Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3S,4S)-3-(6-chloro-1H-indol-3-yl)-2-(4-chlorobenzyl)-N-(2-(4-methylpiperazin-1-yl)ethyl)-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxamide
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 PubChem ID
CID: 24936079
SID: 99346651
Canonical SMILES
CN1CCN(CCNC(=O)[C@H]2c3ccccc3C(=O)N(Cc3ccc(Cl)cc3)[C@@H]2c2c[nH]c3cc(Cl)ccc23)CC1
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Compound Formula C32H33Cl2N5O2
Compound Structure
Protein Name
 Protein Info 
E3 ubiquitin-protein ligase Mdm2
Protein Classification
Other nuclear protein
Uniprot ID
Q00987
Gene Name
MDM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000276 PA-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 11500 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Kd = 5000 nM