Brief Information of the Compound and Protein
Compound Name
4-chloro-2-[5-[[(1R)-2-hydroxy-1-phenylethyl]amino]-3-isoquinolin-6-ylpyridin-2-yl]phenol
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PubChem ID
CID: 137631967
Canonical SMILES
OC[C@H](Nc1cnc(-c2cc(Cl)ccc2O)c(c1)-c1ccc2cnccc2c1)c1ccccc1
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Compound Formula C28H22ClN3O2
Compound Structure
Protein Name
Fibroblast growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P21802
Gene Name
FGFR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000431 SNU-16 Homo sapiens (Human)  1
1
IC50 = 249 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2 nM