Brief Information of the Cell Line and Protein
Cell Line ID: CL000163 , COLO 205
Synonyms
Colo 205
CoLo 205
COLO-205
Colo-205
COLO.205
Colo205
COLO205
Co 205
Colorado 205
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0218
Protein ID: PT01466 , Telomerase reverse transcriptase
Gene Name TERT
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID O14746
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000163  Protein ID: PT01466
 
Compound ID Compound Name Compound Formula
CP0781525
1-[[1-[(2S,3R,5R)-2-(hydroxymethyl)-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)tetrahydrofuran-3-yl]triazol-4-yl]methyl]-3-(3-sulfamoylphenyl)urea
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C20H24N8O7S
 1
1
IC50 = 900 nM
   TI
   LI
   LO
   TS
CP0913154
[1-[(2S,3R,5R)-2-(hydroxymethyl)-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)tetrahydrofuran-3-yl]triazol-4-yl]methyl 4-sulfamoylbenzoate
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C20H22N6O8S
 1
1
IC50 = 5900 nM
   TI
   LI
   LO
   TS
CP0964507
4-[[1-[(2S,3R,5R)-2-(hydroxymethyl)-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)tetrahydrofuran-3-yl]triazol-4-yl]methoxy]benzenesulfonamide
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C19H22N6O7S
 1
1
IC50 = 5900 nM
   TI
   LI
   LO
   TS
CP0781526
1-[(2R,4R,5S)-5-(hydroxymethyl)-4-[4-[(2-oxochromen-6-yl)oxymethyl]triazol-1-yl]tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione
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C22H21N5O7
 1
1
IC50 = 14800 nM
   TI
   LI
   LO
   TS
CP0917647
1-[(2R,4R,5S)-4-[4-[(2,2-dioxo-1,2$l^6-benzoxathiin-6-yl)oxymethyl]triazol-1-yl]-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione
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C21H21N5O8S
 1
1
IC50 = 19000 nM
   TI
   LI
   LO
   TS