Brief Information of the Compound and Protein
Compound Name
4-[(3-Bromophenyl)amino]-6-chloropyrido[3,2-d]pyrimidine
    Show/Hide
PubChem ID
CID: 5328275
SID: 15546662
Canonical SMILES
Clc1ccc2ncnc(Nc3cccc(Br)c3)c2n1
    Show/Hide
Compound Formula C13H8BrClN4
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431 Homo sapiens (Human)  1
1
IC50 = 18 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 18.2 nM