Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2,4-difluoro-6-[5-[[(1R)-2-hydroxy-1-phenylethyl]amino]-3-(3-methyl-2H-indazol-5-yl)pyridin-2-yl]phenol
    Show/Hide
 PubChem ID
CID: 137650511
Canonical SMILES
Cc1n[nH]c2ccc(cc12)-c1cc(N[C@@H](CO)c2ccccc2)cnc1-c1cc(F)cc(F)c1O
    Show/Hide
Compound Formula C27H22F2N4O2
Compound Structure
Protein Name
 Protein Info 
Fibroblast growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P21802
Gene Name
FGFR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000431 SNU-16
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 280.1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3.4 nM