| Compound ID |
Compound Name |
Compound Formula |
|
CP0515066
|
(2S)-N-(4-chlorophenyl)-2-[6-(trifluoromethyl)spiro[2H-1-benzofuran-3,4'-cyclohexane]-1'-yl]propanamide
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|
C23H23ClF3NO2
|
1
|
| 1 |
IC50 = 3.9 nM
|
|
|
|
CP0165127
|
CHEMBL4161733
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|
C24H24ClFN2O
|
1
|
| 1 |
IC50 = 4.2 nM
|
|
|
|
CP0553240
|
N-(4-chlorophenyl)-3-cyclopropyl-2-[6-(trifluoromethyl)spiro[2H-1-benzofuran-3,4'-piperidine]-1'-yl]propanamide
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|
C25H26ClF3N2O2
|
1
|
| 1 |
IC50 = 4.4 nM
|
|
|
|
CP0564727
|
N-(4-chloro-2-fluorophenyl)-2-[4-(6-fluoroquinolin-4-yl)-2,3,6,7-tetrahydroazepin-1-yl]-2-oxoacetamide
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|
C23H18ClF2N3O2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0421979
|
(2S)-N-(4-chlorophenyl)-2-[6-(trifluoromethyl)spiro[2H-1-benzofuran-3,4'-cyclohexane]-1'-yl]propanamide
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|
C23H23ClF3NO2
|
1
|
| 1 |
IC50 = 5.1 nM
|
|
|
|
CP0485014
|
(2S)-N-(4-chlorophenyl)-2-[6-(trifluoromethyl)spiro[2H-furo[2,3-b]pyridine-3,4'-cyclohexane]-1'-yl]propanamide
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|
C22H22ClF3N2O2
|
1
|
| 1 |
IC50 = 5.4 nM
|
|
|
|
CP0267264
|
N-(4-chlorophenyl)-2-[(3R,4R)-4-(6-fluoroquinolin-4-yl)-3-hydroxypiperidin-1-yl]-2-oxoacetamide
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|
C22H19ClFN3O3
|
1
|
| 1 |
IC50 = 6.1 nM
|
|
|
|
CP0497252
|
(2R)-N-(4-chlorophenyl)-2-[6-(trifluoromethyl)spiro[2H-1-benzofuran-3,4'-cyclohexane]-1'-yl]propanamide
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|
C23H23ClF3NO2
|
1
|
| 1 |
IC50 = 6.6 nM
|
|
|
|
CP0512750
|
(2S)-N-(5-chloropyridin-2-yl)-2-[6-(trifluoromethyl)spiro[2H-1-benzofuran-3,4'-cyclohexane]-1'-yl]butanamide
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|
C23H24ClF3N2O2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0532965
|
N-(4-chloro-2-fluorophenyl)-2-[4-(6-fluoroquinolin-4-yl)piperidin-1-yl]-2-oxoacetamide
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|
C22H18ClF2N3O2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0479986
|
(2S)-N-(4-chlorophenyl)-2-[5-(trifluoromethyl)spiro[2H-furo[2,3-b]pyridine-3,4'-cyclohexane]-1'-yl]propanamide
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|
C22H22ClF3N2O2
|
1
|
| 1 |
IC50 = 7.9 nM
|
|
|
|
CP0564726
|
N-(4-chloro-2-fluorophenyl)-2-[4-(6-fluoroquinolin-4-yl)azepan-1-yl]-2-oxoacetamide
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|
C23H20ClF2N3O2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0424946
|
N-(4-chlorophenyl)-2-[2-methyl-6-(trifluoromethyl)spiro[1H-isoindole-3,4'-cyclohexane]-1'-yl]propanamide
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|
C24H26ClF3N2O
|
1
|
| 1 |
IC50 = 8.3 nM
|
|
|
|
CP0357716
|
N-(4-chlorophenyl)-2-[3,3-difluoro-4-(6-fluoroquinolin-4-yl)piperidin-1-yl]-2-oxoacetamide
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|
C22H17ClF3N3O2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0488942
|
N-(4-chlorophenyl)-2-methyl-2-[6-(trifluoromethyl)spiro[2H-1-benzofuran-3,4'-piperidine]-1'-yl]propanamide
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|
C23H24ClF3N2O2
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0352753
|
(2S)-N-(4-chlorophenyl)-2-[6-(trifluoromethyl)spiro[2H-1-benzofuran-3,4'-piperidine]-1'-yl]butanamide
Show/Hide
|
C23H24ClF3N2O2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0479984
|
N-(4-chlorophenyl)-2-[7-(trifluoromethyl)spiro[2,3-dihydrochromene-4,4'-piperidine]-1'-yl]butanamide
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|
C24H26ClF3N2O2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0236732
|
4-amino-N-(3-chloro-4-fluorophenyl)-N′-hydroxy-1,2,5-oxadiazole-3-carboximidamide
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|
C9H7ClFN5O2
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0267265
|
N-(4-chlorophenyl)-2-[4-(6-fluoroquinolin-4-yl)piperidin-1-yl]-2-oxoacetamide
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|
C22H19ClFN3O2
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0492096
|
N-(4-chlorophenyl)-2-[4-(6-chloroquinolin-4-yl)piperidin-1-yl]-2-oxoacetamide
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|
C22H19Cl2N3O2
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0558720
|
N-(4-chlorophenyl)-2-[4-(7-fluoroquinolin-4-yl)piperidin-1-yl]-2-oxoacetamide
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|
C22H19ClFN3O2
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0540126
|
N-[4-(difluoromethyl)phenyl]-2-[4-(6-fluoroquinolin-4-yl)piperidin-1-yl]-2-oxoacetamide
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|
C23H20F3N3O2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0559923
|
N-(4-chlorophenyl)-2-[6-(trifluoromethyl)spiro[2H-1-benzofuran-3,4'-piperidine]-1'-yl]propanamide
Show/Hide
|
C22H22ClF3N2O2
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0267266
|
N-(4-chlorophenyl)-2-[4-(6-fluoroquinolin-4-yl)-3,3-dimethylpiperidin-1-yl]-2-oxoacetamide
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|
C24H23ClFN3O2
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0540123
|
N-(4-chlorophenyl)-2-[6-(difluoromethyl)spiro[2H-1-benzofuran-3,4'-piperidine]-1'-yl]-2-oxoacetamide
Show/Hide
|
C21H19ClF2N2O3
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0512933
|
N-(4-chlorophenyl)-2-oxo-2-[6-(trifluoromethyl)spiro[2H-1-benzofuran-3,4'-piperidine]-1'-yl]acetamide
Show/Hide
|
C21H18ClF3N2O3
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0315168
|
N-(4-cyanophenyl)-2-[4-(6-fluoroquinolin-4-yl)piperidin-1-yl]-2-oxoacetamide
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|
C23H19FN4O2
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0479985
|
N-(4-chlorophenyl)-2-spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylpropanamide
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|
C22H25ClN2O
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0535044
|
N-(4-chlorophenyl)-2-[(3S,4S)-4-(6-fluoroquinolin-4-yl)-3-hydroxypiperidin-1-yl]-2-oxoacetamide
Show/Hide
|
C22H19ClFN3O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0558798
|
(2R)-N-(4-chlorophenyl)-2-[6-(trifluoromethyl)spiro[2H-1-benzofuran-3,4'-cyclohexane]-1'-yl]propanamide
Show/Hide
|
C23H23ClF3NO2
|
1
|
| 1 |
IC50 = 69 nM
|
|
|
|
CP0512935
|
N-(5-chloropyridin-2-yl)-2-[4-(6-fluoroquinolin-4-yl)piperidin-1-yl]-2-oxoacetamide
Show/Hide
|
C21H18ClFN4O2
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0540127
|
N-(5-chloropyridin-2-yl)-2-oxo-2-[6-(trifluoromethyl)spiro[2H-1-benzofuran-3,4'-piperidine]-1'-yl]acetamide
Show/Hide
|
C20H17ClF3N3O3
|
1
|
| 1 |
IC50 = 73 nM
|
|
|
|
CP0534579
|
N-(4-chlorophenyl)-4-hydroxy-2-[6-(trifluoromethyl)spiro[2H-1-benzofuran-3,4'-piperidine]-1'-yl]butanamide
Show/Hide
|
C23H24ClF3N2O3
|
1
|
| 1 |
IC50 = 86 nM
|
|
|
|
CP0353856
|
N-(4-chlorophenyl)-2-oxo-2-(4-phenylpiperidin-1-yl)acetamide
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|
C19H19ClN2O2
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0535043
|
2-[4-(6-fluoroquinolin-4-yl)piperidin-1-yl]-2-oxo-N-[4-(trifluoromethyl)phenyl]acetamide
Show/Hide
|
C23H19F4N3O2
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0511868
|
(2R)-N-(4-chlorophenyl)-2-[6-(trifluoromethyl)spiro[2H-1-benzofuran-3,4'-piperidine]-1'-yl]butanamide
Show/Hide
|
C23H24ClF3N2O2
|
1
|
| 1 |
IC50 = 109 nM
|
|
|
|
CP0513594
|
N-(4-chlorophenyl)-2-[(3S,4R)-4-(6-fluoroquinolin-4-yl)-3-hydroxypiperidin-1-yl]-2-oxoacetamide
Show/Hide
|
C22H19ClFN3O3
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0540125
|
N-(4-chlorophenyl)-2-[4-(6-cyanoquinolin-4-yl)piperidin-1-yl]-2-oxoacetamide
Show/Hide
|
C23H19ClN4O2
|
1
|
| 1 |
IC50 = 118 nM
|
|
|
|
CP0532964
|
N-(5-chloropyridin-2-yl)-2-[4-(2,3-dichlorophenyl)piperidin-1-yl]-2-oxoacetamide
Show/Hide
|
C18H16Cl3N3O2
|
1
|
| 1 |
IC50 = 245 nM
|
|
|
|
CP0534581
|
N-(4-chlorophenyl)-2-[6-(trifluoromethyl)spiro[2H-1-benzofuran-3,4'-piperidine]-1'-yl]acetamide
Show/Hide
|
C21H20ClF3N2O2
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0564723
|
N-(5-chloropyridin-2-yl)-2-[4-[3-chloro-2-(trifluoromethyl)pyridin-4-yl]piperidin-1-yl]-2-oxoacetamide
Show/Hide
|
C18H15Cl2F3N4O2
|
1
|
| 1 |
IC50 = 301 nM
|
|
|
|
CP0492095
|
2-(3-bromo-4-fluorophenyl)imino-2-(hydroxyamino)-N-[3-(methanesulfonamido)propyl]acetamide
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|
C12H16BrFN4O4S
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0540124
|
N-(5-chloropyridin-2-yl)-2-oxo-2-(4-pyrazolo[1,5-a]pyrimidin-7-ylpiperidin-1-yl)acetamide
Show/Hide
|
C18H17ClN6O2
|
1
|
| 1 |
IC50 = 433 nM
|
|
|
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CP0558725
|
N-(5-chloropyridin-2-yl)-2-oxo-2-spiro[2H-1-benzofuran-3,4'-piperidine]-1'-ylacetamide
Show/Hide
|
C19H18ClN3O3
|
1
|
| 1 |
IC50 = 490 nM
|
|
|
|
CP0557043
|
N-(4-chlorophenyl)-2-spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylacetamide
Show/Hide
|
C21H23ClN2O
|
1
|
| 1 |
IC50 = 670 nM
|
|
|
|
CP0512932
|
N-(4-chlorophenyl)-2-oxo-2-[6-(trifluoromethyl)spiro[2H-1-benzofuran-3,4'-azepane]-1'-yl]acetamide
Show/Hide
|
C22H20ClF3N2O3
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
|
CP0535042
|
2-(3-chloro-4-fluorophenyl)imino-2-(hydroxyamino)-N-[3-(sulfamoylamino)propyl]acetamide
Show/Hide
|
C11H15ClFN5O4S
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
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CP0553681
|
N-(3-chloro-4-fluorophenyl)-2-oxo-2-(4-phenylpiperidin-1-yl)acetamide
Show/Hide
|
C19H18ClFN2O2
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
|
CP0512934
|
N-(4-chlorophenyl)-2-[(3R,4S)-4-(6-fluoroquinolin-4-yl)-3-hydroxypiperidin-1-yl]-2-oxoacetamide
Show/Hide
|
C22H19ClFN3O3
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
|
CP0367369
|
N'-(3-chloro-4-fluorophenyl)-N-hydroxy-2-oxo-2-(4-phenylpiperidin-1-yl)ethanimidamide
Show/Hide
|
C19H19ClFN3O2
|
1
|
| 1 |
IC50 = 14000 nM
|
|
|
|
CP0357715
|
2-(3-chloro-4-fluorophenyl)imino-2-(hydroxyamino)acetamide
Show/Hide
|
C8H7ClFN3O2
|
1
|
| 1 |
IC50 = 24000 nM
|
|
|
