0497571
[(1S,2R,6S,8S,11S,12S,15S,16S)-4-carbamoyl-2,16-dimethyl-5-oxo-7-oxapentacyclo[9.7.0.02,8.06,8.012,16]octadecan-15-yl] acetate
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C22H31NO5
 1
1
IC50 = 2600 nM
   TI
   LI
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CP0536023
[(1S,2R,6S,8S,11S,12S,15S,16S)-2,16-dimethyl-4-methylsulfonyl-5-oxo-7-oxapentacyclo[9.7.0.02,8.06,8.012,16]octadecan-15-yl] acetate
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C22H32O6S
 1
1
IC50 = 2600 nM
   TI
   LI
   LO
   TS
CP0409125
methyl (1S,2R,6S,8S,11S,12S,15S,16S)-15-acetyloxy-2,16-dimethyl-5-oxo-7-oxapentacyclo[9.7.0.02,8.06,8.012,16]octadecane-4-carboxylate
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C23H32O6
 1
1
IC50 = 2700 nM
   TI
   LI
   LO
   TS
CP0449074
(1aS,4aS,8aS)-4a-methyl-2-oxo-N-phenyl-3,4,5,6,7,8-hexahydro-1aH-naphtho[1,8a-b]oxirene-3-carboxamide
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C18H21NO3
 1
1
IC50 = 2800 nM
   TI
   LI
   LO
   TS
CP0529592
methyl (1S,2R,6S,8S,11S,12S,15S,16S)-15-hydroxy-2,16-dimethyl-5-oxo-7-oxapentacyclo[9.7.0.02,8.06,8.012,16]octadecane-4-carboxylate
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C21H30O5
 1
1
IC50 = 3600 nM
   TI
   LI
   LO
   TS
CP0212782
7-Chloro-5-(1H-pyrrol-2-yl)-1,3-dihydro-benzo[e][1,4]diazepin-2-one
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C13H10ClN3O
 1
1
IC50 = 4000 nM
   TI
   LI
   LO
   TS
CP0538476
5,5-dimethyl-2-oxo-N-phenyl-7-oxabicyclo[4.1.0]heptane-3-carboxamide
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C15H17NO3
 1
1
IC50 = 4500 nM
   TI
   LI
   LO
   TS
CP0534164
(4R,4aS,8aS)-4-chloro-4a-hydroxy-8a-methyl-3-oxo-N-phenyl-2,4,5,6,7,8-hexahydro-1H-naphthalene-2-carboxamide
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C18H22ClNO3
 1
1
IC50 = 7000 nM
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CP0562333
[(4R,5S,8S,9S,10R,13S,14S,17S)-2-carbamoyl-4-chloro-5-hydroxy-10,13-dimethyl-3-oxo-2,4,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate
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C22H32ClNO5
 1
1
IC50 = 8400 nM
   TI
   LI
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   TS
CP0960799
(4S,5S,10R,13S,17S)-17-Hydroxy-2-methanesulfonyl-10,13-dimethyl-tetradecahydro-20-oxa-cyclopropa[4,5]cyclopenta[a]phenanthren-3-one
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C20H30O5S
 1
1
IC50 = 8400 nM
   TI
   LI
   LO
   TS
CP0494734
(1aS,4aS,8aS)-4a-methyl-2-oxo-3,4,5,6,7,8-hexahydro-1aH-naphtho[1,8a-b]oxirene-3-carboxamide
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C12H17NO3
 1
1
IC50 = 9900 nM
   TI
   LI
   LO
   TS
CP0479910
(1S,2R,6S,8S,11S,12S,15S,16S)-4-(benzenesulfonyl)-15-hydroxy-2,16-dimethyl-7-oxapentacyclo[9.7.0.02,8.06,8.012,16]octadecan-5-one
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C25H32O5S
 1
1
IC50 = 10300 nM
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CP0509418
(1S,2R,6S,8S,11S,12S,15S,16S)-15-hydroxy-2,16-dimethyl-5-oxo-7-oxapentacyclo[9.7.0.02,8.06,8.012,16]octadecane-4-carboxamide
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C20H29NO4
 1
1
IC50 = 14300 nM
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CP0535480
(1S,2R,6S,8S,11S,12S,15S,16S)-15-hydroxy-2,16-dimethyl-7-oxapentacyclo[9.7.0.02,8.06,8.012,16]octadecan-5-one
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C19H28O3
 1
1
IC50 = 15400 nM
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CP0514171
(4R,4aS,8aS)-4-chloro-4a-hydroxy-8a-methyl-3-oxo-2,4,5,6,7,8-hexahydro-1H-naphthalene-2-carboxamide
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C12H18ClNO3
 1
1
IC50 = 16500 nM
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CP0430449
N-(4-methoxyphenyl)-5,5-dimethyl-2-oxo-7-oxabicyclo[4.1.0]heptane-3-carboxamide
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C16H19NO4
 1
1
IC50 = 21400 nM
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CP0439325
[(1S,2R,6S,8S,11S,12S,15S,16S)-4-cyano-2,16-dimethyl-5-oxo-7-oxapentacyclo[9.7.0.02,8.06,8.012,16]octadecan-15-yl] acetate
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C22H29NO4
 1
1
IC50 = 24500 nM
   TI
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CP0492359
(1aS,4aS,8aS)-N-(4-methoxyphenyl)-4a-methyl-2-oxo-3,4,5,6,7,8-hexahydro-1aH-naphtho[1,8a-b]oxirene-3-carboxamide
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C19H23NO4
 1
1
IC50 = 25700 nM
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CP0514178
N-(2,6-dichlorophenyl)-5,5-dimethyl-2-oxo-7-oxabicyclo[4.1.0]heptane-3-carboxamide
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C15H15Cl2NO3
 1
1
IC50 = 31700 nM
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CP0461036
(4S,4aR,8aR)-4-chloro-4a-hydroxy-8a-methyl-3-oxo-2,4,5,6,7,8-hexahydro-1H-naphthalene-2-carboxamide
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C12H18ClNO3
 1
1
IC50 = 32100 nM
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CP0536822
(4R,4aS,8aS)-4-chloro-4a-hydroxy-N-(4-methoxyphenyl)-8a-methyl-3-oxo-2,4,5,6,7,8-hexahydro-1H-naphthalene-2-carboxamide
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C19H24ClNO4
 1
1
IC50 = 33500 nM
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CP0535481
(1aS,4aS,8aS)-4a-methyl-2-oxo-3,4,5,6,7,8-hexahydro-1aH-naphtho[1,8a-b]oxirene-3-carbonitrile
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C12H15NO2
 1
1
IC50 = 34000 nM
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CP0527696
(1aR,4aR,8aR)-4a-methyl-2-oxo-3,4,5,6,7,8-hexahydro-1aH-naphtho[1,8a-b]oxirene-3-carboxamide
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C12H17NO3
 1
1
IC50 = 72000 nM
   TI
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   TS