General Information of the Cell Line
Cell Line ID
CL000163
Cell Line Name
COLO 205
Synonyms
Colo 205
CoLo 205
COLO-205
Colo-205
COLO.205
Colo205
COLO205
Co 205
Colorado 205
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0218
Tissue Information
Ascites
Disease
Colon adenocarcinoma (NCIt: C4349)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01080, ERK activator kinase 1
 Protein Info 
Compound ID Compound Name Compound Formula
CP0158653
 Compound Info 
Pimasertib
   Show/Hide
C15H15FIN3O3
  1
1
IC50 = 1.81 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0116312
 Compound Info 
2-[(2S)-2,3-dihydroxypropyl]-8-(2-fluoro-4-iodoanilino)pyrido[3,4-d]pyridazin-1-one
   Show/Hide
C16H14FIN4O3
  1
1
IC50 = 1.95 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0382258
 Compound Info 
N-[(2S)-2,3-dihydroxypropyl]-5-(2-fluoro-4-iodoanilino)pyrimidine-4-carboxamide
   Show/Hide
C14H14FIN4O3
  1
1
IC50 = 3.41 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0027641
 Compound Info 
(R)-3-(2,3-dihydroxypropyl)-6-fluoro-5-(2-fluoro-4-iodophenylamino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione
   Show/Hide
C17H15F2IN4O4
  1
1
IC50 = 6.92 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0550678
 Compound Info 
2-[(2S)-2,3-dihydroxypropyl]-8-(2-fluoro-4-iodoanilino)-4-methylpyrido[3,4-d]pyridazin-1-one
   Show/Hide
C17H16FIN4O3
  1
1
IC50 = 13.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0273467
 Compound Info 
2-chloro-N-[(2S)-2,3-dihydroxypropyl]-5-(2-fluoro-4-iodoanilino)pyrimidine-4-carboxamide
   Show/Hide
C14H13ClFIN4O3
  1
1
IC50 = 44.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0571209
 Compound Info 
N-(1,3-dihydroxypropan-2-yl)-5-(2-fluoro-4-iodoanilino)pyrimidine-4-carboxamide
   Show/Hide
C14H14FIN4O3
  1
1
IC50 = 55.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0554907
 Compound Info 
N-[(2R)-2,3-dihydroxypropyl]-5-(2-fluoro-4-iodoanilino)pyrimidine-4-carboxamide
   Show/Hide
C14H14FIN4O3
  1
1
IC50 = 56.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0273468
 Compound Info 
5-(2-fluoro-4-iodoanilino)-N-(3-hydroxypropyl)pyrimidine-4-carboxamide
   Show/Hide
C14H14FIN4O2
  1
1
IC50 = 101.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0113690
 Compound Info 
5-(2-fluoro-4-iodoanilino)-N-(2-hydroxyethyl)pyrimidine-4-carboxamide
   Show/Hide
C13H12FIN4O2
  1
1
IC50 = 101.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0317919
 Compound Info 
3-[(2S)-2,3-dihydroxypropyl]-5-(2-fluoro-4-iodoanilino)pyrido[3,4-d]pyrimidin-4-one
   Show/Hide
C16H14FIN4O3
  1
1
IC50 = 108 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0095543
 Compound Info 
3-[(2R)-2,3-dihydroxypropyl]-5-(2-fluoro-4-iodoanilino)pyrido[3,4-d]pyrimidin-4-one
   Show/Hide
C16H14FIN4O3
  1
1
IC50 = 142 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT00991, Histone deacetylase 1
 Protein Info 
Protein ID: PT01466, Telomerase reverse transcriptase
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0000866
 Compound Info 
6-Acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one Hydrochloride
   Show/Hide
 C24H29N7O2  1
1
IC50 = 36 nM
   TI
   LI
   LO
   TS
CP0003433
 Compound Info 
(Arylindolyl)maleimide deriv. 27
   Show/Hide
 C21H16N4O2  1
1
GI50 = 1690 nM
   TI
   LI
   LO
   TS
CP0006321
 Compound Info 
PLX-4032
   Show/Hide
 C23H18ClF2N3O3S  1
1
EC50 = 240 nM
   TI
   LI
   LO
   TS
CP0007711
 Compound Info 
(E)-3-[4-[[2-(2-methyl-1H-indol-3-yl)ethylamino]methyl]phenyl]-N'-propylprop-2-enehydrazide;2,2,2-trifluoroacetic acid
   Show/Hide
 C26H31F3N4O3  1
1
GI50 = 29.8 nM
   TI
   LI
   LO
   TS
CP0010682
 Compound Info 
2-((6-amino-9H-purin-9-yl)methyl)-5-methyl-3-o-tolylquinazolin-4(3H)-one
   Show/Hide
 C22H19N7O  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0011213
 Compound Info 
4,5-dimethoxy-9-oxo-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,17}]octadeca-1(11),2,4,6,12(17),13,15-heptaene-14-carbonitrile
   Show/Hide
 C19H15N3O3  1
1
IC50 = 470 nM
   TI
   LI
   LO
   TS
CP0016389
 Compound Info 
6-(1-ethylpiperidin-4-yl)-N-[5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-yl]-7,8-dihydro-5H-1,6-naphthyridin-2-amine
   Show/Hide
 C30H36F2N8  1
1
IC50 = 57 nM
   TI
   LI
   LO
   TS
CP0016713
 Compound Info 
2-[(E)-2-(2,6-dichlorophenyl)ethenyl]-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]chromen-4-one
   Show/Hide
 C23H21Cl2NO5  1
1
GI50 = 7000 nM
   TI
   LI
   LO
   TS
CP0019438
 Compound Info 
8-[3-(1-benzothiophen-2-yl)-5-chloropyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one
   Show/Hide
 C21H20ClN3OS  1
1
GI50 > 50000 nM
   TI
   LI
   LO
   TS
CP0019439
 Compound Info 
8-[3-(1-benzofuran-2-yl)-5-chloropyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one
   Show/Hide
 C21H20ClN3O2  1
1
GI50 > 50000 nM
   TI
   LI
   LO
   TS
CP0037781
 Compound Info 
3-[3-(azetidin-1-ylmethyl)cyclobutyl]-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine
   Show/Hide
 C29H28N6  1
1
IC50 = 930 nM
   TI
   LI
   LO
   TS
CP0064592
 Compound Info 
[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-15-[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate
   Show/Hide
 C47H51NO14  1
1
GI50 = 7.9 nM
   TI
   LI
   LO
   TS
CP0082019
 Compound Info 
(2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoic acid
   Show/Hide
 C22H21NO2S  1
1
GI50 = 3160 nM
   TI
   LI
   LO
   TS
CP0086475
 Compound Info 
2-[(4-methoxyphenyl)-diphenylmethyl]sulfanylethanamine
   Show/Hide
 C22H23NOS  1
1
GI50 = 210 nM
   TI
   LI
   LO
   TS
CP0091315
 Compound Info 
US9422297, AAG145-136
   Show/Hide
 C17H13ClN4  1
1
GI50 = 638 nM
   TI
   LI
   LO
   TS
CP0104718
 Compound Info 
2,6-difluoro-N-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)-3-(propylsulfonylamino)benzamide
   Show/Hide
 C17H17F2N5O4S  1
1
EC50 = 80 nM
   TI
   LI
   LO
   TS
CP0166079
 Compound Info 
6-hydroxy-N-[[4-(methanesulfonamidomethyl)phenyl]methyl]-N-methyl-3-[(3-methylphenyl)methyl]-2H-indazole-5-carboxamide
   Show/Hide
 C26H28N4O4S  1
1
IC50 = 3700 nM
   TI
   LI
   LO
   TS
CP0238038
 Compound Info 
6-(5-methyl-1H-pyrazol-4-yl)-2-(pyrrolidin-1-ylmethyl)-3H-thieno[3,2-d]pyrimidin-4-one
   Show/Hide
 C15H17N5OS  1
1
EC50 = 1100 nM
   TI
   LI
   LO
   TS
CP0370065
 Compound Info 
5-(4-chlorophenyl)-2-(4-methoxyphenyl)-[1,3]thiazolo[3,2-b][1,2,4]triazole
   Show/Hide
 C17H12ClN3OS  1
1
LC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0383276
 Compound Info 
N-(4-methoxyphenyl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
   Show/Hide
 C16H17N3O2  1
1
GI50 = 20 nM
   TI
   LI
   LO
   TS
CP0521699
 Compound Info 
6-(1H-pyrazol-4-yl)-2-(pyrrolidin-1-ylmethyl)-3H-thieno[3,2-d]pyrimidin-4-one
   Show/Hide
 C14H15N5OS  1
1
EC50 = 7500 nM
   TI
   LI
   LO
   TS
CP0572493
 Compound Info 
N-[4-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8-yl]cyclohexyl]cyclohexanecarboxamide
   Show/Hide
 C33H45N7O3  1
1
IC50 = 280 nM
   TI
   LI
   LO
   TS
CP0897293
 Compound Info 
1-(7-Benzyl-2-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)-6-methoxy-1,2,3,4-tetrahydroquinoline hydrochloride
   Show/Hide
 C24H25ClN4O  1
1
GI50 = 232 nM
   TI
   LI
   LO
   TS
CP0906523
 Compound Info 
7-Benzyl-N-(4-methoxyphenyl)-N,2,5-trimethyl-5H-pyrrolo[3,2-d]pyrimidin-4-amine hydrochloride
   Show/Hide
 C23H25ClN4O  1
1
GI50 = 26.3 nM
   TI
   LI
   LO
   TS
CP0931559
 Compound Info 
2-[(Dimethylamino)methyl]-6-(3-methyl-1H-pyrazol-4-yl)thieno[3,2-d]pyrimidin-4(3H)-one dihydrochloride
   Show/Hide
 C13H17Cl2N5OS  1
1
EC50 = 3200 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Ascites)
Cell Line Name Organism Disease
PEO1
 Cell Line Info 
Homo sapiens (Human) BRCA2-associated hereditary breast and ovarian cancer syndrome
MAST
 Cell Line Info 
Homo sapiens (Human) Breast carcinoma
Ramos
 Cell Line Info 
Homo sapiens (Human) Burkitt lymphoma
CA46
 Cell Line Info 
Homo sapiens (Human) Burkitt lymphoma
CellSensor STAT6-bla RA-1
 Cell Line Info 
Homo sapiens (Human) Burkitt lymphoma
NCI-H716
 Cell Line Info 
Homo sapiens (Human) Cecum adenocarcinoma
COLO 201
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
DiFi
 Cell Line Info 
Homo sapiens (Human) Colorectal carcinoma
U-2932
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma activated B-cell type
DB
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
HEC-50B
 Cell Line Info 
Homo sapiens (Human) Endometrial adenocarcinoma
SNU-5
 Cell Line Info 
Homo sapiens (Human) Gastric adenocarcinoma
SNU-16
 Cell Line Info 
Homo sapiens (Human) Gastric adenocarcinoma
SNU-620
 Cell Line Info 
Homo sapiens (Human) Gastric adenocarcinoma
SNU-638
 Cell Line Info 
Homo sapiens (Human) Gastric adenocarcinoma
SNU-668
 Cell Line Info 
Homo sapiens (Human) Gastric signet ring cell adenocarcinoma
OVCAR-3
 Cell Line Info 
Homo sapiens (Human) High grade ovarian serous adenocarcinoma
OVCAR-5
 Cell Line Info 
Homo sapiens (Human) High grade ovarian serous adenocarcinoma
COV318
 Cell Line Info 
Homo sapiens (Human) High grade ovarian serous adenocarcinoma
ZR-75-1
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
SK-HEP-1
 Cell Line Info 
Homo sapiens (Human) Liver and intrahepatic bile duct epithelial neoplasm
OV-90
 Cell Line Info 
Homo sapiens (Human) Ovarian adenocarcinoma
LK2
 Cell Line Info 
Homo sapiens (Human) Ovarian carcinoma
RMG-I
 Cell Line Info 
Homo sapiens (Human) Ovarian clear cell adenocarcinoma
PA-1
 Cell Line Info 
Homo sapiens (Human) Ovarian mixed germ cell tumor
SK-OV-3
 Cell Line Info 
Homo sapiens (Human) Ovarian serous cystadenocarcinoma
SKOV3/TR
 Cell Line Info 
Homo sapiens (Human) Ovarian serous cystadenocarcinoma
AsPC-1
 Cell Line Info 
Homo sapiens (Human) Pancreatic ductal adenocarcinoma
HEC
 Cell Line Info 
Homo sapiens (Human) Peritoneal malignant mesothelioma
Ehrlich-Lettre ascites strain E
 Cell Line Info 
Mus musculus (Mouse) Malignant neoplasms of the mouse mammary gland
RAW 264.7
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
L1210
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
L1210/R81
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
RAW-Lucia ISG
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
RAW-Lucia ISG-KO-STING
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
RAW 264
 Cell Line Info 
Mus musculus (Mouse) Mouse leukemia
J774
 Cell Line Info 
Mus musculus (Mouse) Mouse reticulum cell sarcoma
J774A1
 Cell Line Info 
Mus musculus (Mouse) Mouse reticulum cell sarcoma
HTC
 Cell Line Info 
Rattus norvegicus (Rat) Rat hepatocellular carcinoma