Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-3-methyl-N-(2-morpholinoethyl)-1H-pyrrolo[3,2-d]pyridazine-2-carboxamide
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 PubChem ID
CID: 46879471
Canonical SMILES
Cc1c([nH]c2cnnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12)C(=O)NCCN1CCOCC1
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Compound Formula C26H28ClN7O3
Compound Structure
Protein Name
 Protein Info 
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 867 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 > 10000 nM