General Information of the Compound
| Compound ID |
CP0016093
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| Compound Name |
(5-(1-benzyl-1H-indazol-3-yl)furan-2-yl)methanol
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| Synonyms |
(5-(1-benzyl-1H-indazol-3-yl)furan-2-yl)methanol
1-Benzyl-3-(5-hydroxymethyl-2-furyl)indazole
154453-18-6
170632-47-0
3-(5'-Hydroxymethyl-2'-furyl)-1-benzyl indazole
3-(5'-Hydroxymethyl-2'-furyl)-1-benzylindazole
5-[1-(Phenylmethyl)-1H-indazol-3-yl]-2-furanmethanol
515CC1WPTE
C19H16N2O2
CHEMBL333985
Lificiguat
Lificiguat(YC-1)
OQQVFCKUDYMWGV-UHFFFAOYSA-N
PMID26882240-Compound-1
UNII-515CC1WPTE
YC 1
YC-1
[5-(1-benzyl-1H-indazol-3-yl)furan-2-yl]methanol
[5-(1-benzyl-1h-indazol-3-yl)-2-furyl]methanol
yc-1
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| Structure |
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| Formula |
C19H16N2O2
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| Molecular Weight |
304.349
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| Canonical SMILES |
OCc1ccc(o1)-c1nn(Cc2ccccc2)c2ccccc12
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| InChI |
InChI=1S/C19H16N2O2/c22-13-15-10-11-18(23-15)19-16-8-4-5-9-17(16)21(20-19)12-14-6-2-1-3-7-14/h1-11,22H,12-13H2
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| InChIKey |
OQQVFCKUDYMWGV-UHFFFAOYSA-N
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| CAS |
154453-18-6
170632-47-0
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02791, Hypoxia-inducible factor 1-alpha
Cell-based Assay
Cell Viability or Cytotoxicity Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000067 | HCT 116 | Homo sapiens (Human) | 1 |
| 1 |
IC50 = 2200 nM
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Clinical Information about the Compound
Drug 1 ( (5-(1-benzyl-1H-indazol-3-yl)furan-2-yl)methanol )
| Drug Name | (5-(1-benzyl-1H-indazol-3-yl)furan-2-yl)methanol | ||
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| Target(s) | |||