Brief Information of the Compound and Protein
Compound Name
N-(1,3-dihydroxypropan-2-yl)-5-(2-fluoro-4-iodoanilino)pyrimidine-4-carboxamide
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PubChem ID
CID: 90656531
Canonical SMILES
OCC(CO)NC(=O)c1ncncc1Nc1ccc(I)cc1F
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Compound Formula C14H14FIN4O3
Compound Structure
Protein Name
Dual specificity mitogen-activated protein kinase kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
>
STE protein kinase STE7 family
Uniprot ID
Q02750
Gene Name
MAP2K1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000163 COLO 205 Homo sapiens (Human)  1
1
IC50 = 55.2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 31.3 nM