Brief Information of the Cell Line and Protein
Cell Line ID: CL000084 , SK-OV-3
 Cell Line Info 
Synonyms
SKOV-3
SK-OV3
SK.OV.3
SKOV3
Skov3
SKO3
SKOV3 (S)
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0532
Protein ID: PT01058 , Disintegrin and metalloproteinase domain-containing protein 17
 Protein Info 
Gene Name ADAM17
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P78536
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000084
 Cell Line Info 
 Protein ID: PT01058
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0062139
 Compound Info 
(R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(hydroxyamino)-4-oxobutylcarbamate
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C22H25N3O7S
  2
1
IC50 = 14 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 966 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0132610
 Compound Info 
(2R)-5-(carbamoylamino)-2-[[4-[(3,5-dibromophenyl)methoxy]phenyl]sulfonylamino]-N-hydroxypentanamide
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C19H22Br2N4O6S
  2
1
IC50 = 58 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 4272 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0073959
 Compound Info 
benzyl N-[(4R)-4-[[4-[(3,5-dibromophenyl)methoxy]phenyl]sulfonylamino]-5-(hydroxyamino)-5-oxopentyl]carbamate
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C26H27Br2N3O7S
  2
1
IC50 = 350 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 5641 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0109071
 Compound Info 
benzyl N-[(3R)-3-[[4-[(3,5-dibromophenyl)methoxy]phenyl]sulfonylamino]-4-(hydroxyamino)-4-oxobutyl]carbamate
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C25H25Br2N3O7S
  2
1
IC50 = 2096 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 9519 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0132603
 Compound Info 
2-[[4-[(3,5-dibromophenyl)methoxy]phenyl]sulfonylamino]-N-hydroxyacetamide
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C15H14Br2N2O5S
  2
1
IC50 = 5301 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS