Brief Information of the Compound and Protein
Compound Name
(2S,3S)-Ethyl 3-(4-(3-Bromoanilino)quinazolin-6-ylcarbamoyl)oxirane-2-carboxylate
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PubChem ID
CID: 70681325
Canonical SMILES
O=C(O)[C@H]1O[C@@H]1C(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1
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Compound Formula C18H13BrN4O4
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431 Homo sapiens (Human)  2
1
IC50 = 34 nM
   TI
   LI
   LO
   TS
2
IC50 = 68 nM
   TI
   LI
   LO
   TS