Brief Information of the Compound and Protein
Compound Name
4-N-[3-(trifluoromethyl)phenyl]quinazoline-4,6-diamine
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PubChem ID
CID: 5328188
SID: 85847584
Canonical SMILES
Nc1ccc2ncnc(Nc3cccc(c3)C(F)(F)F)c2c1
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Compound Formula C15H11F3N4
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431 Homo sapiens (Human)  1
1
IC50 = 574 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 575.44 nM