Brief Information of the Cell Line and Protein
Cell Line ID: CL000163 , COLO 205
Synonyms
Colo 205
CoLo 205
COLO-205
Colo-205
COLO.205
Colo205
COLO205
Co 205
Colorado 205
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0218
Protein ID: PT00991 , Histone deacetylase 1
Gene Name HDAC1
Organism Homo sapiens, Human
Protein Classification Epigenetic regulator
Uniprot ID Q13547
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000163  Protein ID: PT00991
 
Compound ID Compound Name Compound Formula
CP0106933
6-[3-(4-Iodo-benzoyl)-ureido]-hexanoic acid hydroxyamide
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C14H18IN3O4
 1
1
IC50 = 870 nM
   TI
   LI
   LO
   TS
CP0106940
6-[3-(4-Bromo-benzoyl)-ureido]-hexanoic acid hydroxyamide
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C14H18BrN3O4
 1
1
IC50 = 870 nM
   TI
   LI
   LO
   TS
CP0305712
6-[3-(3-amino-4-chloro-benzoyl)-ureido]-hexanoic acid hydroxyamide
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C14H19ClN4O4
 1
1
IC50 = 1250 nM
   TI
   LI
   LO
   TS
CP0315034
6-[3-(4-Chloro-benzoyl)-ureido]-hexanoic acid hydroxyamide
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C14H18ClN3O4
 1
1
IC50 = 1600 nM
   TI
   LI
   LO
   TS
CP0324871
6-{3-[4-(2-Diethylamino-ethylamino)-3-nitro-benzoyl]-ureido}-hexanoic acid hydroxyamide
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C20H32N6O6
 1
1
IC50 = 1700 nM
   TI
   LI
   LO
   TS
CP0038698
6-[3-(Naphthalene-2-carbonyl)-ureido]-hexanoic acid hydroxyamide
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C18H21N3O4
 1
1
IC50 = 2150 nM
   TI
   LI
   LO
   TS
CP0003832
N'-hydroxy-N-phenyloctanediamide
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C14H20N2O3
 1
1
IC50 = 2200 nM
   TI
   LI
   LO
   TS
CP0038629
6-(3-Benzoyl-ureido)-hexanoic acid hydroxyamide
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C14H19N3O4
 1
1
IC50 = 2210 nM
   TI
   LI
   LO
   TS
CP0265350
6-[3-(4-Nitro-benzoyl)-ureido]-hexanoic acid hydroxyamide
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C14H18N4O6
 1
1
IC50 = 2310 nM
   TI
   LI
   LO
   TS
CP0324870
6-[3-(4-tert-Butyl-benzoyl)-ureido]-hexanoic acid hydroxyamide
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C18H27N3O4
 1
1
IC50 = 2350 nM
   TI
   LI
   LO
   TS
CP0305713
6-{3-[3-nitro-4-(2-pyrrolidin-1-yl-ethylamino)-benzoyl]-ureido}-hexanoic acidhydroxyamide
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C20H30N6O6
 1
1
IC50 = 2420 nM
   TI
   LI
   LO
   TS
CP0305711
6-[3-(4-Fluoro-benzoyl)-ureido]-hexanoic acid hydroxyamide
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C14H18FN3O4
 1
1
IC50 = 2550 nM
   TI
   LI
   LO
   TS
CP0038694
7-(3-Benzoyl-ureido)-heptanoic acid hydroxyamide
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C15H21N3O4
 1
1
IC50 = 2680 nM
   TI
   LI
   LO
   TS
CP0315037
6-[3-(3-Nitro-benzoyl)-ureido]-hexanoic acid hydroxyamide
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C14H18N4O6
 1
1
IC50 = 2800 nM
   TI
   LI
   LO
   TS
CP0038703
6-{3-[2-Butyl-1-(2-pyrrolidin-1-yl-ethyl)-1H-benzimidazole-5-carbonyl]-ureido}-hexanoic acidhydroxyamide
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C25H38N6O4
 1
1
IC50 = 2910 nM
   TI
   LI
   LO
   TS
CP0038696
6-[3-(2,6-Dichloro-benzoyl)-ureido]-hexanoic acid hydroxyamide
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C14H17Cl2N3O4
 1
1
IC50 = 2950 nM
   TI
   LI
   LO
   TS
CP0315035
6-[3-(3-Bromo-benzoyl)-ureido]-hexanoic acid hydroxyamide
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C14H18BrN3O4
 1
1
IC50 = 3150 nM
   TI
   LI
   LO
   TS
CP0038695
6-(3-benzoyl-1-benzyl-ureido)-hexanoic acid hydroxyamide
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C21H25N3O4
 1
1
IC50 = 3190 nM
   TI
   LI
   LO
   TS
CP0038701
6-[3-(3-Nitro-4-piperidin-1-yl-benzoyl)-ureido]-hexanoic acid hydroxyamide
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C19H27N5O6
 1
1
IC50 = 3250 nM
   TI
   LI
   LO
   TS
CP0363947
6-[3-(3-Nitro-4-pyrrolidin-1-yl-benzoyl)-ureido]-hexanoic acid hydroxyamide
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C18H25N5O6
 1
1
IC50 = 3450 nM
   TI
   LI
   LO
   TS
CP0305714
6-{3-[1-(3-Dimethylamino-2,2-dimethyl-propyl)-1H-benzoimidazole-5-carbonyl]-ureido}-hexanoicacid hydroxyamide
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C22H34N6O4
 1
1
IC50 = 3700 nM
   TI
   LI
   LO
   TS
CP0262040
6-{3-[1-(3-Phenyl-propyl)-1H-benzimidazole-5-carbonyl]-ureido}-hexanoic acid hydroxyamide
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C24H29N5O4
 1
1
IC50 = 3750 nM
   TI
   LI
   LO
   TS
CP0038702
6-{3-[1-(2-Diethylamino-ethyl)-1H-benzimidazole-5-carbonyl]-ureido}-hexanoic acid hydroxyamide
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C21H32N6O4
 1
1
IC50 = 5100 nM
   TI
   LI
   LO
   TS
CP0265351
6-{3-[2-phenethyl-1-(2-pyrrolidin-1-yl-ethyl)-1H-benzimidazole-5-carbonyl]-ureido}-hexanoic acid hydroxyamide
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C29H38N6O4
 1
1
IC50 = 5380 nM
   TI
   LI
   LO
   TS
CP0315040
8-(3-Benzoyl-ureido)-octanoic acid hydroxyamide
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C16H23N3O4
 1
1
IC50 = 8280 nM
   TI
   LI
   LO
   TS
CP0093532
7-(3-Benzoyl-1-pyridin-2-ylmethyl-ureido)-heptanoic acid hydroxyamide
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C21H26N4O4
 1
1
IC50 = 9060 nM
   TI
   LI
   LO
   TS
CP0315038
6-[3-(1-Phenethyl-1H-benzimidazole-5-carbonyl)-ureido]-hexanoic acid hydroxyamide
   Show/Hide
C23H27N5O4
 1
1
IC50 = 9700 nM
   TI
   LI
   LO
   TS
CP0106934
6-[3-(4-pyrimidin-5-yl-benzoyl)-ureido]-hexanoic acid hydroxyamide
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C18H21N5O4
 1
1
IC50 = 10000 nM
   TI
   LI
   LO
   TS
CP0363948
6-{3-[4-(4-Methyl-piperazin-1-yl)-3-nitro-benzoyl]-ureido}-hexanoic acid hydroxyamide
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C19H28N6O6
 1
1
IC50 = 11500 nM
   TI
   LI
   LO
   TS
CP0106935
6-[3-(4-Morpholin-4-yl-3-nitro-benzoyl)-ureido]-hexanoic acid hydroxyamide
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C18H25N5O7
 1
1
IC50 = 12000 nM
   TI
   LI
   LO
   TS
CP0038700
6-[3-(4-phenylacetylamino-benzoyl)-ureido]-hexanoic acid hydroxyamide
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C22H26N4O5
 1
1
IC50 = 13200 nM
   TI
   LI
   LO
   TS
CP0360093
6-(3-Benzoyl-1-pyridin-2-ylmethyl-ureido)-hexanoic acid hydroxyamide
   Show/Hide
C20H24N4O4
 1
1
IC50 = 14700 nM
   TI
   LI
   LO
   TS
CP0269262
6-{3-[1-(2-Dimethylamino-ethyl)-1H-benzimidazole-5-carbonyl]-ureido}-hexanoic acidhydroxyamide
   Show/Hide
C19H28N6O4
 1
1
IC50 = 19500 nM
   TI
   LI
   LO
   TS
CP0262039
6-[3-(4-benzenesulfonylamino-benzoyl)-ureido]-hexanoic acid hydroxyamide
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C20H24N4O6S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS