Brief Information of the Compound and Protein
Compound Name
1-(4-chlorobenzyl)-5-(4-chlorophenyl)-3-hydroxy-4-phenyl-1H-pyrrol-2(5H)-one
    Show/Hide
PubChem ID
CID: 11848430
SID: 17161229
Canonical SMILES
O=C1C(O)=C(c2ccccc2)C(c2ccc(Cl)cc2)N1Cc1ccc(Cl)cc1
    Show/Hide
Compound Formula C23H17Cl2NO2
Compound Structure
Protein Name
E3 ubiquitin-protein ligase Mdm2
Protein Classification
Other nuclear protein
Uniprot ID
Q00987
Gene Name
MDM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000276 PA-1 Homo sapiens (Human)  1
1
IC50 = 26200 nM
   TI
   LI
   LO
   TS