Brief Information of the Compound and Protein
Compound Name
2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isonicotinic acid methyl ester
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PubChem ID
CID: 24811989
SID: 49758923
Canonical SMILES
COC(=O)c1ccnc(NC(=O)COc2ccc(cc2)C23CC4CC(CC(C4)C2)C3)c1
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Compound Formula C25H28N2O4
Compound Structure
Protein Name
Hypoxia-inducible factor 1-alpha
Protein Classification
Transcription factor
Uniprot ID
Q16665
Gene Name
HIF1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000275 AGS Homo sapiens (Human)  1
1
IC50 = 2000 nM
   TI
   LI
   LO
   TS
CL000273 Hep 3B2.1-7 Homo sapiens (Human)  1
1
IC50 = 1200 nM
   TI
   LI
   LO
   TS
CL000274 SK-HEP-1 Homo sapiens (Human)  1
1
IC50 = 1030 nM
   TI
   LI
   LO
   TS