Brief Information of the Compound and Protein
Compound Name
N-[4-(3-chloro-4-fluoroanilino)-7-(2-methoxyethoxy)pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide
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PubChem ID
CID: 10549915
SID: 15576970
Canonical SMILES
COCCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2nc1NC(=O)C=C
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Compound Formula C19H17ClFN5O3
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431 Homo sapiens (Human)  1
1
IC50 = 377 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.97 nM