Brief Information of the Compound and Protein
Compound Name
2-chloro-N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-7-(4-ethylpiperazin-1-yl)quinazolin-4-amine
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PubChem ID
CID: 127046448
Canonical SMILES
CCN1CCN(CC1)c1ccc2c(Nc3cc(CCc4cc(OC)cc(OC)c4)[nH]n3)nc(Cl)nc2c1
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Compound Formula C27H32ClN7O2
Compound Structure
Protein Name
Fibroblast growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P21802
Gene Name
FGFR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000431 SNU-16 Homo sapiens (Human)  1
1
IC50 = 108.2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.6 nM