General Information of the Cell Line
Cell Line ID
CL000276
Cell Line Name
PA-1
Synonyms
PA1
PA I
PAI
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0479
Tissue Information
Ascites
Disease
Ovarian mixed germ cell tumor (NCIt: C8114)
Mixed germ cell tumor (ORDO: Orphanet_180234)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01771, E3 ubiquitin-protein ligase Mdm2
Compound ID Compound Name Compound Formula
CP0778805
(3S,4S)-3-(6-chloro-1H-indol-3-yl)-2-(4-chlorobenzyl)-N-(2-(4-methylpiperazin-1-yl)ethyl)-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxamide
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C32H33Cl2N5O2
 1
1
IC50 = 11500 nM
   TI
   LI
   LO
   TS
CP0676966
1-(4-chlorobenzyl)-5-(4-chlorophenyl)-3-hydroxy-4-phenyl-1H-pyrrol-2(5H)-one
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C23H17Cl2NO2
 1
1
IC50 = 26200 nM
   TI
   LI
   LO
   TS
CP0041876
(4S,5R)-Nutlin-3
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C30H30Cl2N4O4
 1
1
IC50 > 60000 nM
   TI
   LI
   LO
   TS
CP0778804
(3S,4S)-2-(4-chlorobenzyl)-3-(4-chlorophenyl)-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxylic acid
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C23H17Cl2NO3
 1
1
IC50 > 60000 nM
   TI
   LI
   LO
   TS
CP0709749
(3S,4S)-2-(4-chlorobenzyl)-3-(4-chlorophenyl)-N-(2-methoxyethyl)-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxamide
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C26H24Cl2N2O3
 1
1
IC50 = 62500 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Ascites)
Cell Line Name Organism Disease
PEO1 Homo sapiens (Human) BRCA2-associated hereditary breast and ovarian cancer syndrome
MAST Homo sapiens (Human) Breast carcinoma
Ramos Homo sapiens (Human) Burkitt lymphoma
CA46 Homo sapiens (Human) Burkitt lymphoma
CellSensor STAT6-bla RA-1 Homo sapiens (Human) Burkitt lymphoma
NCI-H716 Homo sapiens (Human) Cecum adenocarcinoma
COLO 205 Homo sapiens (Human) Colon adenocarcinoma
COLO 201 Homo sapiens (Human) Colon adenocarcinoma
DiFi Homo sapiens (Human) Colorectal carcinoma
U-2932 Homo sapiens (Human) Diffuse large B-cell lymphoma activated B-cell type
DB Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
HEC-50B Homo sapiens (Human) Endometrial adenocarcinoma
SNU-5 Homo sapiens (Human) Gastric adenocarcinoma
SNU-16 Homo sapiens (Human) Gastric adenocarcinoma
SNU-620 Homo sapiens (Human) Gastric adenocarcinoma
SNU-638 Homo sapiens (Human) Gastric adenocarcinoma
SNU-668 Homo sapiens (Human) Gastric signet ring cell adenocarcinoma
OVCAR-3 Homo sapiens (Human) High grade ovarian serous adenocarcinoma
OVCAR-5 Homo sapiens (Human) High grade ovarian serous adenocarcinoma
COV318 Homo sapiens (Human) High grade ovarian serous adenocarcinoma
ZR-75-1 Homo sapiens (Human) Invasive breast carcinoma of no special type
SK-HEP-1 Homo sapiens (Human) Liver and intrahepatic bile duct epithelial neoplasm
OV-90 Homo sapiens (Human) Ovarian adenocarcinoma
LK2 Homo sapiens (Human) Ovarian carcinoma
RMG-I Homo sapiens (Human) Ovarian clear cell adenocarcinoma
SK-OV-3 Homo sapiens (Human) Ovarian serous cystadenocarcinoma
SKOV3/TR Homo sapiens (Human) Ovarian serous cystadenocarcinoma
AsPC-1 Homo sapiens (Human) Pancreatic ductal adenocarcinoma
HEC Homo sapiens (Human) Peritoneal malignant mesothelioma
Ehrlich-Lettre ascites strain E Mus musculus (Mouse) Malignant neoplasms of the mouse mammary gland
RAW 264.7 Mus musculus (Mouse) Mouse leukemia
L1210 Mus musculus (Mouse) Mouse leukemia
L1210/R81 Mus musculus (Mouse) Mouse leukemia
RAW-Lucia ISG Mus musculus (Mouse) Mouse leukemia
RAW-Lucia ISG-KO-STING Mus musculus (Mouse) Mouse leukemia
RAW 264 Mus musculus (Mouse) Mouse leukemia
J774 Mus musculus (Mouse) Mouse reticulum cell sarcoma
J774A1 Mus musculus (Mouse) Mouse reticulum cell sarcoma
HTC Rattus norvegicus (Rat) Rat hepatocellular carcinoma